research Leydig Cell Hyperplasia and Adenomas in Mice Treated with Finasteride, a 5α-Reductase Inhibitor: A Possible Mechanism
High doses of finasteride cause cell growth and tumors in mice.
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research Alopecia areata presenting in 2 kidney-pancreas transplant recipients taking cyclosporine
Two transplant patients on cyclosporine unexpectedly developed hair loss.
research Phase II study of safusidenib erbumine in patients with chemotherapy- and radiotherapy-naïve isocitrate dehydrogenase 1-mutated WHO grade 2 gliomas
Safusidenib erbumine shows promise as a treatment for certain brain tumors, but mild side effects like hair loss need attention.
research Anti-inflammatory activity of ointments of indomethacin and its calcium salt applied to abdominal skin of rat.
IND-Ca ointment effectively reduces inflammation with minimal skin irritation.
research Hormonal contraceptives: pharmacology tailored to women's health
New hormonal contraceptives are safer, have fewer side effects, and offer health benefits for women.
research Efficacy of bergamot: From anti‐inflammatory and anti‐oxidative mechanisms to clinical applications as preventive agent for cardiovascular morbidity, skin diseases, and mood alterations
Bergamot may improve heart health, skin conditions, and mood, but more research is needed to confirm these benefits.
research LabeledIn: Cataloging labeled indications for human drugs
Researchers created LabeledIn, a detailed list of drug uses, showing the importance of human input in making such lists.
research Estimating the Contribution of the Prostate to Blood Dihydrotestosterone
The normal human prostate does not significantly affect blood DHT levels.
research Liposuction and Tumescent Surgery
Tumescent liposuction is safe and effective for different cosmetic surgeries if done within recommended limits.
research Safety and Tolerability of the Dual 5-Alpha Reductase Inhibitor Dutasteride in the Treatment of Androgenetic Alopecia
Dutasteride is safe and effective for treating hair loss, but may decrease libido.
research Androgenic and anti-androgenic effects of progesterone derivatives with different halogens as substituents at the C-6 position
Different halogens on progesterone derivatives can either block or mimic male hormone effects, depending on their type and amount.
research High-performance liquid chromatographic method for the determination of finasteride in human plasma at therapeutic doses
Reliable method detects finasteride in human plasma at low doses.
research Rapid generation of homogenous tumor spheroid microtissues in a scaffold-free platform for high-throughput screening of a novel combination nanomedicine
A new triple drug system using nanoparticles effectively targets breast tumors in 3D models.
research Trastuzumab Induced Chemobrain, Atorvastatin Rescued Chemobrain with Enhanced Anticancer Effect and without Hair Loss-Side Effect
Atorvastatin reversed memory problems caused by cancer drug trastuzumab and improved its cancer-fighting abilities without causing hair loss.
research Addisonian crisis in a young man with atypical anorexia nervosa
A young man with an eating disorder had a life-threatening adrenal crisis due to an autoimmune condition, highlighting the need for better education on managing hormone treatments.
research Development of finasteride polymer microspheres for systemic application in androgenic alopecia
Finasteride microspheres help reduce hair loss for up to eight weeks with fewer side effects.
research Renal Vitamins
Dialysis patients benefit from water-soluble vitamins but need careful management to avoid risks.
research Development and Validation of Androgen-induced Hair Loss and Anagen Induction Mouse Models for Pharmacological Evaluation of Anti-Androgenic Agents
The mouse models are effective for testing new hair loss treatments.
research A regenerative stem cell-derived matrix accelerates functional dermal wound repair in a preclinical diabetic model
A stem cell-derived matrix speeds up healing of diabetic skin wounds.
research Advances in histamine-mediated allergy management: Expanding perspectives on cetirizine’s therapeutic, safety, and toxicological implications
Cetirizine is effective and safe for treating various allergies, with personalized dosing improving its use.
research Netherton Syndrome in a 9-Month-Old Child: Unraveling a Complex Dermatologic Disorder
Early diagnosis and comprehensive management improve life quality for Netherton syndrome patients.
research CECHY KLINICZNE PRZEBIEGU CHORÓB UKŁADU ODDECHOWEGO WYWOŁANYCH PRZEZ SARS-COV-2 U DZIECI Z ZACHODNICH REGIONÓW BIAŁORUSI
Urban children in western Belarus had more severe COVID-19 cases in 2021.
research KINEMATIC ALIGNMENT TECHNIQUE IN TOTAL KNEE ARTHROPLASTY CHANGES FEMORAL SIZING
Kinematic alignment in knee surgery often requires smaller femoral components than mechanical alignment.
research SKUTECZNOŚĆ STOSOWANIA PROBIOTYKÓW ZAWIERAJĄCYCH LACTOBACILLI W LECZENIU ZESPOŁU JELITA DRAŻLIWEGO U DZIECI
Probiotics with Lactobacillus reuteri improve IBS symptoms in children.
research Lichen Planopilaris
Lichen Planopilaris is a hair loss condition best treated early with various medications, including hydroxychloroquine, to prevent permanent baldness.
research Efficacy and safety of omeprazole for severe gastroesophageal reflux in children
Omeprazole effectively treats severe acid reflux in children for short-term use, but long-term safety needs more research.
research Intralesional therapy for the treatment of keratoacanthoma
Intralesional therapy for keratoacanthoma is effective and has fewer side effects than systemic treatments.
research Patient’s experience with subcutaneous and oral methotrexate for the treatment of rheumatoid arthritis
Methotrexate for rheumatoid arthritis often causes side effects like diarrhea, fatigue, and hair loss, especially at higher doses.
research Teriflunomide in multiple sclerosis: an update
Teriflunomide effectively reduces relapses and disability in MS and has a manageable safety profile.
research Effects of a gintonin-enriched fraction on hair growth: an in vitro and in vivo study
Gintonin-enriched fraction promotes hair growth and could be a potential alopecia treatment.