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High LGR5 levels in glioblastoma indicate poor prognosis and are essential for cancer stem cell survival.

The human type II 5α-reductase gene has a specific structure important for understanding certain medical conditions.

The MBTPS2 gene variant c.970+5G>A is a common mutation causing IFAP syndrome.

5α-Reductase helps regulate hormone action in toad testes, especially during breeding season.

BBS7 is crucial for maintaining healthy periodontal ligaments by supporting Shh signaling.

The FGF5 gene determines hair length in dogs.

S100A6 is important for cell functions and can help diagnose and treat diseases.

Different mutations in the 5 alpha-reductase-2 gene were found in affected individuals in the Dominican Republic, suggesting no common ancestry.

A gene called Gk5 controls lipid production in the skin and affects hair growth.

WNT5A contributes to keloid scars by promoting cell changes through specific signaling pathways.

FGF5 gene mutations cause long hair in domestic cats.

Editing the FGF5 gene in sheep increases wool length, confirming its role in hair growth.

The human type II 5α-reductase gene, linked to certain male health conditions, has a specific structure and low similarity to other related genes.

Dock5 is important for skin healing and could help treat diabetic wounds.

Activating TLR5 in the gut can extend lifespan and improve health in aged mice.

5 Alpha-Reductase Inhibitors reduce the effects of testosterone by blocking its conversion into a stronger form.

LGR5 mainly stays inside cells, moving to the trans-Golgi network, and this process is important for its role in cell signaling.

TG5 helps maintain hair follicle health, while TG3 aids in hair shaft development.

A mycobacterial protein shares a similar region with a human skin protein, possibly affecting skin diseases.

The study found nine new hair protein genes in human hair follicles.

Phosphorylation controls TFEB's location in the cell, affecting cell metabolism and stress response.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

The method successfully created stable transfection donor cells for goat hair follicle research.

Steroid 5α-reductase evolved from protists and diversified in eukaryotes, with specific roles in mammals and plants.

New SRD5A2 variants may disrupt protein function, aiding diagnosis and treatment of related disorders.

The system allows precise control of gene expression in mouse skin, useful for studying skin biology.

Testosterone needs to be converted to DHT to reduce stress response in male rats.

The engineered yeast strain BLYAS can quickly and sensitively detect androgenic chemicals.