April 2017 in “Journal of Investigative Dermatology” Stem cells can create hair follicles, potentially treating permanent hair loss, and healthy skin and hair depend on mitochondrial function and special fats.
March 2024 in “Frontiers in genetics” Different types of fibroblasts play specific roles in wound healing and cancer, which could help improve treatments.
Dermal stem cells help regenerate hair follicles and heal skin wounds.
211 citations
,
April 2013 in “Development” More dermal papilla cells in hair follicles lead to larger, healthier hair, while fewer cells cause hair thinning and loss.
January 2025 in “American Journal of Stem Cells” Melanocyte stem cells hold promise for skin regeneration and treating pigmentation issues.
95 citations
,
July 2010 in “Genes & development” Notch/CSL signaling controls hair follicle differentiation through Wnt5a and FoxN1.
67 citations
,
November 2019 in “Nature Communications” Oncogenic melanocyte stem cells can develop into melanoma similar to human cases.
61 citations
,
June 2018 in “Proceedings of the National Academy of Sciences of the United States of America” Light can turn on hair growth cells through a nerve path starting in the eyes.
49 citations
,
October 2009 in “Cancer research” Disrupting Stat3 in hair follicle stem cells greatly reduces skin tumor formation.
10 citations
,
December 2021 in “Frontiers in cell and developmental biology” The research identified genes that explain why some sheep have curly wool and others have straight wool.
9 citations
,
January 2010 in “Journal of the Korean Association of Oral and Maxillofacial Surgeons” Root apical papilla cells from wisdom teeth are best for bone therapies.
June 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Activating β-catenin increases melanocytes and decreases Schwann cells.
1 citations
,
September 2022 in “Morphology” Human stem cells have diverse sources and potential uses in medicine.
February 2024 in “Frontiers in physiology” Hair follicle stem cells help skin heal and grow during stretching.
5 citations
,
May 2023 in “Frontiers in immunology” Environmental factors like diet and vitamin levels, especially Vitamin D, can affect autoimmune diseases differently, with lifestyle changes potentially improving outcomes.
6 citations
,
September 2024 in “Frontiers in Physiology” Overexpression of R-spondin 3 leads to sparse hair and impaired hair regeneration.
4 citations
,
August 2020 in “Applied Materials Today” Hydrogel microcapsules help create cells that boost hair growth.
34 citations
,
November 2010 in “Development” Activating Notch in adult skin causes T cells and neural crest cells to gather, leading to skin issues.
May 2024 in “Cell proliferation” Melatonin helps hair grow by activating a specific signaling pathway.
April 2021 in “Journal of Investigative Dermatology” Leontopodium alpinum extract may help reduce hair shedding by keeping hair in the growth phase longer.
1066 citations
,
March 2010 in “Nature Reviews Molecular Cell Biology” MicroRNAs are crucial in controlling cell signaling, affecting cancer and tissue regeneration.
24 citations
,
April 2012 in “Developmental Biology” Dermal papillae cells, important for hair growth, come from multiple cell lines and can be formed by skin cells, regardless of their origin or hair cycle phase. These cells rarely divide, but their ability to shape tissue may contribute to their efficiency in inducing hair growth.
June 2008 in “Regenerative Medicine” The book explains the science of tissue repair and regeneration, its medical uses, challenges, and ethical concerns.
3 citations
,
November 2023 in “Frontiers in cell and developmental biology” Melanocytes are important for skin and hair color and protect the skin from UV damage.
August 2019 in “Research Square (Research Square)” Certain long non-coding RNAs in cashmere goats affect hair growth when treated with a specific growth factor.
4 citations
,
March 2017 in “Development” Estrogen is important for keeping adult mouse nipple skin healthy by controlling certain cell signals.
3 citations
,
October 2021 in “PLoS ONE” Piperonylic acid speeds up wound healing by reducing inflammation and boosting collagen.
3 citations
,
February 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” Adult esophageal cells can start to become like skin cells, with a key pathway influencing this change.
December 2023 in “Communications biology” Targeting the HEDGEHOG-GLI1 pathway could help treat keloids.
November 2023 in “npj regenerative medicine” Skin spheroids with both outer and inner layers are key for regrowing skin patterns and hair.