research Wounding induces dedifferentiation of epidermal Gata6+ cells and acquisition of stem cell properties
Wounded skin cells can revert to stem cells and help heal.
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research Clinical use of conditioned media of adipose tissue-derived stem cells in female pattern hair loss: a retrospective case series study
ADSC-CM treatment improved hair density and thickness in women with hair loss, safely and effectively.
research Replicative stress, stem cells and aging
Maintaining DNA health in stem cells is key to preventing aging and tissue breakdown.
research Advancements and challenges in stem cell transplantation for regenerative medicine
Stem cell transplantation shows promise for treating diseases but faces challenges like safety, ethics, and cost.
research Biorevitalizing effect of a novel facial serum containing apple stem cell extract, pro‐collagen lipopeptide, creatine, and urea on skin aging signs
The serum improved skin aging signs by enhancing cell metabolism and reducing wrinkles.
research Human Hair Follicle Stem/Progenitor Cells Express Hypoxia Markers
Human hair follicle stem cells show signs of low oxygen levels, which may be important for hair growth and preventing baldness.
research B-Raf and C-Raf Are Required for Melanocyte Stem Cell Self-Maintenance
B-Raf and C-Raf are essential for maintaining melanocyte stem cells to prevent hair graying.
research Stem cells and aberrant signaling of molecular systems in skin aging
Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.
research Roles of Melatonin in Goat Hair Follicle Stem Cell Proliferation and Pluripotency Through Regulating the Wnt Signaling Pathway
Melatonin helps goat hair stem cells grow and maintain their ability to become different cell types.
research Targeted Knockout of β-Catenin in Adult Melanocyte Stem Cells Using a Mouse Line, Dct::CreERT2, Results in Disrupted Stem Cell Renewal and Pigmentation Defects
Removing β-catenin in certain stem cells causes hair whitening and pigmentation issues.
research Stem Cells as a Target for the Delivery of Active Molecules to Skin by Topical Administration
Topical treatments can deliver active molecules to skin stem cells, potentially helping treat skin and hair disorders, including skin cancers and hair loss.
research Niche work when you can get it: collagen XVII and the melanocyte stem cell
Collagen XVII is crucial for preventing hair and pigmentation loss by maintaining melanocyte stem cells.
research Shifting IRES versus Cap-initiated translation during homeostatic stem cell differentiation and stress
Caloric stress and differentiation increase IRES translation, affecting stem cell function and potential therapies.
research Proteomic Analysis of Two Stem Cell Secretomes Used in Combination in a Topical Skin Care Product That Has Demonstrated Efficacy in a Double-Blinded, Vehicle-Controlled Clinical Trial
The combined stem cell secretome in the skin care product effectively reduces inflammation and promotes tissue regeneration.
research Coordinating Stem Cell Behavior in the Hair Follicle
Nfib in hair follicle stem cells boosts melanocyte stem cell growth and differentiation.
research Exploration of Aloe vera, Centella asiatica, Green Tea, and Pueraria mirifica Extracts in Modulating Stem Cell-Like Properties for Hair Rejuvenation Through β-Catenin Stabilization and Activation of the Akt Signaling Cascade in Human Dermal Papilla Cells
Aloe vera, Centella asiatica, Green Tea, and Pueraria mirifica extracts together boost hair growth by enhancing stem cell properties.
research Integrating stem cell biology and organoid technology for skin regenerative therapies
Combining stem cells and organoids could improve skin regeneration treatments.
research Cutaneous Epithelial Stem Cells
Skin and hair renewal is maintained by both fast and slow cycling stem cells, with hair regrowth primarily driven by specific stem cells in the hair follicle bulge. These cells can also help heal wounds and potentially treat hair loss.
research Dermal Microvascular Responses of Human Induced Pluripotent Stem Cell–Derived Skin Organoids to Inflammation and Injury
Skin organoids can mimic human skin responses to injury and inflammation, making them useful for studying skin diseases and testing treatments.
research Current advances in stem cell-based therapies for hair regeneration
Stem cell therapies show promise for hair regrowth but face production and application challenges.
research 3D co-culture model of endothelial colony-forming cells (ECFCs) reverses late passage adipose-derived stem cell senescence for wound healing
A 3D cell model can rejuvenate stem cells to improve wound healing.
research Expression of mesenchymal stem cell marker CD90 on dermal sheath cells of the anagen hair follicle in canine species
CD90 is abundantly present on stem-like cells in dog hair follicles.
research Engineering Hair Follicle Regeneration: Harnessing Stem Cell Technologies, 3D Bioprinting, and Epigenetic Modulation for Precision Therapeutics
Advanced techniques show promise for hair regeneration, but more research is needed for practical use.
research 440 Charting the Spatially Resolved Hair Follicle Stem Cell Niche: A Multi-Omics Atlas of Healthy and Diseased Scalp
Disrupted cell interactions in hair follicles contribute to hair loss in androgenetic alopecia.
research Novel Strategy for Hair Regeneration: Exosomes and Collagenous Sequences of Human a1(XVII) Chain Enhance Hair Follicle Stem Cell Activity by Regulating the hsa-novel-238a-CASP9 Axis
Combining specific proteins and cell-derived particles may help treat hair loss.
research Skin Cell Heterogeneity in Development, Wound Healing, and Cancer
Different types of skin cells play specific roles in development, healing, and cancer.
research FOXN1: A Master Regulator Gene of Thymic Epithelial Development Program
The FOXN1 gene is crucial for developing immune cells and preventing immune disorders.
research Isolation of epithelial stem cells from dermis by a three-dimensional culture system
Researchers isolated a new type of stem cell from mouse skin that can renew itself and turn into multiple cell types.
research Gab1 and Mapk Signaling Are Essential in the Hair Cycle and Hair Follicle Stem Cell Quiescence
Gab1 protein is crucial for hair growth and stem cell renewal, and Mapk signaling helps maintain these processes.
research Development of pluripotent stem cell-derived epidermal organoids that generate effective extracellular vesicles in skin regeneration
Stem cell-derived organoids can improve skin healing.