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GlossaryStem Cell Markers

specific proteins identify and distinguish stem cells from others

Stem cell markers are specific proteins or molecules found on the surface of stem cells that help identify and distinguish them from other cell types. These markers are crucial for researchers and clinicians to isolate, study, and potentially use stem cells in therapies, including treatments for hair loss and alopecia.

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research Stem cell markers (cytokeratin 15, CD34 and nestin) in primary scarring and nonscarring alopecia

54 citations , January 2009 in “British Journal of Dermatology”

Scarring alopecia affects different hair follicle stem cells than nonscarring alopecia, and the infundibular region could be a new treatment target.

research Differential expression of stem cell markers in human follicular bulge and interfollicular epidermal compartments

28 citations , March 2010 in “Histochemistry and Cell Biology”

Different markers are found in stem cells of the scalp's hair follicle bulge and the surrounding skin.

research Distinct expression profile of stem cell markers, LGR5 and LGR6, in basaloid skin tumors

9 citations , January 2017 in “Virchows Archiv”

LGR5 and LGR6 are expressed differently in various skin tumors, which may offer clues about their origins.

research Epidermal retinol dehydrogenases cyclically regulate stem cell markers and clock genes and influence hair composition

April 2024 in “Communications biology”

Enzymes involved in Vitamin A metabolism affect hair growth and type in mice.

research Hair follicle stem cell marker nestin expression in regenerating hair follicles of patients with alopecia areata

6 citations , March 2011 in “European Journal of Dermatology”

Nestin-positive cells are important for hair follicle regeneration in alopecia areata.

research Delayed Cutaneous Wound Healing and Aberrant Expression of Hair Follicle Stem Cell Markers in Mice Selectively Lacking Ctip2 in Epidermis

52 citations , February 2012 in “PloS one”

Lack of Ctip2 in skin cells delays wound healing and disrupts hair follicle stem cell markers in mice.

research From hair to pancreas: transplanted hair follicle mesenchymal stem cells express pancreatic progenitor cell markers in a rat model of acute pancreatitis.

8 citations , January 2021 in “PubMed”

Hair follicle stem cells may help treat acute pancreatitis by reducing inflammation and aiding regeneration.

research Recent progress in hair follicle stem cell markers and their regulatory roles

13 citations , February 2024 in “World Journal of Stem Cells”

New markers help understand and use hair follicle stem cells for regeneration.

LRIG1 as a Positive Prognostic Marker in Merkel Cell Carcinoma and Expression of Epithelial Stem Cell Markers

research LRIG1 is a positive prognostic marker in Merkel cell carcinoma and Merkel cell carcinoma expresses epithelial stem cell markers

10 citations , July 2021 in “Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin”

LRIG1 is linked to better survival in Merkel cell carcinoma.

research Re-Assessing K15 as an Epidermal Stem Cell Marker

36 citations , March 2011 in “Stem Cell Reviews and Reports”

research Behavior of Human Foreskin Keratinocytes Expressing a Hair Follicle Stem Cell Marker CD200

12 citations , November 2007 in “Journal of Investigative Dermatology”

CD200 is not a reliable marker for identifying stem cells in all skin types.

research Expression of mesenchymal stem cell marker CD90 on dermal sheath cells of the anagen hair follicle in canine species

6 citations , September 2009 in “European journal of histochemistry”

CD90 is present on specific cells in dog hair follicles.

research Expression of mesenchymal stem cell marker CD90 on dermal sheath cells of the anagen hair follicle in canine species

15 citations , September 2009 in “European Journal of Histochemistry”

CD90 is abundantly present on stem-like cells in dog hair follicles.

research Markers of Epidermal Stem Cell Subpopulations in Adult Mammalian Skin

96 citations , July 2014 in “Cold Spring Harbor Perspectives in Medicine”

The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.

research Expression of the hair stem cell-specific marker nestin in epidermal and follicular tumors.

35 citations , December 2008 in “PubMed”

Trichilemmoma, BCC, and SCC tumors have different stem cell marker expressions.

Involvement of the Bulge Region with Decreased Expression of Hair Follicle Stem Cell Markers in Senile Female Cases of Alopecia Areata

research Involvement of the bulge region with decreased expression of hair follicle stem cell markers in senile female cases of alopecia areata

20 citations , December 2010 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology”

Decreased CD200 in hair follicles may cause immune issues in some alopecia areata cases.

A Preliminary Study of Markers for Human Hair Follicle Melanin Stem Cells

research A preliminary study of markers for human hair follicle melanin stem cell

1 citations , March 2019 in “Chinese Medical Journal”

Researchers identified potential markers for human hair color stem cells.

research Rat hair follicle-constituting cells labeled by a newly-developed somatic stem cell-recognizing antibody: a possible marker of hair follicle development.

4 citations , February 2013 in “PubMed”

A3 antibody helps identify key cells in rat hair follicle development.

research Progenitor cells expressing nestin, a neural crest stem cell marker, differentiate into outer root sheath keratinocytes

12 citations , July 2019 in “Veterinary Dermatology”

Nestin-expressing progenitor cells become outer root sheath keratinocytes.

research Somatic stem cell heterogeneity: diversity in the blood, skin and intestinal stem cell compartments

137 citations , April 2015 in “Nature Reviews Molecular Cell Biology”

Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.

research Generation and characterization of rat liver stem cell lines and their engraftment in a rat model of liver failure

48 citations , February 2016 in “Scientific Reports”

Researchers created rat liver stem cells that could help repair liver failure in rats and may be useful for studying human liver diseases.

research The HPV16 oncogenes cause aberrant stem cell mobilization

23 citations , May 2013 in “Virology”

HPV16 oncogenes disrupt the normal activity of hair follicle stem cells.

research 09-P006 Epithelial–mesenchymal interactions promote hair follicle neogenesis and a new stem cell niche in adult corneal epithelium

August 2009 in “Mechanisms of Development”

Adult hair follicle cells can create new hair follicles from corneal cells with the right support.

DermaCult Keratinocyte Expansion Medium: A Serum- and BPE-Free Medium Supporting Long-Term Feeder-Free Expansion of Primary Human Epidermal and Pluripotent Stem Cell-Derived Keratinocytes

research 566 DermaCult™ Keratinocyte Expansion Medium, a Serum- and BPE-free Medium Supporting Long-term Feeder-free Expansion of Primary Human Epidermal and Pluripotent Stem Cell-Derived Keratinocytes

November 2022 in “Journal of Investigative Dermatology”

DermaCult™ Keratinocyte Expansion Medium allows human skin cells to grow longer while keeping their ability to develop properly.

research In vitro identification of a stem cell population from canine hair follicle bulge region

5 citations , December 2017 in “Tissue and cell/Tissue & cell”

Researchers found stem cells in dog hair follicles using specific markers.

Exosomes Derived From Umbilical Cord Mesenchymal Stem Cells Promote Hair Regrowth in C57BL/6 Mice Through Upregulation of the RAS/ERK Signaling Pathway

research Exosomes derived from Umbilical cord mesenchymal stem cell promote hair regrowth in C57BL6 mice through upregulation of the RAS/ERK signaling pathway

November 2024 in “Journal of Translational Internal Medicine”

Exosomes from stem cells help hair regrowth by activating a specific signaling pathway.

Stem Cell Identification: In Vivo Lineage Analysis Versus In Vitro Isolation And Clonal Expansion

research The Role of Box A ofHMGB1in Enhancing Stem Cell Properties of Human Mesenchymal Cells: A Novel Approach for the Pursuit of Anti-aging Therapy

1 citations , January 2023 in “In vivo/In Vivo”

Box A of HMGB1 can improve stem cell function, aiding anti-aging therapy.

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Related Terms

Research

research Stem cell markers (cytokeratin 15, CD34 and nestin) in primary scarring and nonscarring alopecia

research Differential expression of stem cell markers in human follicular bulge and interfollicular epidermal compartments

research Distinct expression profile of stem cell markers, LGR5 and LGR6, in basaloid skin tumors

research Epidermal retinol dehydrogenases cyclically regulate stem cell markers and clock genes and influence hair composition

research Hair follicle stem cell marker nestin expression in regenerating hair follicles of patients with alopecia areata

research Delayed Cutaneous Wound Healing and Aberrant Expression of Hair Follicle Stem Cell Markers in Mice Selectively Lacking Ctip2 in Epidermis

research From hair to pancreas: transplanted hair follicle mesenchymal stem cells express pancreatic progenitor cell markers in a rat model of acute pancreatitis.

research Recent progress in hair follicle stem cell markers and their regulatory roles

research LRIG1 is a positive prognostic marker in Merkel cell carcinoma and Merkel cell carcinoma expresses epithelial stem cell markers

research Re-Assessing K15 as an Epidermal Stem Cell Marker

research Behavior of Human Foreskin Keratinocytes Expressing a Hair Follicle Stem Cell Marker CD200

research Expression of mesenchymal stem cell marker CD90 on dermal sheath cells of the anagen hair follicle in canine species

research Expression of mesenchymal stem cell marker CD90 on dermal sheath cells of the anagen hair follicle in canine species

research Markers of Epidermal Stem Cell Subpopulations in Adult Mammalian Skin

research Expression of the hair stem cell-specific marker nestin in epidermal and follicular tumors.

research Involvement of the bulge region with decreased expression of hair follicle stem cell markers in senile female cases of alopecia areata

research A preliminary study of markers for human hair follicle melanin stem cell

research Rat hair follicle-constituting cells labeled by a newly-developed somatic stem cell-recognizing antibody: a possible marker of hair follicle development.

research Progenitor cells expressing nestin, a neural crest stem cell marker, differentiate into outer root sheath keratinocytes

research Somatic stem cell heterogeneity: diversity in the blood, skin and intestinal stem cell compartments

research Generation and characterization of rat liver stem cell lines and their engraftment in a rat model of liver failure

research The HPV16 oncogenes cause aberrant stem cell mobilization

research 09-P006 Epithelial–mesenchymal interactions promote hair follicle neogenesis and a new stem cell niche in adult corneal epithelium

research 566 DermaCult™ Keratinocyte Expansion Medium, a Serum- and BPE-free Medium Supporting Long-term Feeder-free Expansion of Primary Human Epidermal and Pluripotent Stem Cell-Derived Keratinocytes

research In vitro identification of a stem cell population from canine hair follicle bulge region

research Exosomes derived from Umbilical cord mesenchymal stem cell promote hair regrowth in C57BL6 mice through upregulation of the RAS/ERK signaling pathway

research Stem cell identification-in vivo lineage analysis versus in vitro isolation and clonal expansion

research Hair growth-promoting effect of human dermal stem/progenitor cell-derived conditioned medium

research Stem Cell Therapy in Veterinary Dermatology

research The Role of Box A ofHMGB1in Enhancing Stem Cell Properties of Human Mesenchymal Cells: A Novel Approach for the Pursuit of Anti-aging Therapy