January 2022 in “Figshare” Melatonin affects different genes and pathways important for goat hair growth.
February 2011 in “Journal of Investigative Dermatology” New findings suggest targeting IL-23 could treat psoriasis, skin cells can adapt to new roles, direct conversion of skin cells to blood cells may aid cell therapy, removing certain tumor cells could boost cancer immunotherapy, and melanoma may have many tumorigenic cells, not just cancer stem cells.
11 citations
,
February 2021 in “Frontiers in Bioengineering and Biotechnology” Small molecule treatments improve the ability of human amniotic fluid stem cells to become different cell types.
138 citations
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June 2019 in “Stem Cells and Development” Periodontal ligament stem cells show promise for regrowing tissues but require more research for safe, effective use.
411 citations
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April 2010 in “Gastroenterology” Targeting colon cancer stem cells might lead to better treatment results.
December 2024 in “Stem Cell Research & Therapy” ZO-1 helps hair follicle stem cells renew better by changing their structure.
4 citations
,
January 2014 in “Stem Cell Discovery” Stem cells can be reprogrammed for various treatments, but safety and expansion challenges remain.
September 2025 in “Stem Cell Research & Therapy” TAZ boosts fat cell formation in goat stem cells by activating a specific signaling pathway.
6 citations
,
April 2010 in “Cellular Reprogramming” Pig skin cells can turn into mesodermal cells but lose their ability to become neural cells.
35 citations
,
April 2008 in “Human Molecular Genetics” Skin and hair can help us understand organ regeneration, especially how certain stem cells might be used to form new organs.
6 citations
,
June 2012 in “Physiology” The document concludes that more research is needed to understand airway repair and to improve tissue engineering for lung treatments.
125 citations
,
March 2017 in “Micromachines” Microfluidic technology improves cell spheroid creation for better drug testing and tissue engineering.
2 citations
,
December 2011 in “Annales de Dermatologie et de Vénéréologie” 2011 dermatological research found new skin aging markers, hair loss causes, skin defense mechanisms, and potential for new treatments.
TLR2 helps control hair growth and regeneration, and its reduction with age or obesity can impair hair growth.
65 citations
,
December 2000 in “PubMed” The biology of skin and hair is complex and not fully understood.
12 citations
,
September 2024 in “JID Innovations” Skin-on-a-chip devices better mimic human skin for research.
April 2026 in “Research Square” Dapagliflozin helps protect heart cells under stress by improving mitochondrial function and reducing cell damage.
3 citations
,
September 2023 in “Stem Cell Research & Therapy” Researchers successfully differentiated human embryonic stem cells (hESCs) into functional and long-lived melanocytes by transiently expressing JMJD3. These melanocytes maintained their growth rate for approximately 200 days, demonstrated key functions such as melanogenesis and melanin transfer, and showed high engraftability and biocompatibility in immunodeficient mice. The study highlights the potential of using pluripotent stem cells to develop clinical applications for treating pigmentary skin disorders like vitiligo, which affects 0.1–2.0% of the global population. The differentiation protocol's simplicity enhances its potential for clinical use, addressing challenges in obtaining sufficient melanocytes for transplantation.
5 citations
,
April 2021 in “Journal of Mind and Medical Sciences” Fat, bone, and the brain are interconnected in regulating energy and health.
4 citations
,
January 2021 in “Journal of Clinical Medical Research” c-Kit is important for heart regeneration and cancer development.
31 citations
,
September 2020 in “Stem Cell Research & Therapy” Hair follicle stem cells may help repair the brain after a stroke.
April 2017 in “Journal of Investigative Dermatology” Stem cells can create hair follicles, potentially treating permanent hair loss, and healthy skin and hair depend on mitochondrial function and special fats.
27 citations
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June 2013 in “Genes & development” Cav1.2 affects hair growth and could be a target for hair loss treatments.
11 citations
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May 2018 in “Philosophical Transactions of the Royal Society B” New materials help control stem cell growth and specialization for medical applications.
19 citations
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July 2018 in “Mechanisms of Ageing and Development” Eating less can slow aging and help keep stem cells healthy by cleaning out damaged cell parts.
17 citations
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February 2019 in “PubMed” Stem cells can help regenerate hair follicles.
1 citations
,
July 2007 in “Regenerative Medicine” Stem cell research and regenerative medicine have made significant advancements in treating various diseases and conditions.
499 citations
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September 2011 in “Cell” Fat-related cells are important for initiating hair growth.
137 citations
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April 2015 in “Nature Reviews Molecular Cell Biology” Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.
66 citations
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December 2013 in “Nature Cell Biology” Inactive hair follicle stem cells help prevent skin cancer.