research Linking Morphogen and Chromatin in the Hair Follicle
Brg1 is crucial for keeping hair follicle stem cells and repairing skin, working with the Sonic Hedgehog pathway to promote hair growth.
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780-810 / 1000+ results research The Basement Membrane of Hair Follicle Stem Cells Is a Muscle Cell Niche
Nephronectin helps attach muscle cells to hair follicles.
research A Subset of TREM2+ Dermal Macrophages Secretes Oncostatin M to Maintain Hair Follicle Stem Cell Quiescence and Inhibit Hair Growth
Certain immune cells in the skin release a protein that stops hair growth by keeping hair stem cells inactive.
research Embryonic-like regenerative phenomenon: wound-induced hair follicle neogenesis
New hair can grow from large wounds in mice, but less so as they age, involving reprogramming of skin cells and specific molecular pathways.
research Melanocyte Chitosan/Gelatin Composite Fabrication with Human Outer Root Sheath-Derived Cells to Produce Pigment
The technique can isolate cells to help treat skin pigmentation issues.
research TREMendous Macrophages Inhibit Hair Growth
Certain immune cells in the skin can stop hair from growing.
research Advances in genetic and molecular understanding of Omenn syndrome - implications for the future
Newborn screening and gene therapy are expected to improve outcomes for Omenn syndrome patients.
research Molecular Regulation of Secondary Hair Follicle Stem Cell by S100a4 in Cashmere Goat
S100a4 is key for hair growth in cashmere goats.
research Un(MaSC)ing Stem Cell Dynamics in Mammary Branching Morphogenesis
Mammary stem cells drive mammary gland growth by branching and cell mixing.
research Deciphering the molecular mechanisms of stem cell dynamics in hair follicle regeneration
Different stem cells are key for hair growth and health, and understanding their regulation could help treat hair loss.
research Signaling Involved in Hair Follicle Morphogenesis and Development
The conclusion is that proper signaling is crucial for hair growth and development, and errors can lead to cancer or hair loss.
research The roles of Wnt/β‐catenin pathway in tissue development and regenerative medicine
The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.
research Analyses of regenerative wave patterns in adult hair follicle populations reveal macro-environmental regulation of stem cell activity
Hair follicle stem cells are controlled by their surrounding environment.
research Progress in the Development of Stem Cell-Derived Cell-Free Therapies for Skin Aging
Stem cell-derived therapies can help rejuvenate skin by improving wrinkles, elasticity, and pigmentation.
research PBX1-SIRT1 positive feedback loop attenuates ROS-mediated HF- MSC senescence and apoptosis
PBX1 reduces aging and cell death in stem cells by boosting SIRT1 and lowering PARP1.
research Proteomics Characterization of Primary Human Oral Epithelial Cells Using a Novel Culture Technique for Use in Tissue Regeneration
ePUKs could be valuable for regenerative medicine due to their wound healing abilities.
research PBX1-SIRT1 Positive Feedback Loop Attenuates ROS-Mediated HF-MSC Senescence and Apoptosis
Increasing PBX1 reduces aging and cell death in hair follicle stem cells by boosting SIRT1 and lowering PARP1 activity.
research Hair follicle morphogenesis and epidermal homeostasis in we/we wal/wal mice with postnatal alopecia
The we/we wal/wal mice have defects in hair growth and skin layer formation, causing hair loss, useful for understanding alopecia.
research Therapeutic and Clinical Potential of Adipose-Derived Stem Cell Secretome for Skin Regeneration
Adipose-derived stem cell secretome is a promising and effective treatment for skin repair.
research News in brief
Researchers found potential new targets for treating melanoma and nonmelanoma skin cancers, and identified a possible cause and treatment for male pattern baldness and eczema.
research Targeting the Wnt pathways for therapies
Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.
research Stem Cell Therapies for Epidermolysis Bullosa Treatment
Stem cell therapies may help improve symptoms and quality of life for people with epidermolysis bullosa.
research Factors regulating quiescent stem cells: insights from the intestine and other self-renewing tissues
The document concludes that stem cell inactivity is actively controlled and important for tissue repair and balance.
research Developing stratified epithelia: lessons from the epidermis and thymus
The skin and thymus develop similarly to protect and support immunity.
research Japan Strengthens Regenerative Medicine Oversight
Japan improved its regulation of regenerative medicine to ensure safety and prevent unproven treatments.
research Targeted cell delivery of mesenchymal stem cell therapy for cardiovascular disease applications: a review of preclinical advancements
New methods improve stem cell delivery for heart disease, but challenges remain.
research Epigenetic orchestration of RNA m6A methylation in wound healing and post-wound events
m6A methylation is crucial for proper wound healing and tissue repair.
research 1334 Beyond goosebumps: Interactions between the hair follicle, the arrector pili muscle, and the sympathetic nerve during development and hair follicle regeneration
Arrector pili muscle regulates hair follicle stem cells, DNA methylation needed for hair cycling, and Wnt/B-catenin signaling starts hair growth.
research Wound Healing: A Paradigm for Regeneration
Wound healing insights can improve regenerative medicine.
research Stem Cell Use to Treat Dermatological Disorders
Stem cell therapy shows promise for treating skin disorders.