Search

everythinglearnresearchcommunity

for

Search:↓

Some synthesized compounds were more effective than Finasteride in reducing prostate cancer cell growth and androgen levels.

New compounds were made that block an enzyme linked to breast cancer better than existing treatments.

Testosterone and some of its forms can strongly stimulate oil gland growth in skin.

Steroidogenesis inhibitors change but don't stop androgen production in prostate cancer.

The more lipophilic the progesterone derivative, the better it binds to androgen receptors and has antiandrogenic effects.

Steroid hormones are crucial for body functions and have various medical uses, but their misuse can lead to dependence.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

Reconstructed skin models are useful for studying how skin processes certain chemicals.

3α-AdiolG is a good marker for androgen activity in women with excessive hair growth and decreases with anti-androgen treatment.

Certain progesterone derivatives can inhibit enzymes and reduce androgenic activity, potentially affecting prostate growth.

The method reliably profiles eicosanoids and shows epitestosterone reduces their levels, similar to common anti-inflammatory drugs.

Reducing 5α-reductase activity helps endometrial cells differentiate, aiding pregnancy.

Differences in enzyme activity and androgen receptors in hair follicles may explain why hair loss appears differently in men and women.

Male cells need DHT to respond to testosterone, while female cells do not.

Carbamates may help treat androgen-dependent conditions by changing how certain lipid enzymes are produced.

Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.

Smaller substituents at C-17 enhance the inhibitory activity of progesterone derivatives on 5alpha-reductase.

Androgens don't directly affect hair cell growth or protein production.

Prostate cells have proteins that bind to specific hormones, which can increase protein production when activated by these hormones.

The enzyme system in hair follicles is similar to the liver's and is affected by certain inhibitors.

SRD5A1 is crucial in advanced prostate cancer, and blocking both SRD5A1 and SRD5A2 is more effective than targeting SRD5A2 alone.

The P133R mutation in AKR1D1 enzyme causes harmful bile acid buildup, explaining related health issues.

Androgen receptor activity is influenced by hormones, co-factors, modifications, and mutations.

Dihydrotestosterone increases the activity of an enzyme in pubic skin cells that converts testosterone to dihydrotestosterone.

Scientists found out the structure of a human enzyme linked to prostate cancer and hair loss, which could help in designing drugs.

Epitestosterone may act as a weak antiandrogen and can inhibit an enzyme involved in testosterone metabolism.

Affected males are born with ambiguous genitalia, raised as females, but develop male traits at puberty due to enzyme deficiency.

Certain derivatives are more effective 5α-reductase type 2 inhibitors than finasteride.

Androstanediol glucuronide is a reliable marker for hirsutism in women.