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Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.

Sex steroids, especially progesterone, can slow down the growth of mouse melanoma cells.

A new method accurately measures nine steroid hormones in human serum with high sensitivity.

The reconstructed skin model from hair follicles functions like human skin in processing chemicals and can be used to test ingredient safety.

Compound 15a was effective in inhibiting 5α-reductase.

3-tetrazolo steroidal analogs can strongly inhibit the enzyme linked to hair loss.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

Human hair follicles can process steroid hormones like DHEA.

New steroids were patented as effective for treating acne, hair loss, and other conditions related to hormones.

Phytosterols may help manage prostate issues but are less effective than synthetic drugs.

3βHSD2 is not useful for diagnosing PCOS.

Estrogen affects how vitamin A is processed in mouse skin, which may impact acne treatment, hair growth, and skin defense.

Finasteride, when taken daily, lowers dihydrotestosterone levels but doesn't noticeably affect adrenal steroid production, except by blocking the 5 alpha-reductase enzyme.

Curcumin and its derivatives can block an enzyme important for making testosterone, with one derivative being particularly strong.

Different animals have unique versions of the enzyme that changes testosterone into another hormone, which is important for creating effective treatments for prostate and hair loss conditions.

Sex steroid receptors are found in specific skin cells, affecting skin and hair functions.

Estrogens can reduce DHT production in hair follicles, but are less effective than finasteride and progesterone.

Epitestosterone may counteract testosterone's effects and has roles in body processes like prostate growth and hair distribution.

New compounds were made that effectively block a specific enzyme related to androgen conditions.

Mimicking the steroid A-ring may help create effective enzyme inhibitors for prostate disease treatment.

The method accurately measures certain steroids in human hair, showing different levels in males and females.

The document concludes that scientists created various steroids with different properties, including a more effective semi-synthetic vitamin D.

Dexamethasone may influence hair growth by altering estrogen receptor activity in hair cells.

Higher androgen levels and site-specific AR expression cause sex-related skeletal differences, and certain steroids can boost AR expression and androgen effects in bone cells.

Testosterone is made by Leydig cells, is active when not bound to proteins, and works by binding to receptors in muscles and other tissues.

Some new progesterone derivatives are better at blocking testosterone conversion than a common drug.

Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.

A woman's hair loss and other symptoms were due to a rare hormone deficiency treatable with steroids.

Researchers found a gene in hamsters that responds to male hormones and may be indirectly controlled by them.

The research helps understand how finasteride works and aids drug development.