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Steroid-binding globulins have important roles beyond just transporting steroids.

A new method was developed to make a compound used in finasteride and epristeride with a 69% yield.

All five human steroid 5α-reductase enzymes are found in the endoplasmic reticulum.

New methods to make oxasteroids show promise for medical treatments like osteoporosis and breast cancer.

Compound 15a was effective in inhibiting 5α-reductase.

Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.

Inflammation in rheumatoid arthritis increases steroid activation in cells, reducing inflammation.

Androstanediol glucuronide is a reliable marker for hirsutism in women.

Researchers created a new method to measure brain steroids, finding higher levels of certain steroids and changes due to a drug.

A woman's hair loss and other symptoms were due to a rare hormone deficiency treatable with steroids.

Sex and stress steroids quickly change brain cell structures in the hippocampus.

Male hormones control a specific gene in hamster skin, with different hormones having varying effects.

Dexamethasone may influence hair growth by altering estrogen receptor activity in hair cells.

Prostaglandin D2 increases testosterone levels in skin cells through reactive oxygen species, not enzymes, which could lead to new hair loss treatments.

A genetic defect causes males in some Mediterranean populations to be born with ambiguous genitalia and develop male traits at puberty.

Certain mutations in the H6PD gene cause Cortisone Reductase Deficiency by affecting hormone production.

Pig skin cells can turn into mesodermal cells but lose their ability to become neural cells.

During puberty, hormone levels rise, with early increases in some steroids and most menstrual cycles becoming regular by six years after menarche.

Ancient immune and signaling pathways still regulate blood cell development.

Steroid cell tumors in the ovary are rare, can produce testosterone causing symptoms, and are mainly treated with surgery.

The skin produces and processes hormones, affecting both local and overall body functions.

A new compound with strong antiandrogenic effects was found, potentially useful for treating conditions like acne and prostate cancer.

Depressed teens have different steroid levels in urine, which may help identify and treat them.

Neurosteroids may help prevent seizures in epilepsy.

Women with hyperandrogenism have higher androgen levels and lower SHBG, which may contribute to conditions like excessive hair growth and early puberty.

Increased 11β-HSD1 activity in skin may contribute to aging and could be targeted to reduce aging effects.

Testosterone works in different ways, including direct interaction with its receptor, conversion to other hormones for specific effects on genitalia, hair, bones, and muscle, and changes in body fat and sexual function when low.

Different rat and mouse strains respond differently to stress and alcohol, which may help us understand similar human mechanisms.

The study created a new method to test drugs that affect hormone processing in skin.