Search

everythinglearnresearchcommunity

for

Search:↓

The enzyme 17β-HSD type 2 mainly performs oxidation in human sebaceous glands, which may help protect against acne.

Certain gene variations are linked to a higher risk of severe acne, suggesting a genetic influence on the condition.

Enzyme activities do not cause early pubic hair in these girls.

Women with hair loss had higher levels of certain hormones, suggesting a link to a condition like PCOS.

Stress activates a special function of the Vitamin D receptor with the help of c-Jun, which can also prevent cell death.

SRD5A1 is crucial in advanced prostate cancer, and blocking both SRD5A1 and SRD5A2 is more effective than targeting SRD5A2 alone.

Smaller substituents at C-17 enhance the inhibitory activity of progesterone derivatives on 5alpha-reductase.

Prostaglandin D2 increases testosterone production in skin cells through a process involving reactive oxygen species, and antioxidants may help treat hair loss.

Neurosteroids affect prolactin levels in sheep differently depending on stress and pregnancy conditions.

Dihydrotestosterone increases the activity of an enzyme in pubic skin cells that converts testosterone to dihydrotestosterone.

The mineralocorticoid receptor temporarily affects mouse skin development, but the glucocorticoid receptor has a more lasting impact.

3βHSD2 is not useful for diagnosing PCOS.

Stress and alcohol affect brain chemicals differently in rats, mice, and humans, influenced by genetic differences.

Scientists identified three genes important for processing certain brain chemicals, thyroid hormones, and medications.

Dexamethasone reduces inflammation and delays skin cell changes caused by TPA.

Testosterone is made by Leydig cells, is active when not bound to proteins, and works by binding to receptors in muscles and other tissues.

Serum steroid profiling, especially 11-deoxycortisol, helps distinguish between adrenocortical carcinoma and adenoma, considering sex and functional status.

New A-homo-B, 19-dinor steroids showed strong antiandrogenic activity without affecting the enzyme 5α-reductase or androgen receptor binding.

Male hormones indirectly affect skin cell development by increasing growth factor levels from skin fibroblasts.

The human sebocyte culture model has improved understanding of oily skin and acne, and how they can be treated.

Blocking CYP17A1 enzyme may help improve certain brain function issues related to dopamine.

Detecting steroid esters in cattle hair is inconsistent and influenced by sampling factors.

The method can measure multiple steroids in human hair to study long-term steroid metabolism, especially in newborns and children.

TPA strongly increases ODC activity in certain skin cells, potentially aiding tumor growth.

Scientists successfully created and analyzed the structure of a part of the human androgen receptor with specific modulators and a peptide to understand how it binds differently in various tissues.

Liver damage in PCOS is linked to iron overload and cell death due to the miR-761-hepcidin/GPX4 pathway.

The glucocorticoid receptor helps protect skin from tumors and other issues.

Metabolism plays a key role in determining stem cell fate.