1 citations
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February 2013 in “Steroids” Bone mineral and minocycline boost bone cell growth, aiding healing.
The conclusion is that a more comprehensive and precise approach is needed for diagnosing PCOS to address its broader health risks.
3 citations
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October 2021 in “Clinica Chimica Acta” Hormone levels in hair vary across the head, with the highest concentration of a key hormone linked to hair loss at the top.
April 2025 in “Physical and Engineering Sciences in Medicine” PCOS forum users view lifestyle changes and supplements positively, but have mixed feelings about contraceptive pills.
January 2022 in “Current Enzyme Inhibition” New nonsteroidal molecules can potentially increase dihydrotestosterone in neurons by blocking certain enzymes, without affecting prostate and seminal vesicle weight.
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” Early recognition and comprehensive management of PCOS can prevent long-term health issues.
February 2018 in “InTech eBooks” Diagnosing and treating PCOS is complex due to differing criteria and requires a team approach.
October 2013 in “DOAJ (DOAJ: Directory of Open Access Journals)”
31 citations
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January 2003 in “Dermatology” Steroidogenic isoenzymes may help improve treatments for common hair loss.
January 2002 in “HAL (Le Centre pour la Communication Scientifique Directe)” The enzyme system in hair follicles is similar to the liver's and is inhibited by certain substances.
April 2016 in “Journal of The American Academy of Dermatology” Hirsutism and acanthosis nigricans are reliable skin signs of PCOS and suggest the need for further tests for related health issues.
23 citations
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February 2010 in “European Journal of Medicinal Chemistry” January 2005 in “Fuzhou daxue xuebao. Ziran kexue ban” The method is quick and effective for testing steroid 5 alpha-reductase inhibitors.
2 citations
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January 2017 in “Endocrinology” Testosterone and its metabolites have varied effects on different body systems, especially during puberty.
December 2025 in “Cosmoderma” Systemic corticosteroids help manage vitiligo by slowing progression and aiding repigmentation.
13 citations
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June 2017 in “Biochimie open” All five human steroid 5α-reductase enzymes are found in the endoplasmic reticulum.
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” Early recognition and comprehensive management of PCOS can prevent long-term health issues.
January 2025 in “International Journal of Forest Animal and Fisheries Research” DHEA may play a complex role in PCOS, affecting hormones, metabolism, and symptoms.
July 2024 in “Reactions Weekly”
5 citations
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December 2004 in “Dermatology” Two women with very high androgen levels had only slight skin issues, one due to a non-classical adrenal disorder and the other due to an adrenal tumor.
1 citations
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January 1989 in “Carcinogenesis” Dexamethasone reduces inflammation and delays skin cell changes caused by TPA.
May 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” The enzyme 5α-reductase is important for proper blood vessel development during the fertility-related transformation of the uterus lining.
August 2021 in “Pediomaternal Nursing Journal” Endocrine therapy helps with reproductive and metabolic issues in women with PCOS.
July 2024 in “Journal of Investigative Dermatology” July 2024 in “Journal of Investigative Dermatology” The new skin organoid system effectively mimics human skin for studying its functions, injuries, and diseases.
7 citations
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September 2014 in “Journal of Obstetrics and Gynaecology Research” Ultrasound measurement of the ovarian stroma to total area ratio is not a reliable single predictor of high male hormone levels in Thai women with PCOS, but works better when combined with clinical signs.
219 citations
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January 2006 in “Drug Metabolism Reviews” DHEA affects multiple receptors and may help with metabolic issues, but its safety and effectiveness in humans are unclear.
5 citations
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July 2025 in “Endocrine” 8 citations
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March 2012 in “Mass spectrometry letters” The S9 fraction with GC-IDMS is effective for measuring 5α-reductase activity.
November 1978 in “PubMed” Antiandrogenic treatments can effectively manage certain skin conditions by using female hormones.