1 citations
,
June 2023 in “Cureus” Spironolactone may help improve symptoms and tear quality in dry eye disease.
21 citations
,
March 1982 in “JAMA” Spironolactone is effective and safe for treating excessive facial hair in women.
5 citations
,
September 2011 in “Bioorganic & Medicinal Chemistry Letters” Pfizer found that pantolactam-based compounds can reduce sebum (skin oil) production when applied topically.
44 citations
,
June 1985 in “Fertility and sterility” Combination drug therapy is effective for hirsutism that doesn't improve with just one medication.
26 citations
,
March 2018 in “Experimental Dermatology” Prolactin may influence skin glands and could be a target for treating acne and skin aging.
February 2018 in “Zenodo (CERN European Organization for Nuclear Research)” High doses of Lagenaria siceraria fruit powder lower FSH and LH hormone levels in male rats.
Oral spironolactone may be effective for female pattern hair loss with a low rate of side effects.
14 citations
,
August 2015 in “Endocrinology” The antibody 005-C04 blocks prolactin receptors, causing reversible infertility, impaired lactation, and hair regrowth in female mice.
1 citations
,
November 2020 in “Journal of The American Academy of Dermatology” GSK-36 downregulation with UTMD improves plaque stability in atherosclerosis treatment.
April 2016 in “Journal of The American Academy of Dermatology” Spironolactone use is not linked to an increased risk of breast cancer, but caution is advised for high-risk patients.
July 2020 in “Journal of the American Academy of Dermatology” Spironolactone does not increase the risk of breast cancer recurrence.
February 2025 in “medRxiv (Cold Spring Harbor Laboratory)” GLP-1 agonists may increase the risk of hair loss.
23 citations
,
July 1979 in “Canadian journal of biochemistry” Spironolactone reduces the number of androgen receptor sites in rat skin by blocking them with its metabolite.
162 citations
,
August 2002 in “Survey of Ophthalmology” Latanoprost can make eyelashes longer, thicker, and darker.
January 2026 in “Frontiers in Pharmacology” Wedelolactone may help treat inflammation, infections, cancer, bone loss, and organ damage.
23 citations
,
July 1989 in “Postgraduate medical journal” Spironolactone did not make hair thinner in women with excess hair growth.
September 2024 in “Advanced medical journal” Spironolactone is effective and safe for treating acne in women, especially those over 25 with hormonal imbalances.
18 citations
,
September 2021 in “Colloids and surfaces. B, Biointerfaces” Nanoparticles can effectively deliver spironolactone to hair follicles for treating alopecia and acne.
6 citations
,
October 2015 in “Clinical Case Reports” A woman with acromegaly experienced severe hair loss from a drug called Lanreotide Autogel, which improved after stopping the treatment.
5 citations
,
July 2014 in “Actas dermo-sifiliográficas/Actas dermo-sifiliográficas” Latanoprost eye drops caused excessive hair growth and eyelash whitening in a woman.
17 citations
,
August 2001 in “Australasian journal of dermatology” A woman's liver problems improved after she stopped taking spironolactone.
March 2020 in “Revista Eletrônica da Faculdade de Ceres” Latanoprost's effectiveness for hair growth is not confirmed but shows promise, needing more research.
7 citations
,
January 1990 Spironolactone improved hair density and quality in women with hair loss.
May 2025 in “Animal Bioscience” Inhibiting prolactin reduces hair follicle activation in cashmere goats.
December 2025 in “Current Issues in Molecular Biology” New steroid compounds may help with hormonal therapy and have potential benefits for glucose disorders, but more research is needed.
1 citations
,
January 2015 in “Actas dermo-sifiliográficas/Actas dermo-sifiliográficas” Latanoprost eye drops caused excessive cheek hair growth and eyelash whitening in a woman.
40 citations
,
March 2003 in “The journal of small animal practice/Journal of small animal practice” Trilostane helped a dog with an adrenal tumor feel better and stay healthy.
3 citations
,
July 1990 in “Acta dermato-venereologica” A man's baldness improved possibly due to a medication that blocks male hormones.
January 2006 in “Xibei zhiwu xuebao” Norethindrone and levonorgestrel can enhance or inhibit root growth in Arabidopsis thaliana depending on the concentration.
February 2026 in “JAAD International”