August 2025 in “International Journal of Scientific Research in Biological Sciences” Higher levels of DHEA and TNF-α are linked to PCOS symptoms.
August 2025 in “DS Reviews of Research in Life Sciences” Women with PCOS have higher levels of DHEA, IL-6, and TNF-α.
67 citations
,
February 2010 in “Acta Obstetricia et Gynecologica Scandinavica” Hirsutism is a strong sign of high male hormones and metabolic problems in women with PCOS, but acne and hair loss are not.
7 citations
,
January 2024 in “Medicinska istrazivanja” PCOS causes hormonal imbalances, irregular periods, and can lead to infertility, obesity, and mental health issues.
4 citations
,
November 2012 in “Obstetrics, Gynaecology & Reproductive Medicine” Lifestyle changes and clomiphene are first-line treatments for infertility in women with PCOS, with other options available if these fail.
2 citations
,
January 2013 in “Elsevier eBooks” The chapter explains the causes of excessive hair growth and masculinization in women and how to measure hormone levels related to these conditions.
212 citations
,
May 2010 in “American Journal of Obstetrics and Gynecology” Diagnosing PCOS in teenagers is challenging and should use strict criteria to avoid misdiagnosis and unnecessary worry.
4809 citations
,
January 2004 in “Fertility and Sterility” The 2003 consensus updated PCOS diagnosis criteria and highlighted increased risks of diabetes and heart disease for those affected.
3 citations
,
June 2025 in “Drug Design Development and Therapy” Targeting glycolysis may help treat PCOS by improving insulin sensitivity and ovarian function.
November 2013 in “John Wiley & Sons, Ltd eBooks” The document concludes that accurate diagnosis of male and female gonadal disorders is crucial for effective treatment and better patient outcomes.
59 citations
,
August 2007 in “Clinical Endocrinology” The current methods for diagnosing polycystic ovary syndrome are too vague and may lead to misdiagnosis and problems in research.
31 citations
,
January 2018 in “Pediatric annals” Early adrenal gland maturation in young children can be normal, but other serious conditions should be ruled out first.
15 citations
,
January 1988 in “Drugs” The document concludes that treatments for female hair loss and excessive hair growth are temporary and not well-studied.
1 citations
,
July 2015 in “AACE clinical case reports” Removing both ovaries treated the woman's excess male hormone symptoms.
7 citations
,
March 2023 in “Gynecological Endocrinology” After tumor removal, the woman regained normal hormone levels, menstruated, and had a healthy baby.
November 2023 in “JCEM Case Reports” A postmenopausal woman's excess male hormone symptoms improved after her ovaries were removed.
7 citations
,
January 2022 in “Case Reports in Endocrinology” Ovarian hyperthecosis can cause symptoms even with normal testosterone levels, and surgery can improve these symptoms.
2 citations
,
July 2023 in “AACE Clinical Case Reports” Ovarian vein sampling can effectively locate ovarian tumors when imaging is unclear.
January 2025 in “JCEM Case Reports” Ovarian thecomas can cause virilization in postmenopausal women and are treated with surgery.
1 citations
,
September 2020 in “Endocrinology, Diabetes & Metabolism Case Reports” The conclusion is that thorough investigation of hypertension and hormonal dysfunctions is important, and there may be a link between these conditions and cancer.
April 2020 in “Journal of the Endocrine Society” An ovarian tumor caused a woman's male-like symptoms, which improved after surgery.
55 citations
,
May 2019 in “Journal of Endocrinology” Androgens are important for female fertility and could help in IVF treatment, but also play a role in causing PCOS.
53 citations
,
April 2016 in “Stem cell research & therapy” LL-37 helps stem cells grow and move, aiding tissue regeneration and hair growth.
5 citations
,
April 2024 in “Journal of Ovarian Research” miR-21 helps improve ovarian function recovery in treated mice.
March 2026 in “JCEM Case Reports” Surgery removed ovarian tumors, normalizing testosterone and improving symptoms.
December 2024 in “AACE Clinical Case Reports” Ovarian hyperthecosis can cause polycythemia, and surgery can normalize symptoms.
October 2024 in “Journal of the Endocrine Society” Ovarian steroid cell tumors can mimic adrenal hyperplasia, and surgery can normalize hormone levels.
October 2024 in “Journal of the Endocrine Society” Early detection of ovarian steroid cell tumors is crucial to prevent lasting symptoms.
31 citations
,
June 2022 in “Stem Cell Research & Therapy” CD146 + mesenchymal stem cells are more effective for treating premature ovarian failure.
10 citations
,
March 2016 in “The Journal of Obstetrics and Gynecology of India” The article suggests renaming Polycystic Ovarian Syndrome (PCOS) to "Hyperandrogenic Persistent Ovulatory Dysfunction Syndrome" (HA-PODS) for accuracy and consistency, but no final decision was made.