research Non-canonical dimerization of the androgen receptor and other nuclear receptors: implications for human disease
Mutations in certain receptors can cause diseases and offer new treatment options.
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research A machine learning and network framework to discover new indications for small molecules
A machine learning model called CATNIP can predict new uses for existing drugs, like using antidepressants for Parkinson's disease and a thyroid cancer drug for diabetes.
research Rapid Characterization of the Functional and Pharmacological Consequences of Cantú Syndrome KATPChannel Mutations in Intact Cells
Kir6.1 mutations in Cantú syndrome increase channel sensitivity and hyperpolarization, while SUR2B mutations do not.
research Sexual dimorphism of COVID-19 inspires drug repositioning and host-targeting immunotherapy for viral pneumonia
Balancing testosterone may reduce COVID-19 severity.
research Recent advances in cellulose nanocrystals-based sensors: A review
Cellulose nanocrystals are promising for making effective, sustainable sensors for various uses.
research Hair cosmetics: An overview
Dermatologists need to understand hair products to treat hair and scalp issues better.
research Nanocosmetics: performance enhancement and safety assurance
Nanotechnology improves cosmetics' effectiveness and safety.
research MoS2 Nanoclusters-based biomaterials for disease- impaired wound therapy
The SA-MS hydrogel is a promising material for improving wound healing and skin regeneration in diseases like diabetes and skin cancer.
research Development and evaluation of finasteride loaded ethosomes for targeting to the pilosebaceous unit
Finasteride-loaded ethosomes improve hair loss treatment by targeting pilosebaceous unit.
research MEGA PROTAC, MEGA DOCK-based PROTAC mediated ternary complex formation pipeline with sequential filtering and rank aggregation
MEGA PROTAC improves prediction and ranking of protein complexes better than existing methods.
research Melanocyte Chitosan/Gelatin Composite Fabrication with Human Outer Root Sheath-Derived Cells to Produce Pigment
The technique can isolate cells to help treat skin pigmentation issues.
research Sebum Production
Sebum production varies by individual and is influenced by age, gender, and hormones, affecting skin and hair health.
research IMMUNOLOGICAL AND SOME BIOLOGICAL BIOMARKERS INVESTIGATION IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS
No single biomarker is reliable enough for diagnosing and assessing SLE.
research Understanding the biochemical properties of human hair keratins : self-assembly potential and cell response
Human hair keratins can self-assemble and support cell growth, useful for biomedical applications.
research Efficacy and safety evaluations of topical proretinal nanoparticles
Proretinal nanoparticles are a safe and effective way to deliver retinal to the skin.
research Plants used in cosmetics
Natural products in cosmetics are beneficial for skin and hair care with low toxicity.
research Androgen Signaling Regulates SARS-CoV-2 Receptor Levels and Is Associated with Severe COVID-19 Symptoms in Men
Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.
research SOX11 and SOX4 drive the reactivation of an embryonic gene program during murine wound repair
SOX11 and SOX4 help skin cells act like embryonic cells to heal wounds in mice.
research Evaluation and diagnosis of the hair loss patient
To diagnose hair loss, use a systematic approach including history, exams, and tests.
research A novel mouse model demonstrates that oncogenic melanocyte stem cells engender melanoma resembling human disease
Oncogenic melanocyte stem cells can develop into melanoma similar to human cases.
research Valence-engineered catalysis-selectivity regulation of molybdenum oxide nanozyme for acute kidney injury therapy and post-cure assessment
Molybdenum oxide nanozymes can effectively treat and monitor acute kidney injury by reducing oxidative stress.
research Treatment of Male Pattern Baldness with Botulinum Toxin: A Pilot Study
Botox increased hair count in men with baldness and might work by improving scalp blood flow.
research The cultural and philosophical concepts of cosmetics in beauty and art through the medical history of mankind
Cosmetics enhance beauty, fix defects, and intimidate enemies, with varying cultural standards and alternative methods.
research Development and characterization of phyto-vesicles of β-sitosterol for the treatment of androgenetic alopecia
Phyto-vesicles of β-sitosterol may effectively treat hair loss.
research Exogenous Factors in Hair Disorders
Outside factors like grooming, chemicals, and the environment can damage hair and cause disorders.
research Deficiency of the human cysteine protease inhibitor cystatin M/E causes hypotrichosis and dry skin
Lack of cystatin M/E causes thin hair and dry skin.
research Tracing selection signatures in the pig genome gives evidence for selective pressures on a unique curly hair phenotype in Mangalitza
Selective breeding caused the unique curly hair in Mangalitza pigs.
research Transcriptomics analysis reveals molecular alterations underpinning spaceflight dermatology
Spaceflight can harm skin health by altering gene expression, affecting DNA, mitochondria, and skin barriers.
research GC–MS profiling and in silico prediction of MAPK receptor activation by fatty acids of watercress oil for hair growth marketed in Saudi Arabia
Watercress oil may promote hair growth by activating specific receptors.
research Protein kinase C is a key target for attenuation of Leigh syndrome by rapamycin
Rapamycin may help treat Leigh syndrome by targeting protein kinase C.