research Finasteride inhibits the disease-modifying activity of progesterone in the hippocampus kindling model of epileptogenesis
Finasteride worsens seizures in epilepsy rats and speeds up epileptogenesis in mice.
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research STUDIES ON THE ANTIMICROBIAL ACTIVITY OF EVOLVULUS ALSINOIDES, MURRAYA KOENIGII, LAWSONIA INERMIS, HIBISCUS ROSA-SINENSIS, AZADIRACHTA INDICA AGAINST MALASSEZIA FURFUR USING FRACTIONAL FACTORIAL DESIGN
The study found that a specific combination of five medicinal plants effectively inhibits the fungus that causes dandruff.
research Inhibition of Rat 5α-Reductase Activity and Testosterone-Induced Sebum Synthesis in Hamster Sebocytes by an Extract ofQuercus acutissimaCortex
An extract from Quercus acutissima bark was found to reduce sebum production and block an enzyme linked to acne.
research Foxp3 Post-translational Modifications and Treg Suppressive Activity
Changes to the Foxp3 protein affect how well regulatory T cells can control the immune system, which could help treat immune diseases and cancer.
research Responses of hair follicle–associated structures to loss of planar cell polarity signaling
Loss of Fz6 disrupts hair follicle and associated structures' orientation.
research Hoxc13/β-catenin Correlation with Hair Follicle Activity in Cashmere Goat
Hoxc13 is linked to seasonal hair growth in Cashmere goats and is affected by melatonin.
research Scaled Quantum Chemical Studies of the Molecular Structure and Vibrational Spectra of Minoxidil
The analysis shows where minoxidil's atoms are likely to react and describes its electronic transitions and behavior with temperature changes.
research Evidence of the moderating role of hair cortisol and hair cortisone in the relationship between work stress and depression symptoms among Chinese fishermen
Hair cortisol and cortisone levels may affect how work stress influences depression in Chinese fishermen.
research Procyanidin B-2 and the hair-growing activity of proanthocyanidins
Procyanidin B-2 from apple juice significantly increases hair growth and may be more effective than minoxidil without side effects.
research Continuous Dynamics of The Hair Follicle: Spiral Model for Understanding Follicular Activity Throughout Life
The Spiral Model helps understand hair growth changes with age and identify hair problems early.
research Enhancing hair regeneration: Recent progress in tailoring nano-structured lipid carriers through surface modification strategies
Surface-modified nanostructured lipid carriers can improve hair growth treatments.
research Hardwiring Stem Cell Communication through Tissue Structure
The conclusion is that tissue structure is key for stem cell communication and maintaining healthy tissues.
research An Overview of Herbal Ingredients with Anti-dandruff Activity in Shampoo Formulations
Some herbal ingredients like linalool and tea tree oil have anti-dandruff properties and are safe for use in shampoos.
research Effect of neurosteroid dehydroepiandrosterone on the higher nervous activity of old non-human primates
DHEA improved brain function and behavior in old monkeys and had additional health benefits.
research Vitamin D and the skin: Focus on a complex relationship: A review
Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.
research Pharmacological and Histochemical Screening for Hair Growth-Promoting Activity of Daucus carota Herbal Gel.
Carrot extract in gel form may help hair grow better.
research Effect of drying conditions on the chemical compositions, molecular docking interactions and antioxidant activity of Hedychium spicatum Buch.-Ham. Rhizome essential oil
Oven drying at 30°C gives the best essential oil yield and antioxidant activity for Hedychium spicatum rhizomes.
research FINASTERIDE INHIBITS 5?-REDUCTASE ACTIVITY IN HUMAN DERMAL FIBROBLASTS: PREDICTION OF ITS THERAPEUTIC APPLICATION IN ANDROGEN-RELATED SKIN DISEASES
Finasteride helps treat skin issues like acne and baldness by blocking testosterone conversion.
research Bioactives in Chinese Proprietary Medicine Modulates 5α-Reductase Activity and Gene Expression Associated with Androgenetic Alopecia
Chinese medicine may help treat hair loss by affecting genes and enzyme activity.
research In vitro and in silico evaluation of toxicological and anti-proliferative activity in phytochemical compounds of several solvent extracts from Zaleya pentandra L
Zaleya pentandra extracts, especially acetone, may be useful for new medicines and food industry applications.
research <p>Asian Hair: A Review of Structures, Properties, and Distinctive Disorders</p>
Asian hair is generally straight and thick, with unique disorders and properties, and more research is needed to understand it fully.
research Determination of Secondary Follicle Characteristics, Density, Activity, and Hoxc13 Expression Pattern of Hexi Cashmere Goats Breed
Hexi cashmere goats' hair growth varies by stage, with Hoxc13 linked to hair activity.
research Runx1 Role in Epithelial and Cancer Cell Proliferation Implicates Lipid Metabolism and Scd1 and Soat1 Activity
Runx1 controls fat-related genes important for normal and cancer cell growth, affecting skin and hair cell behavior.
research Multiple readout assay for hormonal (androgenic and antiandrogenic) and cytotoxic activity of plant and fungal extracts based on differential prostate cancer cell line behavior
The study created a test that found hormonal and toxic effects in plant and fungal extracts using prostate cancer cells.
research Antidepressant-like effect of fluoxetine may depend on translocator protein activity and pretest session duration in forced swimming test in mice
Fluoxetine's effectiveness as an antidepressant in mice depends on a specific protein activity and a 5-minute pretest.
research Extracellular vesicles derived from embryonic day 13 fetal mouse dermal fibroblasts exhibit potential antifibrotic activity
The study explores the antifibrotic potential of extracellular vesicles (EVs) from embryonic day 13 (E13) fetal mouse dermal fibroblasts. These EVs were effective in suppressing fibrotic activation in both E17 fascia fibroblasts and human keloid-derived fibroblasts, which are linked to scarring and fibrosis. In contrast, EVs from E17 and adult fibroblasts increased fibrotic responses. The findings suggest that E13 dermal fibroblasts have intrinsic antifibrotic properties transferable via EVs, offering potential therapeutic strategies for human scars and fibrotic skin diseases. The study also notes the importance of determining the optimal EV dosage, as higher doses may not achieve the desired antifibrotic effects. Despite challenges in large-scale collection and potential risks in human therapy, E13-derived EVs show promise for future antifibrotic treatments, emphasizing the need to identify specific antifibrotic factors within these EVs.
research Serum 25-Hydroxy Vitamin D Level in Patients with Alopecia Areata and Its Relationship with Severity of the Disease
Lower vitamin D levels are linked to more severe alopecia areata.
research Avicequinone C Isolated from Avicennia marina Exhibits 5α-Reductase-Type 1 Inhibitory Activity Using an Androgenic Alopecia Relevant Cell-Based Assay System
Avicequinone C, a compound found in the Avicennia marina plant, can reduce hair loss by inhibiting a hormone linked to androgenic alopecia.
research Geranylated Coumarins From Thai Medicinal Plant Mammea siamensis With Testosterone 5α-Reductase Inhibitory Activity
Compounds from the plant Mammea siamensis may help treat hair loss.
research Transient Ca2+ entry by plasmalogen-mediated activation of receptor potential cation channel promotes AMPK activity
Plasmalogens activate a channel in cells that may stimulate hair growth.