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Neurosteroids and benzodiazepines reduce neuron excitability, with lasting effects on inhibitory neurons.

11β-Hydroxylase inhibitors help prevent seizures in mice by boosting natural neurosteroid production.

Some newly made compounds can block an enzyme linked to hair loss and prostate growth, with one in particular being very selective.

Cepharanthine may help treat COVID-19 by targeting multiple pathways.

A specific enzyme that activates the hair growth medication minoxidil when applied to the skin was identified.

Sexually transmitted infections and HIV should be considered as possible causes of chronic diarrhea, especially in men who have sex with men.

Compound 1 showed promising anticancer activity.

Neuroactive steroids affect cocaine's rewarding effects through the ς₁ receptor.

Overexpressing SSAT enzyme reduces prostate tumor growth in mice.

Allopregnanolone is needed for certain brain processing issues caused by D1 dopamine receptor activation.

Created finasteride complex to increase water solubility and drug release.

An older woman had false beliefs after taking a depression medication, which stopped when she stopped the medication.

In 2002, various drugs caused serious side effects, including vitamin B12 deficiency, heart issues, blindness, hypersexuality, allergic reactions, blood clotting problems, pupil dilation, capillary leak syndrome, muscle breakdown, hepatitis, skin reactions, and lupus.

The NUDT15 R139C variant causes thiopurine-induced leukocytopenia through a different mechanism than previously thought in Japanese patients with inflammatory bowel disease.

Cubosomal gels enhance skin absorption of cetirizine better than niosomal gels.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

HIV medication ritonavir can increase the effects of nasal sprays like fluticasone, causing Cushing's syndrome.

A person with a new mutation in the SCN1A gene developed brain inflammation after COVID-19.

Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.

Researchers found a specific immune receptor in patients that causes severe skin reactions to a drug.

Finasteride raises suicide-linked aggression and stops clozapine's positive effects in schizophrenia animals.

A brominated phenoxy compound effectively inhibits a human enzyme and shows potential for clinical use.

Sodium valproate caused vomiting in 20% of children under 2 years old, with other side effects like hair loss and loss of appetite also noted.

A new compound was effective for imaging prostate cancer in rats.