research Development and Characterization of Thiolated Cyclodextrin-Based Nanoparticles for Topical Delivery of Minoxidil
Thiolated cyclodextrin-based nanoparticles effectively deliver Minoxidil for scalp treatment without causing skin irritation.
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research Age-related downregulation of dihydrotestosterone-inactivating enzymes in human scalp sebaceous glands
Age-related changes in scalp glands may affect hair health, but sulforaphane might help.
research Carbonylation of hair proteins: A robust biomarker of molecular and structural oxidative damage in hair fibres
Protein carbonylation is a sensitive marker for oxidative damage in hair, especially from light exposure.
research Dyeing behaviours of amino heterocyclic compounds as blue oxidative hair dye precursors applied to keratin fibres
1,2,3,4-tetrahydroquinoline compounds are great for stable, pure blue hair dye.
research Investigation of pH effect on cationic solute binding to keratin and partition to hair
Solute binding to hair keratin is mainly driven by hydrophobic interactions and changes with pH.
research Protective effect of conditioner agents on hair treated with oxidative hair dye
Conditioners in hair dye reduce damage and improve combability.
research Hair perming via thiol‐Michael click reaction: A strategy to avoid oxidative damage
A new hair perming method avoids damage and lasts longer than traditional methods.
research Androgen binding to cytosol and nuclei of hamster sebaceous glands
Dihydrotestosterone specifically binds to hamster sebaceous glands, with a higher affinity than testosterone.
research SOCS1 and SOCS3 as key checkpoint molecules in the immune responses associated to skin inflammation and malignant transformation
SOCS1 and SOCS3 help control skin inflammation and are important for developing treatments for skin diseases.
research DSC-investigations of alpha-keratins and the specific effects of chemical treatments on human hair
Chemical treatments weaken hair's thermal stability and structure.
research Hair Preparations
Hair care products are regulated, with shampoos, conditioners, dyes, and styling products designed for cleaning, enhancing, and maintaining hair.
research THE IDENTIFICATION OF MOLECULAR MECHANISMS FROM BIOACTIVE COMPOUNDS IN Sansevieria trifasciata PLANT AS ANTI-ALOPECIA: In-Silico APPROACH
Compounds from the Sansevieria trifasciata plant might be effective for treating hair loss.
research Synthesis and Evaluation of 2‘-Substituted 4-(4‘-Carboxy- or 4‘-carboxymethylbenzylidene)-N-acylpiperidines: Highly Potent and in Vivo Active Steroid 5α-Reductase Type 2 Inhibitors
Compounds 15, 20, and 25 are strong inhibitors of human steroid 5α-reductase type 2.
research Understanding the formation mechanism of drug-polymer inclusion complex by structure elucidation and theoretical calculation
The research found how certain drugs and polymers form stable complexes, which could help develop new pharmaceutical forms.
research hKAP1.6 and hKAP1.7, Two Novel Human High Sulfur Keratin-Associated Proteins are Expressed in the Hair Follicle Cortex
Two new proteins, hKAP1.6 and hKAP1.7, are found in the hair follicle cortex.
research Cyclohex-1-ene Carboxylic Acids: Synthesis and Biological Evaluation of Novel Inhibitors of Human 5α Reductase
Scientists made new substances that can block an enzyme linked to prostate issues and hair loss, with potential for creating a new treatment.
research Influence of functionalized silicones on hair fiber–fiber interactions and on the relationship with the macroscopic behavior of hair assembly
Functionalized silicones improve hair appearance, combing, and manageability.
research Hair Conditioners*
Some nutrients and antioxidants may improve skin and hair health, but more research is needed to confirm these benefits.
research Effect of antioxidants in protecting chemically damaged hair
This study investigated the protective effects of antioxidants, specifically ferulic acid and resveratrol, on chemically damaged hair. Using standardized bleached Caucasian hair strands, the research involved two stages: treatment with oxidative hair dye containing antioxidants and application of leave-in conditioners with antioxidants followed by simulated solar exposure. The results showed that both antioxidants effectively protected hair fibers, increasing denaturation energy by up to 35% and reducing protein loss compared to untreated hair. While they did not prevent cysteine oxidation during dyeing, they significantly reduced cysteine oxidation by about 50% during solar exposure. The study concludes that incorporating ferulic acid or resveratrol in cosmetic formulations effectively protects hair from oxidative damage caused by chemical processes and sun exposure.
research The Oxidative Degradation of Keratin (Wool and Bovine Hair)
Oxidizing agents break down keratin in wool and hair, causing swelling and increased solubility.
research 1331 Glutathione (GSH) distribution by quantitative MALDI imaging in reconstructed human skin upon activation of GSH biosynthesis by Nrf2 pathway activator
Resveratrol activates the Nrf2 pathway in human skin, significantly increasing the production and distribution of the antioxidant glutathione.
research Purification and characterization of rat liver minoxidil sulphotransferase
Enzyme purified and characterized for minoxidil sulphation in rat liver.
research Human stratified squamous epithelia differ in cellular fatty acid composition
Fatty acid composition in human skin, mouth, and hair cells varies with keratinization, and cultured cells show essential fatty acid deficiency.
research Glutathione-S-epoxide transferase in human hair follicles
GSH-T levels in hair follicles are similar in smokers and non-smokers and don't increase with certain treatments.
research Disorders of the skin appendages
The document concludes that proper recognition and treatment of skin appendage disorders are important for management.
research The role of cell–cell and cell–matrix junctional complexes in sebaceous gland homeostasis and differentiation
Cell junctions are crucial for healthy skin by supporting sebaceous gland function and sebum production.
research In-Vitro Release of Zinc Pyrithione from A Shampoo Base and the Effects of Various Additives on its Release Rate
Additives like ethanol and propylene glycol increase the release of zinc pyrithione from shampoo.
research Characterization of the proteins of guinea-pig hair and hair-follicle tissue
Guinea-pig hair and follicle proteins are mostly similar, but follicles have more group 2 proteins and fewer group 3 and 4 proteins.
research A review on phytochemical, ethnomedical and pharmacological studies on genus Sophora, Fabaceae
The genus Sophora has compounds with potential health benefits and could lead to new drugs, but more research is needed to understand their effects and safety.
research Hair coat characteristics in Friesian heifers in the Netherlands and Kenya : experimental data and a review of literature
Friesian heifers take about 18 months to adapt to Kenya's climate, with hair changes not strongly linked to weight gain.