January 2014 in “Journal of Physiology & Pathology in Korean Medicine” Microneedle roller therapy can help hair grow.
October 2025 in “Pharmaceutics” Microneedles improve drug delivery for skin diseases, enhancing treatment effectiveness and patient compliance.
Microneedling and PRP are generally safe but can cause mild skin issues; serious problems are rare.
91 citations
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August 2024 in “Acta Pharmaceutica Sinica B” Microneedles can improve skin disease treatment by delivering drugs directly through the skin.
2 citations
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August 2022 in “Aesthetic Plastic Surgery” October 2024 in “Aesthetic Plastic Surgery” February 2023 in “Aesthetic Plastic Surgery” April 2026 in “Journal of Cosmetic Dermatology” Microneedling with exosomes shows promise for skin issues, but more research is needed.
108 citations
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August 2017 in “Clinical, Cosmetic and Investigational Dermatology” Microneedling is promising for treating various skin issues but needs more research to confirm its effectiveness and safety.
13 citations
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September 2020 in “Dermatologic Therapy” Microneedling may help hair loss, but needs more research.
Using microneedling with PRP improves skin and hair conditions more than microneedling alone.
140 citations
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December 2017 in “Journal of Controlled Release” Microneedles improve drug delivery in various body parts, are safe and painless, and show promise in cosmetology, vaccination, insulin delivery, and other medical applications.
January 2022 in “Surgical and Cosmetic Dermatology” Microneedling showed slight improvement in hair loss but no major changes in hair follicles or scalp condition.
17 citations
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May 2023 in “Pharmaceutics” Microneedles can precisely deliver cancer treatments with fewer side effects.
September 2024 in “Journal of the American Academy of Dermatology” Microneedling mildly regrows hair in androgenetic alopecia but not in other types.
86 citations
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August 2021 in “Polymers” Microneedles are effective for drug delivery, vaccinations, fluid extraction, and treating hair loss, with advancements in manufacturing like 3D printing.
5 citations
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January 2023 in “Journal of Cosmetic Dermatology” Intradermal microbotox injections work better and last longer for reducing large facial pores than topical application.
1 citations
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September 2018 in “Fisioterapia Brasil” Microneedling can effectively improve hair growth and thickness in men with hair loss.
1 citations
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July 2020 in “Revista Cereus” Using growth factors with microneedling is effective for treating hair loss.
PRP and microneedling are generally safe but can cause rare severe complications.
19 citations
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July 2019 in “Biomedical Microdevices” Microneedles can cause side effects like infection and allergic reactions, and precautions like test spots and sunscreen are recommended.
May 2016 in “Hair transplant forum international” 5 citations
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January 2016 in “Surgical and Cosmetic Dermatology” April 2026 in “Journal of Cosmetic Dermatology” January 2026 in “Journal of Cosmetic Dermatology” Microneedling can weaken hair in some AGA patients.
1 citations
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April 2021 in “International Journal Of Medical Science And Clinical Invention” Microneedling with growth factors improves facial rejuvenation more than microneedling with saline.
January 2023 in “Nanomedicine & nanotechnology open access” Microneedling is a promising, simple, and cost-effective treatment for hair loss that works well with other therapies.
February 2024 in “Skin Research and Technology” Microneedle therapy combined with serum effectively increases hair count in people with hair loss, with no side effects.
58 citations
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December 2017 in “Journal of The European Academy of Dermatology and Venereology” Microneedling can help stimulate hair growth, especially when used with other treatments, but it's not better than existing therapies.
June 2026 in “Drug Delivery and Translational Research” The study presents a solid microneedle booster (SMB) as an advanced microneedling platform for treating androgenetic alopecia (AGA). The SMB integrates spring-driven perpendicular stamping with simultaneous liquid dosing, improving microchannel reproducibility and early transport. Tests on porcine skin revealed that SMB achieved greater microchannel surface coverage and deeper penetration than a roller. It also enhanced early-phase permeation, accelerating hair regrowth when combined with minoxidil (MXD) in vivo. Histological analysis showed increased follicle enrichment in the SMB + MXD group. SMB provides a one-step, directionality-controlled microneedling method that enhances early transport and promotes follicular maturation, with potential for broader dermatologic applications.