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GlossarySuperoxide Dismutase

enzyme that neutralizes harmful superoxide radicals in cells

Superoxide Dismutase (SOD) is an enzyme that plays a crucial role in protecting cells from damage caused by superoxide radicals, which are harmful byproducts of cellular metabolism. By converting these superoxide radicals into less harmful molecules like hydrogen peroxide and oxygen, SOD helps to mitigate oxidative stress, which is linked to various diseases and aging processes.

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Efficient Intradermal Delivery of Superoxide Dismutase Using a Combination of Liposomes and Iontophoresis for Protection Against UV-Induced Skin Damage

research Efficient Intradermal Delivery of Superoxide Dismutase Using a Combination of Liposomes and Iontophoresis for Protection against UV-Induced Skin Damage

21 citations , January 2012 in “Biological and Pharmaceutical Bulletin”

Liposomes and iontophoresis effectively deliver protective enzymes into the skin against UV damage.

Preferential Recognition of Hydroxyl Radical-Modified Superoxide Dismutase by Circulating Autoantibodies in Patients with Alopecia Areata

research Preferential Recognition of Hydroxyl Radical-Modified Superoxide Dismutase by Circulating Autoantibodies in Patients with Alopecia Areata

12 citations , January 2014 in “Annals of Dermatology”

Modified superoxide dismutase may trigger an autoimmune response in alopecia areata.

Multifaceted Roles of Superoxide Dismutases (SODs) in Cellular Homeostasis and Cancer Progression: Redox Regulation and Therapeutic Implications

research Multifaceted roles of superoxide dismutases (SODs) in cellular homeostasis and cancer progression: Redox regulation and therapeutic implications

January 2025 in “Journal of Medical Biochemistry”

Superoxide dismutases help balance cell stress and may aid cancer treatment.

research Protective Effect of Superoxide Dismutase Against Hair Graying in a Mouse Model¶

33 citations , January 2004 in “Photochemistry and Photobiology”

Superoxide dismutase (SOD) can prevent hair graying in mice.

research Protective Effect of Superoxide Dismutase Against Hair Graying in a Mouse Model^¶

12 citations , November 2004 in “Photochemistry and Photobiology”

Superoxide dismutase (SOD) can prevent hair graying in mice.

research Machine Learning Guided Discovery of Superoxide Dismutase Nanozymes for Androgenetic Alopecia

3 citations , October 2022 in “Nano Letters”

Machine learning identified promising nanozymes for treating hair loss.

research SUPEROXIDE DISMUTASE LOADED NIOSOMES DELIVERY TO HAIR FOLLICLES: PERMEATION THROUGH SYNTHETIC MEMBRANE AND GUINEA PIG SKIN

2 citations , August 2019 in “International Journal of Applied Pharmaceutics”

Niosomes can effectively deliver Superoxide Dismutase to hair follicles, potentially helping prevent hair loss.

Evaluation of Antioxidant and Oxidant Status, Including Levels of Malondialdehyde and Superoxide Dismutase, in the Indian Population with Alopecia Areata

research Evaluation of antioxidant and oxidant status, including levels of Malondialdehyde (MDA) and Superoxide Dismutase (SOD), in the Indian population with alopecia areata

August 2022 in “International Journal of Health Sciences (IJHS) (En línea)”

Oxidative stress is important in causing alopecia areata.

research Differences of Superoxide Dismutase (SOD) Enzyme Levels Based on the Severity of Androgenetic Alopecia in Men

January 2020 in “International journal of scientific and research publications”

Lower SOD enzyme levels are linked to more severe hair loss in men.

research Assessment of Zinc and Copper Contents in Scalp Hair and Serum and Superoxide Dismutase, Glutathione Peroxidase and Malondialdehyde in Serum of Androgenetic Alopecia and Alopecia Areata Patients

4 citations , October 2011 in “Medical journal of Tabriz University of Medical Sciences and Health Services”

research Topical application of synthetic melanin promotes tissue repair

19 citations , November 2023 in “npj Regenerative Medicine”

Synthetic melanin applied to skin speeds up wound healing.

research Improvement of Antioxidant Defences in Keratinocytes Grown in Physioxia: Comparison of 2D and 3D Models

9 citations , June 2023 in “Oxidative Medicine and Cellular Longevity”

Physioxia improves keratinocyte protection against oxidative stress and better mimics real skin conditions.

research Antioxidants in dermatology

86 citations , June 2017 in “Anais Brasileiros de Dermatologia”

Antioxidants can benefit skin health but should be used carefully to avoid negative effects.

research Role of Oxidative Stress in Polycystic Ovary Syndrome

65 citations , May 2010 in “Current Women's Health Reviews”

Oxidative stress is a key factor in the development of Polycystic Ovary Syndrome, and weight management can improve symptoms.

Melatonin Promotes Secondary Hair Follicle Development in Early Postnatal Cashmere Goats and Improves Cashmere Quantity and Quality by Enhancing Antioxidant Capacity and Suppressing Apoptosis

research Melatonin promotes secondary hair follicle development of early postnatal cashmere goat and improves cashmere quantity and quality by enhancing antioxidant capacity and suppressing apoptosis

46 citations , March 2019 in “Journal of Pineal Research”

Melatonin improves cashmere goat hair growth and quality by increasing antioxidants and reducing cell death.

research Is Xanthine oxidase activity in polycystic ovary syndrome associated with inflammatory and cardiovascular risk factors?

26 citations , June 2016 in “Journal of Reproductive Immunology”

Women with PCOS have higher xanthine oxidase activity linked to inflammation and heart disease risks.

research Patients with vitiligo present fewer cardiovascular risk factors: results from a case–control study

17 citations , December 2011 in “Journal of the European Academy of Dermatology and Venereology”

People with vitiligo may have a lower risk of heart disease.

research In Vitro and In Vivo Anti-Aging Effect of Coffee Berry Nanoliposomes

13 citations , September 2023 in “Molecules”

Liposomal coffee berry extract improves skin elasticity and reduces melanin better than regular extract.

research Oxidative stress in androgenetic alopecia.

13 citations , March 2017 in “PubMed”

People with a common type of hair loss have higher stress levels in their body, and treatments that reduce this stress could help.

research Alterations in transcriptome and antioxidant activity of naturally aged mice exposed to selenium-rich rice

10 citations , April 2019 in “Environmental Science and Pollution Research”

Eating selenium-rich rice improved antioxidant activity and signs of aging in mice.

research Transplanted hair follicle mesenchymal stem cells alleviated small intestinal ischemia–reperfusion injury via intrinsic and paracrine mechanisms in a rat model

6 citations , October 2022 in “Frontiers in Cell and Developmental Biology”

Transplanted hair follicle stem cells can heal damaged rat intestines.

research Lactobacillus paracasei HY7015 and Lycopus lucidus Turcz. Extract Promotes Human Dermal Papilla Cell Cytoprotective Effect and Hair Regrowth Rate in C57BL/6 Mice

3 citations , November 2022 in “Molecules/Molecules online/Molecules annual”

The substances improved hair regrowth and protected hair cells in humans and mice.

Single Dose Gamma Irradiation Induced Angiogenesis in Rat Skin Hair Follicles

research Effects of supplementation with two probiotic strains (Lactobacillus helveticus and Bifidobacterium longum) on hormonal status, oxidative stress, and clinical symptoms in women with polycystic ovary syndrome: a randomized clinical trial

2 citations , November 2025 in “Nutrition Journal”

Probiotic supplements may help reduce inflammation and oxidative stress in women with PCOS.

research Evaluation of Resistance Resources and Analysis of Resistance Mechanisms of Maize to Stalk Rot Caused by Fusarium graminearum

2 citations , July 2023 in “Plant Disease”

Some maize lines resist stalk rot better due to specific genes and enzyme activities.

research Zinc‐Coordinated Trienzyme Nanogel Cascade Therapy for Accelerated Post‐Pancreatectomy Cutaneous Wound Healing

1 citations , July 2025 in “Advanced Materials”

The zinc-coordinated nanogel therapy speeds up wound healing after pancreas surgery by balancing metabolism and fighting bacteria.

research Зміни показників оксидативного стресу при місцевому застосуванні міноксидилу в щурів з хімічною депіляцією

1 citations , September 2023 in “Pharmacology and Drug Toxicology”

Minoxidil reduces oxidative stress and helps hair regrowth.