88 citations
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August 2019 in “Frontiers in immunology” Tyrosine kinases are important in skin autoimmune diseases and could be targets for new treatments.
24 citations
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September 2014 in “PloS one” Thyroid hormone receptors are essential for hair growth and wound healing.
22 citations
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May 2007 in “Molecular Biotechnology” 28 citations
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September 2011 in “Stem Cell Reviews and Reports” 20 citations
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November 2014 in “Developmental Dynamics” Palate formation and skin healing share similar biological processes.
15 citations
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July 2024 in “Current Issues in Molecular Biology” Understanding molecular processes in skin development is key to creating targeted treatments for skin disorders.
822 citations
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January 2021 in “Genome biology” scMC effectively separates biological signals from technical noise in single-cell genomics data.
488 citations
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July 2021 in “Cell” Fibroblasts are crucial for tissue repair and inflammation, and understanding them can help treat fibrotic diseases.
479 citations
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June 2014 in “Science” Epithelial stem cells can adapt and help in tissue repair and regeneration.
426 citations
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August 2014 in “Nature Medicine” Skin stem cells interacting with their environment is crucial for maintaining and regenerating skin and hair, and understanding this can help develop new treatments for skin and hair disorders.
375 citations
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June 2013 in “Biochimica et biophysica acta. Molecular cell research” Cornification is how skin cells die to form the protective outer layer of skin, hair, and nails.
318 citations
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January 2022 in “Signal Transduction and Targeted Therapy” The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.
214 citations
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April 2017 in “Cell” Different small areas within hair follicles send specific signals that control what type of cells stem cells become.
189 citations
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July 2009 in “The Journal of clinical investigation/The journal of clinical investigation” Epidermolysis bullosa simplex causes easily blistered skin due to faulty skin cell proteins, leading to new treatment ideas.
143 citations
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May 2017 in “Nature cell biology” Wounded skin cells can revert to stem cells and help heal.
129 citations
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July 2019 in “Stem Cell Research & Therapy” Epidermal stem cells help heal severe skin wounds and have potential for medical treatments.
124 citations
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July 2017 in “eLife” Type XVII collagen helps control skin cell growth and could be a target for anti-aging treatments.
122 citations
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December 2022 in “International Journal of Molecular Sciences” Nanoparticles improve skin treatment but need more research on safety and effectiveness.
105 citations
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October 2017 in “Stem cells” Wnt signaling is crucial for skin development and hair growth.
101 citations
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December 2014 in “Stem Cells and Cloning Advances and Applications” Oral stem cells show promise for tissue repair, but more human trials are needed.
98 citations
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December 2015 in “The Journal of Cell Biology” Keratin is crucial for skin barrier formation and affects mitochondrial function.
91 citations
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December 2000 in “The journal of cell biology/The Journal of cell biology” Scientists successfully created mouse hair proteins in the lab, which are stable and similar to natural hair.
89 citations
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June 2012 in “Anais Brasileiros de Dermatologia” Actinic keratosis can lead to skin cancer, is more common in fair-skinned people, and can be reduced with sunscreen and treated effectively.
87 citations
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July 2009 in “Journal of Cell Science” Deleting the CDSN gene causes severe skin and hair problems, leading to death.
86 citations
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November 2020 in “Annals of Oncology” Early intervention and tailored management can reduce skin side effects from cancer treatments.
86 citations
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February 2012 in “Journal of Clinical Investigation” Stem cells in hair follicles are diverse and change throughout the hair cycle.
86 citations
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April 2009 in “Journal of anatomy” Hard skin features like scales, feathers, and hair evolved through specific protein changes in different animal groups.
84 citations
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April 2002 in “Archives of Dermatology” Loose anagen hair syndrome may be caused by keratin gene mutations.
72 citations
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November 2017 in “Journal of developmental biology” The Hedgehog signaling pathway is important for skin and hair growth and can lead to cancer if it doesn't work right.
72 citations
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November 2002 in “Journal of Investigative Dermatology” Estrogen receptor α controls hair growth cycles and skin thickness in male mice.