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As skin cells mature, vitamin D receptor levels decrease while retinoid X receptor α levels increase.

Lack of Ctip2 in skin cells delays wound healing and disrupts hair follicle stem cell markers in mice.

A specific gene region can control targeted and responsive gene expression in mice, useful for skin disorder treatments.

Mouse and human keratin 16 can both form filaments, with differences likely due to the tail domain, not the helical domain.

Acne treatment with isotretinoin increases the presence of p53, a protein, in skin and oil glands, which may help reduce acne severity.

Activating cannabinoid receptor 1 reduces certain keratin levels, potentially aiding psoriasis treatment.

A 4kb fragment of the desmocollin 3 promoter targets gene expression to specific skin and hair follicle areas.

HoxC genes are crucial for normal hair and nail development.

Mettl3 is essential for normal tissue development and self-renewal by regulating gene expression.

The article concludes that creating a detailed map of normal human skin at the single-cell level is important.

Overexpressing the MSX-2 gene in mice causes skin and hair growth issues.

Stem cells in hair follicles can become various cell types, including neurons.

Corneal cells can transform into hair-producing skin cells when exposed to certain signals.

There are two types of stem cells in rodent hair follicles, each with different keratin proteins.

Fatty acid composition in human skin, mouth, and hair cells varies with keratinization, and cultured cells show essential fatty acid deficiency.

A3 antibody helps identify key cells in rat hair follicle development.

ASH2L is essential for skin and hair development.

Myc activation reduces skin stem cells by affecting cell adhesion.

Keratin expression reflects cell organization and differentiation, not causes it.

We now understand more about what causes acne and this could lead to better, more personalized treatments.

Corneal cells can transform into skin and hair cells through specific signals.

COL17A1 is crucial for preventing hair graying and loss by supporting hair and pigment stem cells.

Human hair keratins were cataloged, showing their roles in hair differentiation stages.

p63 controls Satb1 to help skin develop properly.

Fgfr2b helps maintain healthy skin and prevent cancer.

Rats can't grow new hair follicles after skin wounds, unlike mice, due to differences in gene expression and response to WNT signaling.

Hormones and stretching both needed for nipple area skin growth in mice.

Understanding keratinization is crucial for treating skin conditions like ichthyoses and psoriasis.

Mechanical force is important for the first contact between skin cells and hair growth in mini-organs.

Protein profiling of forehead skin can help distinguish between frontal fibrosing alopecia and androgenetic alopecia.