120 citations
,
July 2005 in “Dermatologic surgery” Niacinamide improves aging skin and is safe for use in cosmetics.
118 citations
,
May 2015 in “European journal of pharmaceutics and biopharmaceutics” The hydrogel with a 1:3 ratio of hydroxyethyl cellulose to hyaluronic acid is effective for delivering drugs through the skin to treat acne.
114 citations
,
February 2012 in “International Journal of Dermatology” Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.
113 citations
,
December 2000 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” KGF and activin are crucial for skin healing and repair.
106 citations
,
October 2016 in “Cell Stem Cell” PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.
93 citations
,
January 2016 in “British Journal of Dermatology” Eating a high-glycemic diet may worsen acne by increasing certain protein levels and expressions in the skin.
84 citations
,
January 2018 in “Biomaterials Science” Sericin hydrogels heal skin wounds well, regrowing hair and glands with less scarring.
82 citations
,
March 2012 in “Development” Drosha and Dicer are essential for hair follicle health and preventing DNA damage in skin cells.
78 citations
,
September 2008 in “International Journal of Cosmetic Science” The document concludes that various clinical methods are used to assess ageing skin and the effectiveness of anti-ageing products.
77 citations
,
March 2014 in “Cold Spring Harbor Perspectives in Medicine” Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.
76 citations
,
May 2007 in “Menopause International” After menopause, women lose a lot of skin collagen, but estrogen replacement might improve skin health.
74 citations
,
June 2018 in “Cell death and disease” Restoring mitochondrial function in mice reversed their skin wrinkling and hair loss.
70 citations
,
May 2014 in “JAMA Dermatology” The representation of skin conditions in medical reviews partly matches their real-world impact.
57 citations
,
April 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” Vitamin D receptor is crucial for starting hair growth after birth.
56 citations
,
March 2016 in “International Wound Journal” Skin grafts are effective for chronic leg ulcers, especially autologous split-thickness grafts for venous ulcers, but more data is needed for diabetic ulcers.
55 citations
,
September 2017 in “Journal of Cosmetic Dermatology” Platelet-rich plasma, taken from a person's own blood, can help rejuvenate skin, stimulate hair growth, and treat hair loss, but more research is needed to confirm its safety and effectiveness.
53 citations
,
April 2021 in “Cell Host & Microbe” Skin bacteria, specifically Staphylococcus aureus, help in wound healing and hair growth by using IL-1β signaling. Using antibiotics on skin wounds can slow down this natural healing process.
50 citations
,
December 2020 in “Bioactive Materials” Wound dressing absorbs fluid, regenerates hair follicles, and heals skin burns.
49 citations
,
March 2019 in “Journal of Investigative Dermatology” Skin fat plays a key role in immune defense and healing beyond just storing energy.
48 citations
,
August 2018 in “Nature Communications” JunB is crucial for maintaining healthy skin and hair follicles.
48 citations
,
April 2010 in “Journal of the European Academy of Dermatology and Venereology” Men are more likely to get infectious skin diseases, while women are more prone to autoimmune and pigment-related skin conditions, influenced by biological and environmental factors.
48 citations
,
January 2000 in “Hormone Research in Paediatrics” Cytokines and neuropeptides are key in controlling androgen levels, affecting skin and hair conditions.
44 citations
,
September 2019 in “The EMBO Journal” Lymphatic vessels are essential for hair follicle growth and skin regeneration.
44 citations
,
October 2011 in “Gynecological Endocrinology” Menopause significantly reduces skin collagen, leading to thinner, less elastic skin, and hormone replacement may help but requires careful consideration.
44 citations
,
July 2011 in “Dermato-endocrinology” Thyroid hormone affects skin health, with too little causing rough, pale skin and too much leading to smooth, thin skin, and may also impact wound healing and skin conditions.
40 citations
,
November 2009 in “Experimental Dermatology” The mineralocorticoid receptor may play a role in skin and hair health and could be a new target for treating related disorders.
39 citations
,
August 2022 in “Cell Death and Disease” DA-MeHA hydrogel effectively aids stem cell-based skin regeneration.
38 citations
,
September 2014 in “Cell and Tissue Research” The hair follicle infundibulum plays a key role in skin health and disease, and understanding it better could lead to new skin disease treatments.
37 citations
,
January 2019 in “Food science & nutrition” Bergamot may improve heart health, skin conditions, and mood, but more research is needed to confirm these benefits.
36 citations
,
September 2009 in “Journal of Cellular and Molecular Medicine” New treatments targeting skin stem cells show promise for skin repair, anti-aging, and cancer therapy.