13 citations
,
January 2017 in “Chemical & Pharmaceutical Bulletin” Certain compounds, especially those with a propionic substituent, could potentially be new treatments for hair loss and similar disorders.
12 citations
,
February 2010 in “Tetrahedron Letters” New minoxidil compounds with better water solubility were made, but their full effects and safety need more research.
12 citations
,
April 1995 in “Journal of Medicinal Chemistry” The new compounds moderately block a specific enzyme and strongly counteract a male hormone, suggesting potential for treating certain male-related health conditions.
11 citations
,
June 2016 in “European Journal of Medicinal Chemistry” Compounds 6f and 6g effectively stop prostate cancer cell growth without harming healthy cells.
10 citations
,
January 2010 in “International Journal of Trichology” Synthetic hair fibers for hair restoration were controversial in 2009 due to health risks and lack of support from the International Society of Hair Restoration.
9 citations
,
March 2022 in “Antioxidants” Synthetic antioxidants are effective, cheap, and stable, with some like zinc and cholecalciferol reducing child and cancer deaths, but the safety of additives like BHA, BHT, TBHQ, and PEG needs more research.
8 citations
,
June 1979 in “JAMA” Synthetic hair implants can cause severe infections and are risky.
8 citations
,
January 2013 in “Medicinal chemistry” The compound 4c showed strong potential as an anticancer agent.
7 citations
,
June 1989 in “Steroids” Researchers successfully made new compounds for hormone level tests, but one attempt led to an unexpected product, correcting a past error.
6 citations
,
January 1989 Synthetic hair implants can be used to cover small bald spots.
6 citations
,
January 2016 in “Bioorganic & Medicinal Chemistry Letters” Some minoxidil combinations can help differentiate leukemia cells without harming other cells.
6 citations
,
November 2004 in “Bioorganic & Medicinal Chemistry Letters” Scientists created iodinated arylhydantoins and arylthiohydantoins that could potentially be used for imaging prostate cancer. Some versions with specific side-chains showed high potential for this use.
5 citations
,
April 2013 in “Journal of Cosmetic and Laser Therapy” Argireline significantly reduces wrinkles.
5 citations
,
February 2012 in “Aesthetic Plastic Surgery” A man developed skin cancer on his scalp after multiple artificial hair grafts.
5 citations
,
January 2006 in “Indian Journal of Dermatology, Venereology and Leprology” Synthetic hairs are not recommended for use.
5 citations
,
March 2000 in “PubMed” The study found that using polyamide synthetic hair for implants is generally safe and gives good results with proper medical follow-up.
5 citations
,
November 2015 in “Journal of Enzyme Inhibition and Medicinal Chemistry” Certain derivatives are more effective 5α-reductase type 2 inhibitors than finasteride.
4 citations
,
February 2020 in “Journal of Cosmetic Dermatology” Synthetic hair implants can cause severe scalp problems and removing them improves conditions; natural hair transplants are safer and more effective.
4 citations
,
December 2010 in “Copernican Letters” Synthetic polypeptides in cosmetics may help with anti-aging, but their effectiveness on real skin is uncertain.
4 citations
,
January 2011 Phenylpropanoid sucrose esters show potential as anticancer agents.
3 citations
,
January 2017 in “PubMed” A man got a scalp infection from synthetic hair implants because the procedure wasn't done by a doctor and was poorly managed.
2 citations
,
January 2022 in “Skin Pharmacology and Physiology” Dexamethasone increases the activity of androgen receptors in human skin cells, which may link it to certain types of hair loss.
2 citations
,
August 2012 in “Aesthetic Plastic Surgery” The letter argues that blaming synthetic hair implants for scalp cancer based on one report is biased and possibly coincidental.
2 citations
,
January 2011 in “Andrologia” Flutamide and a new synthetic steroid affected brain and prostate chemicals and showed potential for treating androgen-related conditions and epilepsy.
1 citations
,
March 2012 in “Journal of Dermatological Science” Testosterone, progesterone, and levonorgestrel change enzyme levels related to fat production in hamster skin, which could affect skin oil and acne.
December 2025 in “Current Issues in Molecular Biology” New steroid compounds may help with hormonal therapy and have potential benefits for glucose disorders, but more research is needed.
November 2025 in “Applied Research” Synthetic curcumin derivatives improve treatment for diabetes and cancer.
October 2025 in “International Journal of Research and Review” Herbal shampoo bars are eco-friendly and beneficial for hair and scalp but need improvements for wider use.
Bioactive compounds in neurocosmetics can improve skin health and emotional well-being.
December 2024 in “Asian Journal of Pharmaceutical and Clinical Research” Combining synthetic and herbal treatments may help with hair loss, but more research is needed.