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research Minoxidil and Tail-like Effect
Minoxidil caused hair to grow in unintended areas, like a tail, in a young girl.
research Phytochemicals for Hair Health Targeting Growth Signaling Molecules in Hair Follicular Stem Cells: A New Strategy for Hair Growth
Natural extracts may promote hair growth with fewer side effects than conventional treatments.
research Vitamin D receptor cross-talk with p63 signaling promotes epidermal cell fate
Vitamin D helps skin stem cells heal wounds by working with a key skin protein.
research 3D organotypic skin models recapitulate autoantibody-driven pemphigus pathomechanisms and targeted therapeutic response
The 3D skin model mimics pemphigus vulgaris and helps test treatments.
research Natural Compounds Targeting MAPK, PI3K/Akt, and JAK/STAT Signaling in Papillary Thyroid Cancer
Natural compounds may help treat advanced papillary thyroid cancer by targeting specific molecular pathways.
research Performance exploration of multi-gene panels of alopecia areata susceptibility and drug-binding targets
Methotrexate, resveratrol, and curcumin may help treat alopecia areata by targeting immune cells.
research Skin development in the gray short‐tailed opossum (Monodelphis domestica)—From skin respiration to thermoregulation
Gray short-tailed opossums' skin shifts from helping with breathing to regulating body temperature as they grow.
research MicroRNA-181a Targets GNAI2 and Affects the Proliferation and Induction Ability of Dermal Papilla Cells: The Potential Involvement of the Wnt/β-Catenin Signaling Pathway
MicroRNA-181a slows sheep hair growth by targeting GNAI2 and affecting a key growth pathway.
research Hairy drinking may cause severe hangover symptoms in patients taking low‐dose minoxidil
Avoid alcohol when taking low-dose minoxidil to prevent severe hangovers.
research NF-κB in biology and targeted therapy: new insights and translational implications
NF-κB signaling is crucial in many diseases and can be targeted for new treatments.
research Innovative Therapeutic Strategies in TYK2-Targeted Treatments: From Cancer to Autoimmune Disorders
TYK2 inhibitors show promise for treating cancer and autoimmune disorders.
research Fascia Layer—A Novel Target for the Application of Biomaterials in Skin Wound Healing
The fascial layer is a promising new target for wound healing treatments using biomaterials.
research First Report of ‘Candidatus Phytoplasma aurantifolia’ Associated with the Invasive Weed Eclipta prostrata in Taiwan
'Eclipta prostrata' plants in Taiwan are infected with 'Candidatus Phytoplasma aurantifolia'.
research Bakteriyel Selüloz Tabanlı Hidrojel Taşıyıcı ile Topikal Uygulanan Tideglusib’in Sıçanlarda Oluşturulan Palatinal Yaranın İyileşmesi Üzerine Etkisinin Makroskobik Değerlendirmesi: Bir Öncül Çalışma
Tideglusib with a bacterial cellulose hydrogel improves wound healing in rats.
research miR-27a Targeting PIK3R3 Regulates the Proliferation and Apoptosis of Sheep Hair Follicle Stem Cells
Blocking miR-27a increases sheep hair follicle stem cell growth and decreases cell death, which could help improve wool quality and treat hair loss.
research Computational Screening of Repurposed Drugs Targeting Sars-Cov-2 Main Protease By Molecular Docking
Danoprevir, remdesivir, and saridegib may effectively inhibit SARS-CoV-2.
research Phyllanthus emblica Extract-loaded Transfersomes for Hair Follicle Targeting: Phytoconstituents, Characterization, and Hair Growth Promotion
Phyllanthus emblica extract in transfersomes is a promising treatment for hair growth.
research Pituitary Dependent Hyperadrenocorticism in a Golden Lion Tamarin (Leontopithecus rosalia)
A golden lion tamarin had Cushing's disease due to a pituitary tumor, leading to its euthanasia.
research Numbing Aesthetics: Taste and Tempers of Peppercorn / Mountain Pepper / Sanshō
Peppercorn's rich cultural and historical significance was reduced to just a flavor by 20th-century chemists.
research 312 CRISPR/Cas9-based targeted genome editing for correction of recessive dystrophic epidermolysis bullosa using iPS cells
The research showed that CRISPR/Cas9 can fix mutations causing a skin disease in stem cells, which then improved skin grafts in mice, but more work on safety and efficiency is needed.
research Hair loss or taste loss?
research Case 5: A Very Tall 7-year-old Boy with Medulloblastoma
A 7-year-old boy with a brain tumor developed early puberty, which was successfully treated with medication.
research Formulation and Evaluation of Minoxidil Gel Using Acrylamide/Sodium Acryloyldimethyl taurate copolymer for Alopecia areata
The minoxidil gel is stable and effective for treating alopecia areata.
research Androgenic Alopecia: Cross-Talk Between Cell Signal Transduction Pathways
Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.
research Sensitization and Clinically Relevant Allergy to Hair Dyes and Clothes from Black Henna Tattoos: Do People Know the Risk? An Uncommon Serious Case and a Review of the Literature
Black henna tattoos can cause severe allergies to hair and textile dyes, and there's a need for greater public awareness and regulation.
research Finasteride Quantification in Human Plasma by High-Performance Liquid Chromatography Coupled to Electrospray Ionization Tandem Mass Spectrometry. Application to a Comparative Pharmacokinetics Study
New method measures finasteride in plasma, finds two formulations bioequivalent.
research Ultra-Performance Liquid Chromatography with Electrospray Ionization Tandem Mass Spectrometry for the Determination of Ketoconazole in Anti-Dandruff Shampoo
The method accurately measures the amount of ketoconazole in anti-dandruff shampoo and cream, and can also be used to monitor the drug in human plasma.
research FORMULATION AND EVALUATION OF CONTROLLED RELEASE MATRIX TABLETS OF FINASTERIDE
The F9 formulation of Finasteride tablets, using Eudragit, successfully controlled drug release.
research Screening and confirmation methods of the major urinary metabolite of finasteride–carboxy-finasteride by liquid chromatography–mass spectrometry and liquid chromatography–tandem mass spectrometry
New methods can detect finasteride's major urinary metabolite in urine for up to 49 hours.