![The Synthesis of (−)-4-Methyl-8-Chloro-Trans-1,2,3,4,4a,5,6,10b-Octahydrobenzo-[f]-Quinolin-3-One-[3-14C] (LY300502-14C) via a Circuitous Route](/images/research/73bab8dc-bdf0-45e3-8ef7-73d0d4b93cb1/small/21074.jpg)
research The synthesis of (−)-4-methyl-8-chloro-trans-1,2,3,4,4a,5,6,10b-octahydrobenzo-[f]-quinolin-3-one-[3-14C] (LY300502-14C]) via a circuitous route
Scientists made a carbon-14 labeled version of a drug with a 48% yield and over 99% purity.
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870-900 / 1000+ results research Disease-related biomarkers as experimental endpoints in 3D skin culture models
research Keratin-modified waterborne polyurethane: an alternative circular economy technology for adding value to cattle hair waste from leather tanneries
research Development of Uniform Protocol for Alopecia Areata Clinical Trials
A standard protocol for alopecia areata clinical trials was created to improve consistency and encourage more research.
research The Hair Cell Analysis Toolbox: A machine learning-based whole cochlea analysis pipeline
The Hair Cell Analysis Toolbox automates and improves the analysis of cochlear hair cells using machine learning.
research LB1027 Identifying the mechanism of tension-associated tissue fibrosis based on single cell RNA sequencing on keloid scar
Mechanical tension worsens keloid scars by activating inflammation and fibrosis pathways.
research Professional skills : a pilot study and report on cross professional competencies
Long non-coding RNA Xist plays a key role in sex bias in lupus and rheumatoid arthritis, especially in females.
research Discipline-based staff development courses to promote a sustainable SOTL environment : An example from science and engineering at Uppsala University
Breast cancer patients need better psychological support to improve their quality of life.
research Case Study on Treating Scarring alopecia and Alopecia arreata Using Low Level Laser Therapy and Acupuncture
Low level laser therapy and acupuncture significantly improved hair growth in a patient with alopecia.
research Effect of diode pumping solid state laser with wavelength 589 nm on gene expression of interlukine-2 and interferon-gamma Lowercase in human T-lymphocytes
A 589 nm laser increases IL-2 and IFN-y gene expression in human T-cells.
research CD44/TRPV1 dual-targeted nanocarrier enables drug retention and multidimensional therapy for inflammatory skin diseases
research Abstracts
Ablative fractional laser treatment nearly matches the gene reduction effects of topical vismodegib in skin cancer.
research Synergistic Wound Healing: Unraveling the Multi-Target Effects of Traditional Chinese Medicine and Its Biomaterials on Chronic Wound Pathways
Traditional Chinese Medicine and biomaterials help heal chronic wounds by targeting multiple pathways.
research IoT Based Lavender Plant Monitoring System
The system helps lavender plants grow better by monitoring and adjusting their environment.
research C36 LONG TERM TREATMENT WITH FINASTERIDE IN MEN WITH LUTS - A 13 YEARS FOLLOW UP
research Comprehensive Program Planning for the Integration of 21st Century Learning Center After-School Programs with Regular Day Programs and Community Partners.
The report expanded knowledge of MBTPS1-related disorders by identifying new symptoms.
research Pharmacophore Modeling and Three Dimensional Database Searching for Drug Design Using Catalyst: Recent Advances
The document concludes that Catalyst software is effective for drug design, identifying potent compounds for various medical conditions.
research Proceedings of the III International Scientific and Practical Conference
The conference emphasized innovative solutions for global challenges, including disaster architecture, education, health, and economic impacts.
research Transgenic Flash Mice for In Vivo Quantitative Monitoring of Canonical Wnt Signaling to Track Hair Follicle Cycle Dynamics
Researchers developed a mouse model that tracks hair growth using bioluminescence, improving accuracy in studying hair cycles.
research rwSALT: a regrowth-weighted SALT score providing direct pixel-level measurement rather than visual estimation
rwSALT accurately measures hair regrowth in alopecia areata using scalp photos.
research Translation into Spanish Language (México), Transcultural Adaptation, and Validation of the Quality of Life Questionnaire in Female Pattern Hair Loss (WAA-QoL-Sp)
The Spanish version of the WAA-QoL questionnaire is reliable and valid for assessing quality of life in women with hair loss.
research Evaluation of wavelength-dependent hair growth effects on low-level laser therapy: an experimental animal study
The 830-nm wavelength was most effective at promoting hair growth in rats using low-level laser therapy.
research Examining the Safety and Efficacy of Low-Level Laser Therapy for Male and Female Pattern Hair Loss: A Review of the Literature
Low-level laser therapy safely and effectively improves hair growth and coverage for male and female pattern hair loss.
research Comparison of allogeneic stem cell transplant conditioning regimens in AML, MDS and CLL
Busulfan/cyclophosphamide and total bone irradiation are equally effective for AML transplants.
research Studying Cytotoxic T-lymphocyte- Associated Antigen-4 (CTLA-4) gene Polymorphism in a Sample of Iraqi Women with Polycystic Ovarian Syndrome
The CTLA-4 gene change studied does not affect Polycystic Ovarian Syndrome in the women tested.
research AGA practitioner challenges: A mixed‐methods pilot survey
Practitioners treating hair loss need better education and resources to overcome challenges like commercial bias and ethical dilemmas.
research Hair Transplantation Outcomes in Patients with Poor Donor Site Density: Challenges and Innovative Solutions
Innovative techniques improve hair transplant results and satisfaction in patients with low donor hair density.
research Plum-Blossom Needle Tapping combined with Ginger Juice Rubbing as an effective therapy for preventing hair loss in female obese patients after metabolic bariatric surgery: A 6-month 2×2 factorial design research protocol v1
Plum-blossom needle tapping with ginger juice rubbing may help prevent hair loss after bariatric surgery.
research 551 Combining Laser Capture Microdissection and RNAseq Analysis to Generate a Human Anagen Hair Follicle Transcriptome Atlas
Researchers made a detailed map of gene activity for different parts of human hair follicles to help create targeted hair disorder treatments.
research 465 Multicenter prospective study on the efficacy of narrowband ultraviolet B treatment and its effect on quality of life, anxiety, depression in plaque psoriasis patients
Narrowband Ultraviolet B treatment can significantly reduce anxiety in psoriasis patients, but it doesn't significantly affect depression.