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Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

The research found that androgens help control blood flow in the rat prostate through a specific binding site.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

Trastuzumab deruxtecan is effective for advanced breast cancer but has side effects like nausea and fatigue.

Behavioral interventions, especially habit reversal training, are most effective for treating trichotillomania in children.

Delta opioid receptors help regulate touch sensation by reducing neurotransmitter release in the spinal cord.

Torilin from Torilis japonica can inhibit testosterone 5α-reductase but is less effective than finasteride.

The research gives new understanding on how human steroid 5α-reductases work and how drugs like finasteride inhibit them, which could help in creating new drugs.

5α-reductases increase epitestosterone's effect on androgen receptors.

High-throughput LC-MS screening is effective for finding new autotaxin inhibitors for asthma treatment.

Combining a GnRH agonist with a low-dose oral contraceptive is more effective and safer for treating hirsutism than using either alone.

Flutamide and a new synthetic steroid affected brain and prostate chemicals and showed potential for treating androgen-related conditions and epilepsy.

Blocking the androgen receptor in skin cells reduces their growth response to male hormones, suggesting a possible treatment for skin conditions linked to androgens.

TRH stimulates human hair growth and extends the hair growth phase.

Trazodone might help reverse post finasteride syndrome.

Some new progesterone derivatives are better at blocking testosterone conversion than a common drug.

Somatostatin analogues effectively manage ectopic ACTH syndrome when surgery isn't possible.

Researchers developed reliable models to predict how well certain compounds bind to androgen receptors, emphasizing the importance of atomic electronegativity.

Human hair follicles have a scent receptor that can influence hair growth.

New pyrazole-based inhibitors show promise for treating metabolic diseases and other conditions.

Method accurately measures finasteride and tamsulosin in combined drug form.

Botulinum neurotoxin A is effective and safe for treating various conditions, but more clinical trials are needed to fully assess its benefits and risks.

Topical sulfonylurea may reduce excessive hair growth caused by certain medications.

Tamsulosin and finasteride improve heart function and circadian rhythm in elderly men with heart failure and prostate issues.

AA–TF#15 significantly promotes hair regrowth and could be an effective treatment for androgenic alopecia.