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Hormone treatments in transsexual individuals reduce hair growth and oil production in male-to-females and increase them in female-to-males.

Two new mutations in the AR gene linked to severe androgen insensitivity were found.

A woman's rare ovarian tumor was treated with surgery, which stopped her symptoms and normalized her hormone levels.

5-alpha reductase deficiency leads to male sexual development issues and treatments like finasteride help with prostate enlargement and hair loss.

A rare gene variant causes sexual development issues in siblings, needing personalized treatment.

Androgens reduce THY1 in skin cells, leading to less fat, more fibrosis, and worse healing in males.

A multidisciplinary approach is crucial for safe and effective hormone treatment in gender-dysphoric individuals, with specific guidelines for adolescents and adults.

A 63-year-old woman's male-like symptoms were caused by a rare testosterone-producing ovarian tumor, treated by removing her ovaries and fallopian tubes.

High doses of testosterone disrupt hormone levels and receptor expression in the uterus, affecting fertility.

Gender-affirming hormone therapy in South Korea aligns with international guidelines and has specific side effects.

Low testosterone in men is a risk factor for a specific heart rhythm issue, and testosterone treatment may help prevent it.

The case showed the need for quick investigation of virilization in women and how emotional health is linked to physical health.

Hormonal treatment in transgender women reduces semen quality, but stopping treatment may improve it.

Most youth with gender dysphoria received hormones, had minor complications, and showed a decrease in suicide attempts after treatment.

Early medical support for transgender youth is important for their health, with low regret for gender-affirming hormone use and a need for knowledgeable care providers.

Sex hormones affect liver fat and metabolic health differently in men and women.

Testosterone protects female heart cells from stress by activating estrogen receptors.

Ovarian stromal hyperplasia can cause high testosterone in postmenopausal women and is treated by removing the ovaries.

An 8-year-old boy's early puberty was caused by a rare hormone-secreting brain tumor, which was successfully treated with surgery.

Men might have a version of the female disease, polycystic ovarian syndrome, shown by changes in hormone levels and early baldness, but more research is needed to fully understand it.

Hormonal therapy for transgender individuals carries health risks but is a personal choice.

Gonadal biopsy is the best method to diagnose gonadal dysgenesis.

The document concludes that transsexual individuals often experience improved quality of life after transitioning, despite higher risks of psychiatric issues and mortality.

Ovarian tumors should be considered when postmenopausal women show signs of virilization.

A new genetic mutation causes severe Leydig cell hypoplasia, affecting sexual development.

Masculinizing hormone therapy increases the risk of hair loss in transgender and gender-diverse patients.

Estrogens and androgens are crucial for male fertility.

5alpha-reductase 2 is crucial for proper male brain development and sexual differentiation.

Surgery improved symptoms and normalized hormone levels in a woman with an adrenal tumor.