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Gender-affirming hormone therapy improves physical performance in trans men to the level of cisgender men, while in trans women, it increases fat mass and decreases muscle mass, with no advantage in physical performance after 2 years.

Local testosterone treatment improved sexual desire in a female with fragile X syndrome.

Transgender men need personalized cancer care and continued testosterone therapy for well-being.

A 22-year-old woman with a rare genetic condition was successfully treated to develop normal female characteristics and regular menstruation.

Hyperthyroidism can hide signs of high androgen levels in females.

Testosterone pellets might work for transgender men's hormone therapy, but more research is needed.

A postmenopausal woman's hormone imbalance and symptoms improved after removing benign ovarian tumors.

Finasteride treatment changes Cx43 in rat testes, possibly causing fertility issues.

A toddler with a rare adrenal gland tumor causing male-like physical changes was successfully treated with surgery.

Hormone therapy in transgender individuals can increase acne and affect hair growth and loss.

Mosaic Klinefelter syndrome can affect male fertility and may be missed in routine tests.

Scientists restored fertility in male mice lacking a key fertility gene by using a modified gene.

Mutations in the androgen receptor gene cause androgen insensitivity, leading to female traits in genetically male individuals.

A woman with high testosterone and an adrenal nodule had an ovarian tumor causing her symptoms, which improved after the tumor was removed.

Testosterone increases hair growth and acne in transgender men.

Surgical removal of a rare ovarian tumor improved symptoms and hormone levels in a postmenopausal woman.

Hormonal therapy changes skin and hair in transgender patients, who need better researched dermatologic care.

Men with low testosterone or breast growth should be checked for Cushing syndrome.

Confirm testosterone levels with advanced tests to avoid unnecessary procedures.

Blood tests can detect ovarian Leydig cell tumors when scans don't, and surgery can confirm and treat these tumors.

Facial feminization surgery helps make facial features more feminine, improving patient satisfaction and safety.

Testosterone replacement therapy improves libido, mood, muscle strength, and bone density in men with Testosterone Deficiency Syndrome.

Leydig cells can cause testosterone-secreting adrenal tumors in women.

The document concludes that individualized Facial Feminization Surgery plans and comprehensive care are crucial for successful outcomes.

An 81-year-old woman's severe male hormone symptoms were caused by an ovarian tumor, which was treated with surgery.

Leydig cell tumors in the ovary can cause high testosterone and male traits in postmenopausal women but are treatable with surgery.

Clomiphene testing can help find ovarian causes of high testosterone in postmenopausal women.

Early physical exams are crucial for timely Klinefelter syndrome diagnosis.