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Australian doctors experienced in adult transgender healthcare mostly prescribe intramuscular testosterone and oral estradiol, recommend mental health assessments before hormone therapy, and support improved training and guidelines.

Prepubertal girls have higher sex steroid levels than boys, possibly leading to earlier puberty.

Male hormones like testosterone may make COVID-19 worse, and testing for sensitivity to these hormones could help predict how severe a patient's symptoms might be. Treatments that reduce these hormones are being explored.

Hirsutism, excessive male-pattern hair in women, can be caused by high androgens or skin sensitivity, diagnosed by testosterone levels, and treated with hair removal and hormone therapy.

Consider Sertoli-Leydig cell tumors in Peutz-Jeghers syndrome patients with adnexal masses.

Injectables can feminize or masculinize a transgender person's face, but more research is needed for best practices.

Using testosterone-stimulated weanling rats can effectively replace castrated rats for anti-androgen testing, reducing animal stress.

An unusual growth of Leydig cells in a woman's ovaries caused her excessive hair growth, which was treated successfully with surgery.

Significant facial gender transformation requires surgery, not nonsurgical methods.

Finasteride may treat baldness but less effective for those with 5α-reductase deficiency.

Trichothiodystrophy can be linked to urologic issues and high calcium in urine.

Finasteride is safe and effective for hair loss in transgender men, but may affect testosterone therapy.

Two women with very high androgen levels had only slight skin issues, one due to a non-classical adrenal disorder and the other due to an adrenal tumor.

A young woman had a rare tumor causing high male hormone levels and symptoms like excessive hair and acne. After removing the tumor, her hormone levels returned to normal. Early diagnosis is important.

Early sexual development in children, especially girls, can be treated with hormone therapy to improve adult height and requires support for the child and family.

Elevated testosterone, DHEA-S, and FAI help identify PCOS risk in menstrual irregularities.

Ciclosporin can cause excessive hair growth even with testosterone blockers.

Adding estrogen increased bone mass in a transsexual man undergoing hormone therapy.

Transgender patients face unique skin issues due to hormone treatments and surgeries.

The conclusion is that published guidelines are improving transgender medical care, but more research and education in transgender medicine are needed.

Benign ovarian tumors can cause excess male hormones and related conditions in postmenopausal women.

Facial contouring is crucial for the satisfaction and well-being of Chinese transgender females.

Postmenopausal hyperandrogenism involves excess male hormones causing symptoms like hair growth and acne, and requires ruling out tumors and other disorders.

Hirsutism is excessive male-pattern hair growth in women, often caused by hormonal imbalances, and requires ongoing treatment to manage.

Prepubertal girls with hypertrichosis have more sensitive androgen receptors, leading to increased body hair growth.

The letter suggests testosterone replacement therapy might worsen COVID-19 outcomes.

Some men with early hair loss may have a male version of PCOS, affecting hormones and increasing health risks.

A woman's hair loss and other symptoms were due to a rare hormone deficiency treatable with steroids.

A castrated dog developed hair loss and prostate issues from long-term exposure to estrogen cream.