research Reversible decreases of fertility in male Sprague-Dawley rats treated orally with finasteride, a 5α-reductase inhibitor
Finasteride temporarily lowers male rat fertility without affecting libido.
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660-690 / 1000+ results research Sex-Chromosome-Related Dimorphism in Steroidogenic Enzymes and Androgen Receptor in Response to Testosterone Treatment: An In Vitro Study on Human Primary Skeletal Muscle Cells
Chromosomal differences affect how muscle cells respond to testosterone.
research Exogenous Testosterone (T) Alone or with Finasteride Increases Physical Performance, Grip Strength, and Lean Body Mass in Older Men with Low Serum T
Testosterone therapy improves physical function, strength, and body composition in older men with low testosterone levels.
research A pharmacovigilance study of drug‐reduced male semen quality based on the Food and Drug Administration adverse event reporting system database
Some drugs can reduce male semen quality.
research EFFECT OF LOW DOSE FINASTERIDE ON SEMEN VOLUME AND SPERM DENSITY IN YOUNG MEN
research Physiological and histological study of the effect of finasteride drug (Prostacare) on the fertility of albino male rats
Finasteride significantly reduces fertility in male rats.
research Propecia-induced spermatogenic failure: a report of two cases
Stopping finasteride improved sperm counts in two men, reducing the need for fertility treatments.
research The role of benign prostatic hyperplasia treatments in ejaculatory dysfunction
Treatments for enlarged prostate can cause problems with ejaculation, and less invasive options might preserve sexual function better.
research Hormonal status of male reproductive system: androgens and estrogens in the testis and epididymis. In vivo and in vitro approaches.
Androgens and estrogens are crucial for male reproductive health, affecting hormone levels and tissue function.
research Finasteride use in the male infertility population: effects on semen and hormonal parameters
Finasteride may improve sperm count in subfertile men with low sperm count.
research The Effects of Perinatal Androgen Deprivation on Sexual Motivation in Male Rats
Blocking androgens at birth reduces sexual motivation in male rats.
research Finasteride and male infertility: a case for prospective collaborative research databases?
Finasteride discontinuation increases sperm count in men.
research Disruption of androgen metabolism, regulation and effects : involvement of steroidogenic enzymes
Anabolic steroids and inflammation can disrupt androgen metabolism, potentially causing health issues.
research Re: The Efficacy of Dihydrotestosterone Transdermal Gel Before Primary Hypospadias Surgery: A Prospective, Controlled, Randomized Study
Dihydrotestosterone gel before hypospadias surgery led to less scarring but raised concerns about potential psychological effects and skin changes.
research Effects of Abuse of Anabolic Androgenic Steroids on Iraqi Athletes
Abuse of anabolic steroids in Iraqi athletes leads to negative effects on hormones, liver and kidney function, blood sugar, and cholesterol levels.
research Testosterone up-regulates vacuolar ATPase expression and functional activities in vas deferens of orchidectomized rats
Testosterone increases acidification in the vas deferens by up-regulating V-ATPase.
research Case report: a study of the clinical characteristics and genetic variants of post-finasteride syndrome patients
Finasteride may cause lasting sexual and mental health issues, and genetic screening could help prevent them.
research Ejaculatory dysfunction in the treatment of lower urinary tract symptoms
Treatments for urinary symptoms often cause ejaculatory problems.
research Is age at puberty associated with semen quality and reproductive hormones in young adult life?
Men who start puberty later may have lower sperm quality and different hormone levels in adulthood.
research Advances in male hormone substitution therapy
New treatments for low male hormones improved sexual function and mood but had unclear risks, especially for older men.
research Associations between semen quality and lower urinary tract symptoms in ageing male
The conclusion is that doctors should be careful when prescribing 5α-reductase inhibitors due to possible serious side effects, and they should discuss these risks with patients.
research The articulations of Adam's rib with the lower urinary tract
The patient had complex urinary tract issues and ambiguous genitalia, with physical features suggesting a hormonal imbalance.
research Psychosocial Impairment as a Possible Cause of Sexual Dysfunction among Young Men with Mild Androgenetic Alopecia: A Cross-sectional Crowdsourcing Web-based Study.
Young men with mild hair loss who experience significant social and emotional distress are more likely to have sexual problems.
research Medicolegal aspects of doping in football
Doping in football faces legal challenges with testosterone limits, hair loss treatments, and recreational drug use.
research Decision letter: Effects of lifelong testosterone exposure on health and disease using Mendelian randomization
Increased free testosterone can lead to stronger bones and less body fat but also higher risks of prostate cancer, hair loss, spine issues, and high blood pressure.
research The postnatal offspring of finasteride-treated male rats show altered ERα and PCNA expression in the liver
Finasteride use in male rats may harm their male offspring's liver function.
research Adverse Event Reporting in Clinical Trials of Finasteride for Androgenic Alopecia: A Meta-analysis.
Finasteride for hair loss may cause long-lasting side effects like impotence and low libido, but trials lack proper safety reporting.
research Regression of Pathologic Changes Induced by the Long-term Administration of Contraceptive Steroids to Rodents
Some steroid-induced health issues in rodents improved after stopping treatment, but hair loss and eye problems did not.
research The Effects of Perinatal Androgen Deprivation on Body Weight and Spatial Working Memory in Male Rats
Blocking male hormones in baby rats improved memory and increased weight.
research Low serum testosterone is associated with an increased risk of first-time renal calculi in men without testosterone replacement therapy
Low testosterone increases kidney stone risk in men not on testosterone therapy.