research Safety of testosterone treatment in postmenopausal women
Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.
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930-960 / 1000+ results research Generating Disulfides in Multicellular Organisms: Emerging Roles for a New Flavoprotein Family
QSOX enzymes help form protein bonds in cells, especially in tissues with high secretory activity.
research Testosterone, Dihydrotestosterone, and Incident Cardiovascular Disease and Mortality in the Cardiovascular Health Study
DHT may increase the risk of heart disease and death in elderly men.
research Effect of High Levels of Testosterone on Cardiovascular Risk in Polycystic Ovary Syndrome (PCOS)
High testosterone increases heart disease risk in women with PCOS.
research CATALASE INTRINSIC EMISSIONS OF ELECTROMAGNETIC FIELDS AS PROBABLE CAUSE IN CANCEROGENESIS FROM CONSUMPTION OF RED AND PROCESSED MEAT
Catalase in processed meats may increase cancer risk due to electromagnetic emissions.
research Androgen profile in Chinese women with polycystic ovary syndrome in their reproductive years
Chinese women with PCOS have higher androgen levels, which change with age and weight.
research Human hair keratin responds to oxidative stress via reactive sulfur and supersulfides
Human hair strength and health are linked to sulfur compounds that can be reduced by stress but improved with sulfur supplements.
research 5α-reductase isoenzymes mediate stress-exacerbated Tourette-like responses in animal models
Targeting 5α-reductase type 1 may help manage Tourette-like symptoms.
research Comparison of the impact of intermittent fasting diet alone or in conjunction with probiotic supplementation versus calorie-restricted diet on inflammatory, oxidative stress, and antioxidant capacity biomarkers in women with polycystic ovary syndrome: A randomized placebo-controlled trial
Intermittent fasting, with or without probiotics, doesn't improve inflammation or stress markers in women with PCOS compared to calorie restriction.
research Estrogenic Potential of 2-Alkyl-4-(thio)chromenone 6-O-Sulfamates: Potent Inhibitors of Human Steroid Sulfatase
A substance called Compound 2g can strongly block STS (a hormone-related enzyme) without affecting estrogen levels, making it potentially good for treating breast cancer.
research Association between prostate‐specific antigen and serum testosterone: A systematic review and meta‐analysis
Testosterone replacement therapy, especially intramuscular, raises PSA levels, but no overall link between PSA and testosterone was found except in non-BPH patients.
research Cardiovascular risks and elevation of serum DHT vary by route of testosterone administration: a systematic review and meta-analysis
Oral testosterone therapy raises heart risk more than other methods.
research Oxidative DNA Damage Accelerates Skin Inflammation in Pristane-Induced Lupus Model
Loss of OGG1 increases skin inflammation and auto-antibodies in lupus.
research Daily subcutaneous testosterone for management of testosterone deficiency
Daily subcutaneous testosterone effectively restores testosterone levels in men.
research Androgens in postmenopausal women
Testosterone in older women can increase bone density, muscle mass, fat mass, improve memory, and boost libido, but may cause nipple color changes.
research Effects of androgen on extracellular vesicles from endothelial cells in rat penile corpus cavernosum
Low androgen levels reduce nitric oxide production in rat penile cells.
research Sex hormones modulate pathogenic processes in experimental traumatic brain injury
Sex hormones affect brain injury differently in males and females.
research 7288 A Preclinical Mouse Model of Gender-Affirming Hormone Therapy: Metabolic and Behavioral Outcomes
Gender-affirming hormone therapy affects metabolism differently based on treatment type.
research Regional Variation in Androgen Receptor Expression and Biomechanical Properties May Contribute to Cryptorchidism Susceptibility in the LE/orl Rat
Differences in androgen receptor expression and tissue properties may lead to higher cryptorchidism risk in certain rats.
research Prostaglandin D2 Uses Components of ROS Signaling to Enhance Testosterone Production in Keratinocytes
Prostaglandin D2 increases testosterone production in skin cells through a process involving reactive oxygen species, and antioxidants may help treat hair loss.
research Salivary testosterone levels in infertile men
Men with low or no sperm count have lower salivary testosterone levels, and saliva testing can measure their testosterone well.
research Intracrine and Myotrophic Roles of 5α-Reductase and Androgens
Muscles can make their own androgens, which may help muscle growth.
research Dehydroepiandrosterone (DHEA) and Testosterone Concentrations in Human Hair after Chronic DHEA Supplementation
Chronic DHEA supplementation slightly increases testosterone in hair but stays within safe limits.
research Effects of Testosterone on the Expression of Connexin 26 and Connexin 43 in the Uterus of Rats During Early Pregnancy
Testosterone changes important cell communication proteins in pregnant rats' uteruses, which might affect pregnancy success.
research Protective Effects of BCC Against Oxidative Stress in Cardiomyocyte Cells
BCC can protect heart cells from damage caused by oxidative stress.
research Induction of transforming growth factor-beta 1 by androgen is mediated by reactive oxygen species in hair follicle dermal papilla cells
Androgens increase a growth factor in hair cells by creating reactive oxygen species, and antioxidants might help treat hair loss.
research Testosterone Therapy for Osteoporosis in Men
Testosterone therapy may help men with osteoporosis.
research Androgenic modulation of arterial baroreceptor dysfunction and neuroinflammation in endotoxic male rats
Testosterone affects blood pressure control and inflammation in male rats with endotoxic shock, and blocking certain hormones may help treat it.
research Effects of Testosterone+Finasteride On Muscle After Spinal Cord Injury: A Randomized Double-Blind, Placebo-Controlled Pilot Study
Testosterone and finasteride improve muscle strength and size after spinal cord injury.
research The role of Paraoxonase 1 in Alopecia Areata, a Marker and a Severity Index
Lower Paraoxonase 1 levels in alopecia areata patients suggest antioxidant treatment might help.