59 citations
,
May 2014 in “Expert Opinion on Therapeutic Targets” The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.
51 citations
,
January 2001 in “Biological & Pharmaceutical Bulletin” The bark of Myrica rubra contains compounds that can block testosterone effects and might help prevent hair loss.
45 citations
,
February 2001 in “Joint bone spine” Gonadal dysgenesis, like Turner's and Klinefelter's syndromes, negatively affects bone health, but hormone treatments can help.
44 citations
,
March 2012 in “Fitoterapia” Germacrone from Curcuma aeruginosa may help treat conditions related to male hormones by blocking a specific enzyme.
44 citations
,
December 2005 in “The Journal of Steroid Biochemistry and Molecular Biology” Combining 5α-reductase and aromatase inhibitors may better reduce estrogen levels.
40 citations
,
March 1982 in “British Journal of Dermatology” Young women with diffuse hair loss may have low SHBG levels, which could lead to more active testosterone and contribute to their hair loss.
36 citations
,
March 2007 in “Journal of Chromatography B” Hair analysis can detect testosterone in horses after drug administration.
28 citations
,
February 2011 in “Clinical Endocrinology” Women with PCOS have unhealthy changes in their cholesterol particles that are not related to their body weight.
20 citations
,
June 2010 in “International Journal of Dermatology” Women with mild acne are more likely to have polycystic ovary syndrome (PCOS) than those without acne.
17 citations
,
June 2010 in “Journal of Cosmetic Dermatology” Many women with hard-to-treat acne also have PCOS.
11 citations
,
September 2020 in “OncoTargets and Therapy” Dihydrotestosterone increases growth and spread of human brain cancer cells, and blocking its formation might help treat this cancer.
11 citations
,
August 2009 in “Expert Opinion on Drug Discovery” We need better ways to test and understand SARMs to make safer and more effective treatments.
10 citations
,
October 1992 in “Hormone and Metabolic Research” Finasteride safely lowers DHT levels without affecting hormone levels, helping with conditions like enlarged prostate, acne, and hair loss.
9 citations
,
January 1997 in “Endocrine Journal” Gonadal biopsy is the best method to diagnose gonadal dysgenesis.
8 citations
,
February 2014 in “General and Comparative Endocrinology” Finasteride affects frog testes by increasing testosterone, decreasing 5α-DHT, and impacting genes related to reproduction and other functions.
8 citations
,
February 2010 in “Journal of Dermatology” A topical treatment safely and effectively reduced acne by causing targeted cell death in sebaceous glands without side effects.
5 citations
,
January 2014 in “Postepy Dermatologii I Alergologii” Hormonal treatments like birth control pills can improve acne in women with excess hair growth and hormone imbalances.
3 citations
,
April 2019 in “Human & Experimental Toxicology” Finasteride causes harmful organ changes in female mice.
2 citations
,
August 2020 in “JCRPE” A girl with Denys-Drash syndrome was misdiagnosed due to biotin affecting her hormone test results.
1 citations
,
June 2021 in “Singapore Medical Journal” Dutasteride and finasteride can help increase hair growth gene expression but need further improvement.
1 citations
,
March 2021 in “Phytomedicine plus” Cernitin™, a pollen extract, was found to significantly reduce pain and inflammation in rats with chronic prostatitis, suggesting it could be a useful alternative to certain anti-inflammatory drugs.
1 citations
,
December 2010 in “Elsevier eBooks” Cell transplantation faces challenges in genitourinary reconstruction, but alternative tissue sources and microencapsulation show promise.
Androstenedione is better than testosterone for diagnosing PCOS in Indian women.
January 2024 in “Institutional Repositories DataBase (IRDB)” The method accurately measures steroid hormones in hair to study hormone dynamics related to hair loss.
July 2023 in “Journal of Microbiology and Biotechnology” Terminalia bellirica extract may help promote hair growth and prevent hair loss caused by testosterone.
May 2017 in “Endocrine Abstracts” Testosterone levels are not linked to erectile dysfunction in young and middle-aged men with HIV.
The document concludes that accurate diagnosis and management of PCOS are crucial due to its associated health risks.
May 2003 in “Journal of Investigative Dermatology” The meeting covered advances in understanding hair growth, causes of hair loss, and potential treatments.
110 citations
,
April 2002 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” Dihydrotestosterone gel improved well-being and sexual function in older men without negatively affecting prostate health.
49 citations
,
September 1986 in “British Journal of Dermatology” Hidradenitis suppurativa improves with antiandrogen therapy.