research Clinical use of 5α-reductase inhibitors
Finasteride effectively treats hair loss and enlarged prostate in men, with mild side effects.
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960-990 / 1000+ results research Simultaneous pharmacokinetic and pharmacodynamic analysis of 5α-reductase inhibitors and androgens by liquid chromatography tandem mass spectrometry
The method effectively measures drug impact on DHT levels in prostate treatments.
research The novel drug CS-891 inhibits 5alpha-reductase activity in freshly isolated dermal papilla of human hair follicles.
CS-891 may effectively treat hair loss by blocking enzymes in hair follicles.
research The enzyme and inhibitors of 4-ene-3-oxosteroid 5α-oxidoreductase
Inhibitors of the enzyme 5 alpha-reductase could potentially treat disorders like prostate cancer and baldness.
research Evaluation of the effectiveness of androgenetic alopecia treatment in men us- ing platelet-rich plasma: A systematic review of randomized, placebo-con- trolled trials
PRP treatment significantly increases hair density in men with androgenetic alopecia.
research Selective androgen receptor modulators: a critical appraisal
SARMs show promise but need more evidence to prove they're better than traditional androgens.
research Connarus semidecandrus Jack Exerts Anti-Alopecia Effects by Targeting 5α-Reductase Activity and an Intrinsic Apoptotic Pathway
Connarus semidecandrus Jack extract promotes hair growth and thickness, reduces prostate cancer cell growth, and could potentially be used as a treatment for hair loss.
research Novel natural lipids based NLC containing finasteride improved androgenetic alopecia treatment in rats
Finasteride in lipid carriers improved hair growth in rats.
research An overview on 5α-reductase inhibitors
5α-reductase inhibitors, like Finasteride and Dutasteride, help manage benign prostatic hyperplasia.
research Sperm extraction in nonmosaic Klinefelter syndrome patients: A case series and literature review of sperm extraction in Klinefelter syndrome patients
Younger Klinefelter Syndrome patients have a better chance of successful sperm extraction.
research Effects of dietary supplements on androgenetic alopecia: a systematic review and network meta-analysis
Certain dietary supplements can improve hair density and are well-tolerated for treating androgenetic alopecia.
research (7E)-7,8-Dehydroheliobuphthalmin from Platycladus orientalis L.: Isolation, Characterization, and Hair Growth Promotion
DHHB from Platycladus orientalis L. promotes hair growth and could be a natural alternative to current treatments.
research Jiawei Erzhiwan Ameliorates Androgenetic Alopecia by Regulating the SIRT1/JNK/p38 MAPK Pathway
Jiawei Erzhiwan helps hair growth in androgenetic alopecia by affecting specific cell pathways.
research Topical cetirizine for the management of androgenic alopecia: Results of a pilot study
Topical cetirizine may help increase hair length in male pattern baldness and could be an alternative to minoxidil with fewer side effects.
research Evaluating the diagnostic accuracy of androgen measurement in polycystic ovary syndrome: a systematic review and diagnostic meta-analysis to inform evidence-based guidelines
Androgen measurement helps diagnose PCOS, but accuracy varies, needing standard methods.
research Female pattern hair loss—An update
Female pattern hair loss has multiple causes and treatments, with new therapies showing promise.
research Steroid Sulfatase Deficiency and Androgen Activation Before and After Puberty
In STSD patients, the body compensates for low androgen levels by increasing another enzyme's activity.
research Gender Differences in Response to COVID-19 Infection and Vaccination
Men generally face more severe COVID-19 outcomes than women, partly due to hormonal differences.
research Late bedtime was associated with increased androgen and reduced lean mass in women with polycystic ovary syndrome: a cross-sectional study
Going to bed late may increase hormones and decrease muscle in women with PCOS.
research Phytochemicals With Anti 5-alpha-reductase Activity: A Prospective For Prostate Cancer Treatment
Plant-based compounds might be effective, low-side-effect treatments for prostate cancer by blocking a specific enzyme.
research Recent Advances in the Role of Fibroblast Growth Factors in Hair Follicle Growth
Fibroblast growth factors could be a better, safer treatment for hair loss than current options.
research Phytochemicals With Anti 5-alpha-reductase Activity: A Prospective For Prostate Cancer Treatment
Plant-based compounds may offer safer prostate cancer treatment with fewer side effects.
research Exploring the Impact of the Microbiome on Neuroactive Steroid Levels in Germ-Free Animals
Gut microbes significantly affect brain steroid levels.
research Regenerative medicine strategies for hair growth and regeneration: A narrative review of literature
New regenerative treatments for hair loss show promise but need more research for confirmation.
research Evaluation of the efficacy and toxicity of oral and topical pumpkin oil on the hair growth of mice
Pumpkin seed oil promotes hair growth and improves hair texture without harmful effects.
research Biomedical Technologies for Androgenic Alopecia Treatment: Advance, Mechanism and Future Direction
New technologies show promise for safer, more effective hair loss treatments.
research Phytochemicals and novel delivery systems in alopecia management: An integrative review
Combining herbal medicines with modern delivery systems may improve alopecia treatment.
research Keyora Integrated Nutritional Modulation of the Redox–NO–Androgen Axis in Male Endocrine, Reproductive, and Metabolic Disorders
Nutritional interventions can help restore balance in male health by targeting oxidative stress and hormonal issues.
research BH14 Bald-faced lies: a qualitative review of misinformation on alopecia
Misinformation about alopecia is common online and can harm patient choices.
research Gender Differences in the Regulation of Blood Pressure
Men generally have higher blood pressure than premenopausal women, but postmenopausal women's blood pressure can surpass men's, and hormone therapy doesn't significantly help.