2 citations
,
August 2013 in “The Lancet. Diabetes & endocrinology” The FDA rejected a testosterone drug again due to safety concerns.
The FDA did not approve a testosterone drug because of safety concerns.
January 2026 in “International Journal of Molecular Sciences” Lifestyle changes and environmental strategies can help address declining testosterone levels.
40 citations
,
November 2011 in “American Journal of Human Biology” Stress from being transgender is linked to higher blood pressure at night and more inflammation, which may affect heart health.
October 2022 in “Zenodo (CERN European Organization for Nuclear Research)” Truman Plus Male Enhancement is marketed as a natural testosterone booster to improve men's sexual health and energy.
241 citations
,
March 2000 in “The Journal of Urology” Men over 50 may experience hormone decline causing various symptoms, and proper management is crucial.
63 citations
,
January 2010 in “Frontiers in Aging Neuroscience” 3α-androstanediol helps reduce age-related cognitive and mood declines in male rats, unlike testosterone.
26 citations
,
March 2001 in “PubMed” Men's fertility and sexual health decline with age, with reduced testosterone and virility, and many lose fertility by their eighties.
February 2026 in “Tạp chí Sức khỏe và Lão hóa” Hormones play a key role in skin aging, with estrogen and testosterone declines affecting skin health.
Menopause is a clear hormonal transition in women, while men experience a gradual testosterone decline, with some needing lifestyle changes and targeted therapy.
February 2016 in “PubMed” Properly administered testosterone therapy is safe and effective but often not covered by insurance.
186 citations
,
February 2015 in “Frontiers in Neuroscience” Testosterone affects brain behavior in complex and varied ways.
42 citations
,
July 1982 in “PubMed” Loestrin effectively normalizes testosterone levels and improves PCOS symptoms with minimal side effects.
28 citations
,
October 1998 in “Baillière's clinical endocrinology and metabolism” Testosterone replacement may help post-menopausal women with androgen insufficiency, but more research is needed on its benefits and risks.
2 citations
,
November 2019 in “Case reports in women's health” Ovarian vein sampling helped diagnose rare ovarian tumors causing high testosterone, and surgery to remove the tumors lowered the testosterone levels.
3 citations
,
March 2019 in “Post Reproductive Health” Testosterone replacement can help menopausal women with various symptoms, but should be used carefully and is not yet officially licensed in the UK for women.
105 citations
,
June 2010 in “The journal of sexual medicine” Testosterone undecanoate increases lean mass and causes various physical changes in female-to-male transsexuals.
41 citations
,
September 2010 in “British journal of dermatology/British journal of dermatology, Supplement” Both intense pulsed light and long-pulsed diode laser effectively reduced facial hair in women, with no significant difference in satisfaction after 6 months, but intense pulsed light was more painful.
Testosterone works in different ways, including direct interaction with its receptor, conversion to other hormones for specific effects on genitalia, hair, bones, and muscle, and changes in body fat and sexual function when low.
September 2014 in “Springer eBooks” Men and women experience skin aging differently due to changes in sex hormone levels with age.
129 citations
,
February 2006 in “Andrology” Men with low testosterone should be carefully evaluated and monitored before and during treatment.
10 citations
,
October 2017 in “Dermatologic clinics” Aging in men is influenced by genetics and lifestyle, leading to muscle loss, bone issues, and skin damage.
April 2014 in “Journal of evolution of medical and dental sciences” Women over forty can maintain skin and hair health with lifestyle and dietary changes.
August 2022 in “Journal of drugs in dermatology” Hormone therapy might help improve women's appearance as they age.
6 citations
,
September 1998 in “The Journal of The British Menopause Society” Testosterone replacement may help postmenopausal women with sexual function and bone density, but suitable treatments are limited.
October 2022 in “Zenodo (CERN European Organization for Nuclear Research)” Truman Plus Male Enhancement may help boost testosterone and improve sexual health, but severe cases need medical treatment.
51 citations
,
April 1999 in “The Journal of Steroid Biochemistry and Molecular Biology” Testosterone replacement may improve sexual desire and bone health in women with low androgen levels, but more research is needed on its long-term safety.
28 citations
,
May 2013 in “The Journal of Steroid Biochemistry and Molecular Biology” Testosterone therapy can improve sexual desire and function in postmenopausal women but should be used cautiously and not based solely on testosterone levels.
26 citations
,
January 2020 in “Przegląd Menopauzalny” Menopausal women have higher androgen levels, which can cause symptoms like facial hair growth and low sexual desire.
20 citations
,
January 2003 in “Treatments in Endocrinology” Testosterone therapy can help improve mood, sexual function, and bone health in women with low androgen levels, but more research is needed to establish safe and effective guidelines.