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Testosterone replacement therapy improved blood sugar and fat levels without raising prostate cancer risk in Japanese men with low testosterone.

Testosterone undecanoate safely and effectively increased penis size in male children with 5-alpha-reductase deficiency.

5α-Reductase inhibitors do not consistently increase testosterone levels in the blood.

Testosterone is important for male sexual traits, reproduction, muscle and bone health, blood production, and metabolism, and works both directly and after being changed into other hormones.

Testosterone and dihydrotestosterone slow hair cell growth, while estradiol has no effect.

Testosterone therapy in transgender individuals can increase the risk of erythrocytosis.

Testosterone therapy can improve sexual satisfaction and mood in surgically menopausal women when used with estrogen, but its long-term safety and effects on naturally menopausal and premenopausal women are unclear.

Testosterone use for muscle growth can cause hair loss in males.

Both injectable contraceptives lower testosterone and SHBG levels, with NET-EN having a greater effect than DMPA-IM.

Low testosterone increases kidney stone risk in men not on testosterone therapy.