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The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.

Sports supplements can cause skin problems and may contain harmful substances.

Testosterone replacement can help women with low libido and mood, but they need to have enough estrogen first to avoid side effects.

CRH promotes fat production in skin cells, affecting conditions like acne.

High levels of 3 alpha-diol glucuronide in the blood are a marker of increased androgen action in women with excessive hair growth of unknown cause.

Hormonal male contraception is effective and could be market-ready, but more research is needed to ensure safety for all ethnic groups.

There are various effective hormone treatments for puberty induction in boys and girls with hypogonadism, and starting treatment early is important.

The method accurately measures hormones and endocannabinoids in mice, showing gut microbiota diversity affects these levels and may influence stress and reproductive systems.

Significant progress was made in understanding androgen excess disorders, but much is still unknown.

Steroid 5α-reductase evolved from protists and diversified in eukaryotes, with specific roles in mammals and plants.

Modified frameworks with stearic acid enhance drug delivery and promote hair growth.

Minoxidil can help transgender males grow facial hair before starting testosterone therapy.

Vitamin D is needed for metformin to lower prolactin effectively.

A new treatment using microneedles with black phosphorus and laser helps regrow hair effectively and safely.

A new microneedle patch helps treat hair loss by improving drug delivery to hair follicles.

Topical finasteride might be a good alternative for hair loss treatment with fewer side effects, but more research is needed.

Abusing steroids can damage your heart, muscles, reproductive system, liver, skin, and brain, and may increase the risk of Alzheimer's disease.

Platelet-rich Plasma (PRP) helps treat hair loss effectively, especially when prepared using the double-spin method.

The document concludes that personalized hormonal treatments are important for transgender individuals and more research is needed for non-binary treatments.

Natural products show promise for new hair loss treatments.

The engineered yeast strain BLYAS can quickly and sensitively detect androgenic chemicals.

A combination of desogestrel and ethinyl oestradiol effectively reduces hair growth in hirsute women.

Females have stronger immune responses to COVID-19 than males, leading to better outcomes.

Mouse genital development depends on male or female hormones for specific features.

Understanding how DHT works is important for diagnosing and treating hormone-related disorders.

Body hair isn't a good substitute for scalp hair in steroid analysis.

Finasteride, a hair loss drug, may cause long-term sexual side effects due to changes in hormone receptor levels.

Some antiandrogens may lower testosterone better than others, but it's unclear which is best for feminization in transgender women; more research is needed.

Pioglitazone improved insulin sensitivity and altered cortisol metabolism in PCOS patients.

Testosterone increases 3α-androstanediol levels, which can be blocked by finasteride.