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NKIRAS2 can suppress certain skin tumors but its effect on cancer varies with context and expression level.

A gene mutation in mice causes permanent hair loss and skin issues.

ΔNp63α stops TAp73β from working in skin cancer by blocking its access to specific genes, not by directly interacting with it.

A WNT10A gene mutation leads to ectodermal dysplasia by disrupting cell growth and differentiation.

Transit-amplifying cells are crucial for tissue repair and can contribute to cancer when they malfunction.

ETC-159 was safe up to 30 mg, but no tumor shrinkage was seen.

HEY2+ cells help regenerate skin during wound healing.

Activating β-catenin increases melanocytes and decreases Schwann cells.

mrp/plf-mRNA can indicate tumor-promoting effects in skin.

Twist1 helps maintain important features of cells crucial for hair growth by working with Tcf4 and β-catenin.

Mutations in β1 integrins cause embryonic death but have milder effects on skin.

Whiskers can form without sensory nerves or Foxd1, thanks to Meis2 in mesenchymal cells.

Monilethrix is linked to a gene cluster on chromosome 12.

Csdc2 helps hair growth in cashmere goats by regulating specific genes.

Putting thymidine dinucleotide on newborn mice's skin can delay and reduce skin cancer.

The study created a mouse model to better understand hair follicle stem cells' role in hair growth and repair.

The LEF-1 binding site enhances gene expression in hair follicles, with other proteins aiding specific regulation.

Memory regulatory T cells need IL-7, not IL-2, to stay in peripheral tissues.

Targeting THY1 can improve skin repair and healing.

Super-enhancers control CD25 expression in specific cell types, affecting immune function.

Akt2 and SGK3 are both important for normal hair growth and development.

HT-scCAT-seq helps understand gene regulation in embryonic skin development.

High glycine–tyrosine keratin-associated proteins help make hair strong and maintain its shape.

THAP1 gene changes do not affect DYT1 dystonia; finasteride may help reduce tics and OCD in Tourette syndrome.

The new model helps understand and develop treatments for genetic skin disorders like AEC.

The IRF2BP2 gene affects sheep fleece quality by influencing fiber traits.

Fzd2 is important for skin and hair development through various signaling ways.

Lack of TrkC receptor delays hair follicle development.