October 2023 in “Biomedical science and engineering” Innovative methods are reducing animal testing and improving biomedical research.
November 2021 in “International Journal for Research in Applied Science and Engineering Technology” Lyophilized platelet-rich plasma is beneficial and effective for various medical treatments, including tissue regeneration and hair regrowth.
667 citations
,
May 2008 in “Genes & Development” Histone demethylases can change gene expression and may be linked to diseases like cancer.
479 citations
,
January 2005 in “BioEssays” Hair follicle development is controlled by interactions between skin tissues and specific molecular signals.
218 citations
,
April 2008 in “Genes & Development” Skin stem cells help repair damage and maintain healthy skin.
144 citations
,
September 2012 in “Genes & development” Aging causes skin stem cells to work less effectively.
82 citations
,
May 2009 in “Development” EGF and KGF signalling prevent hair follicle formation and promote skin cell development in mice.
28 citations
,
July 2007 in “Development” TAF4 is important for skin cell growth and helps prevent skin cancer in mice.
12 citations
,
March 2018 in “Bioengineering” The document concludes that products like PRP and PRF show promise for tissue healing, but evidence of their effectiveness is inconsistent.
8 citations
,
February 2023 in “American Journal of Physiology-Cell Physiology” Adiponectin and bradykinin play important roles in skin health and may help treat skin conditions.
6 citations
,
February 2021 in “Frontiers in Cell and Developmental Biology” Eating too much or too little vitamin A can cause hair loss.
4 citations
,
January 2020 in “Cells” The research found that the gene activity in mouse skin stem cells changes significantly as they age.
3 citations
,
May 2023 in “Current Molecular Medicine” PRP is not a stem cell treatment and should not be marketed as such.
3 citations
,
December 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” The research reveals how early embryonic mouse skin develops from simple to complex structures, identifying various cell types and their roles in this process.
1 citations
,
December 2023 in “Curēus” Tadalafil is effective for treating urinary symptoms in men with BPH.
1 citations
,
September 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Removing Dicer from pigment cells in newborn mice causes early hair graying and changes in cell migration molecules.
March 2026 in “Frontiers in Immunology” Regulatory T cells help heal skin wounds by reducing inflammation and promoting tissue repair.
Cellular flows and tissue mechanics guide feather follicle formation in birds.
Dexamethasone-primed stem cell media shows promise in treating lupus by reducing symptoms and inflammation.
December 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Aged individuals heal wounds less effectively due to specific immune cell issues.
November 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Disrupted cholesterol production impairs hair follicle stem cells, leading to hair loss.
October 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Immune cells are essential for early hair and skin development and healing.
September 2023 in “Curēus” Reproductive hormones play a crucial role in breast cancer development and treatment challenges.
September 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Freezing gamma-irradiated amniotic fluid may help hair growth and speed up the growth phase.
70 citations
,
August 2020 in “Nanomaterials” Electrospun nanofibers show promise for enhancing blood vessel growth in tissue engineering but need further research to improve their effectiveness.
69 citations
,
April 2019 in “Biomedicines” PRP and HF-MSCs treatment improves hair growth, thickness, and density in androgenetic alopecia.
19 citations
,
June 2020 in “Animals” Poor maternal nutrition can lead to fewer wool follicles in Chinese Merino sheep.
1 citations
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November 2025 in “Frontiers in Immunology” More research is needed to understand and manage rheumatoid arthritis better.
February 2026 in “Journal of Integrative Neuroscience” NGF-modified hair follicle stem cells may help treat Alzheimer's by improving brain function and reducing harmful proteins.
November 2025 in “Frontiers in Immunology” Immune cells are crucial for normal skin development and their dysfunction can cause skin disorders.