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To Identify the Expression of Intracellular Toll-Like Receptors in Peripheral Blood Mononuclear Cells of Alopecia Areata

research TO IDENTIFY THE EXPRESSION OF INTRACELLULAR TOLL-LIKE RECEPTORS (TLRS) IN PERIPHERAL BLOOD MONONUCLEAR CELLS OF ALOPECIA AREATA

November 2023

Alopecia areata patients have higher levels of certain immune receptors, suggesting new treatment possibilities.

research Immortalized human hair follicle-derived mesenchymal-like stromal cells for the long-term production of scalable Immunomodulatory and regenerative secretome

1 citations , November 2025 in “Stem Cell Research & Therapy”

Immortalized hair follicle cells could be useful for regenerative medicine and treating inflammation and oxidative stress.

research Controlled Delivery of T-box21 Small Interfering RNA Ameliorates Autoimmune Alopecia (Alopecia Areata) in a C3H/HeJ Mouse Model

69 citations , February 2008 in “The American journal of pathology”

Controlled delivery of specific RNA and IL-4 restored hair growth in mice with autoimmune alopecia.

research 001 Human scalp hair follicles are protected from alopecia areata in vivo by regulatory γδT cells

November 2024 in “Journal of Investigative Dermatology”

γδT cells can protect hair follicles from alopecia areata and promote hair regrowth.

research Tissue Resident Foxp3+ Regulatory T Cells: Sentinels and Saboteurs in Health and Disease

9 citations , March 2022 in “Frontiers in Immunology”

Foxp3+ Regulatory T Cells are important for immunity and tolerance, affect hair growth and wound healing, and their dysfunction can contribute to obesity-related diseases and other health issues.

research PREVENTION OF GRAFT-VERSUS-HOST DISEASE BY INTRATHYMIC INJECTION OF RECIPIENT-TYPE SPLENOCYTES INTO DONOR1

2 citations , November 1996 in “Transplantation”

Injecting recipient splenocytes into donors' thymus can prevent graft-versus-host disease.

Expanding The Phenotype Of Hyper-IgE Syndrome: Heterozygous Variant In IL6ST With Elevated Serum IgE And Isolated Abscesses

research P378: Expanding the phenotype of hyper-IgE syndrome: Heterozygous VUS in IL6ST with elevated serum IgE and isolated abscesses

January 2024 in “Genetics in Medicine Open”

A new IL6ST gene variant may cause a unique form of hyper-IgE syndrome with skin abscesses and high IgE levels.

research Interleukin 6 and STAT3 regulate p63 isoform expression in keratinocytes during regeneration

11 citations , November 2015 in “Experimental Dermatology”

The conclusion is that the IL-6/STAT3 activation affects p63 expression in healing wounds, which may help in hair follicle regeneration.

research KRT17: A Key Driver of Cancer Therapy Resistance and Emerging Therapeutic Target

November 2025 in “Cancer Management and Research”

Targeting Keratin 17 may help overcome cancer therapy resistance.

research 042 Characterization of Pathogenic CD8+ T Cells in an adoptive transfer Mouse Model of Alopecia Areata in C3H/HeJ mice

November 2025 in “Journal of Investigative Dermatology”

Certain CD8+ T cells attack hair follicles in alopecia areata, suggesting they could be targeted for treatment.

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