127 citations
,
December 2005 in “Experimental Dermatology” Stress can stop hair growth in mice, and treatments can reverse this effect.
112 citations
,
February 2001 in “Journal of Investigative Dermatology” Neuropeptides affect hair growth, with some speeding it up and others slowing it down.
27 citations
,
August 2003 in “Anais Brasileiros de Dermatologia” Neuropeptides affect skin inflammation, repair, and hair growth, with potential for therapy.
1 citations
,
January 2025 in “Burns & Trauma” Targeting Midkine can help reduce pain and itching in keloids.
April 2026 in “Journal of Dermatology Research” The skin communicates with the nervous system, and targeting neurohormones like melatonin and oxytocin could help treat skin issues.
Neuropeptides affect hair growth and could be used to control it.
2 citations
,
November 2017 in “Elsevier eBooks” Different substances that activate or block the androgen receptor can affect male development and treat conditions like prostate cancer.
11 citations
,
September 2019 in “Dermatologic Surgery” A substance called Vascular Endothelial Growth Factor can protect certain hair follicle stem cells from damage caused by androgens, suggesting a new possible treatment for hair loss.
8 citations
,
April 2011 in “Surgery today” A substance called sodium zinc dihydrolipoylhistidinate can significantly reduce hair loss caused by chemotherapy in rats.
220 citations
,
March 2020 in “Advanced functional materials” Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.
15 citations
,
May 2019 in “PLOS ONE” Substances from dental stem cells might help treat hair loss.
September 2023 in “Stem Cells International” Substances from fat-derived stem cells can promote hair growth and counteract hormone-related hair loss by activating a key hair growth pathway.
44 citations
,
April 2023 in “Genes & Diseases” Mesenchymal stem cells release substances that help tissue repair, and their effectiveness can be improved by understanding environmental influences.
54 citations
,
August 2019 in “Bioscience trends” Stem cells help repair tissue mainly by releasing beneficial substances, not by replacing damaged cells.
35 citations
,
May 2008 in “Drug and Alcohol Dependence” Female mice are less affected by certain substances that alter alcohol consumption compared to male mice.
8 citations
,
October 1989 in “International Journal of Dermatology” Cytochrome P-450 enzymes in the skin help break down various substances and could be targeted to treat skin conditions.
1 citations
,
January 2022 in “PubMed” Autologous serum, a substance from a patient's own blood, is effective in skin treatments for wound healing, skin rejuvenation, acne scars, and hair loss, with low risk of allergies or disease transmission.
18 citations
,
March 2020 in “Frontiers in Neuroendocrinology” The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.
January 2023 in “Journal of orthopedics & bone disorders” Platelet-rich plasma may not be very effective for bone healing and hair growth due to a substance it contains that blocks these processes.
September 2025 in “Journal of Drug Delivery and Therapeutics” Targeting hair follicles can effectively promote hair growth and treat hair disorders.
59 citations
,
May 2014 in “Expert Opinion on Therapeutic Targets” The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.
5 citations
,
May 2024 in “Journal of Cosmetic Dermatology” Engineered nanovesicles from hair follicle stem cells can effectively treat UVB-induced skin aging.
July 2025 in “Journal of Dermatology Research Reviews & Reports” Exosomes show promise as effective treatments for autoimmune skin diseases with fewer side effects.
Limbal Mesenchymal Stem Cell Secretome might help heal eye injuries by reducing inflammation and promoting tissue repair.
51 citations
,
June 1970 in “British journal of dermatology/British journal of dermatology, Supplement” Antiandrogens may help treat conditions like excessive hair growth, prostate tumors, male baldness, and acne by blocking male hormone effects.
January 2012 in “RepositóriUM (Universidade do Minho)” PLA nanoparticles can effectively deliver treatments to hair follicles, showing potential for hair therapy.
39 citations
,
March 2009 in “Archives of Dermatological Research” Apigenin may help promote hair growth and could treat hair loss.
15 citations
,
October 2021 in “Frontiers in Pharmacology” Natural volatiles and essential oils have health benefits and can enhance the effects of some medicines, but more research is needed to understand how they work and their possible side effects.
August 2025 in “MedScien” Tumor-targeted drug carriers can improve chemotherapy precision and reduce side effects.
August 2025 in “SciELO (SciELO Preprints)” Mesotherapy shows promise for treating alopecia but needs more research for long-term effectiveness.