research NCOG-40. RARE ADVERSE EFFECT OF TEMOZOLOMIDE IN A 65-YEAR-OLD FEMALE WITH GLIOBLASTOMA MULTIFORME: A CASE REPORT
Temozolomide can cause severe bone marrow suppression, leading to life-threatening complications.
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research An Uncontrolled Case Series Using a Botanically Derived, β-Cyclodextrin Inclusion Complex in Two Androgenetic Alopecia-Affected Male Subjects
Herbal formula shows promise for hair loss treatment.
research Accelerated, injectable, self-healing, scarless wound dressings using rGO reinforced dextran/chitosan hydrogels incorporated with PDA-loaded asiaticoside
The hydrogel dressings speed up healing and reduce scarring.
research Impact of Ester Promoieties on Transdermal Delivery of Ketorolac
Balancing lipophilicity and solubility is key for effective and safe ketorolac prodrugs.
research A randomized, double‐blind, controlled trial of testosterone gel treatment versus vehicle control on the facial hair of young men with beta‐thalassemia major
Testosterone gel helps increase facial hair in young men with beta-thalassemia major.
research Bioconversion, Pharmacokinetics, and Therapeutic Mechanisms of Ginsenoside Compound K and Its Analogues for Treating Metabolic Diseases
Ginsenoside compound K shows promise for treating metabolic diseases like obesity and diabetes, but more research is needed on its safety and effectiveness.
research 1350 Human scalp skin as an abundant and accessible source for eccrine sweat gland isolation and organ culture
Researchers found a new way to isolate sweat glands from the scalp for study and culture.
research Reprofiling synthetic glucocorticoid-induced leucine zipper fusion peptide as a novel and effective hair growth promoter
TAT-GILZ peptide promotes hair growth by boosting stem cell activity.
research Pharmacological Profile of 9,11-Dehydrocortexolone 17α-Butyrate (CB-03-04), a New Androgen Antagonist with Antigonadotropic Activity
CB-03-04 shows promise as a treatment for prostate issues due to its strong anti-androgen effects.
research Green tea leaves (Camellia sinensis (L.) Kuntze) extract and hibiscus leaves extract (Hibiscus tilliaceus L.) as topical hair growth promoter in microemulsion
research Topical Application of Thymidine Dinucleotide to Newborn Mice Reduces and Delays Development of UV-Induced Melanomas
Putting thymidine dinucleotide on newborn mice's skin can delay and reduce skin cancer.
research Anti-inflammatory, cyclooxygenase inhibitory and antioxidant activities of standardized extracts of Tridax procumbens L.
Extracts from Tridax procumbens L. have strong anti-inflammatory and antioxidant effects and block inflammation-causing enzymes.
research Green Technologies in the Generic Pharmaceutical Industry
Green technologies can make the pharmaceutical industry more sustainable by reducing waste.
research Cryopreservation of engineered hair follicle germs for hair regenerative medicine
DMSO and microfinger devices show promise for preserving hair grafts for hair loss treatments.
research P381 Kinetics of Titan cells generation and transcriptome modifications comparing three in vitro protocols
Three different methods were compared for creating Titan cells, a type of fungus cell. The OZ method made the most cells initially, but the number dropped quickly. The EB method also made a lot of cells, but the number also dropped. The AA method made fewer cells, but the number stayed steady. The methods also affected which genes were active in the cells.
research Advancements in Therapeutic Deep Eutectic Solvents as Multifunctional Transdermal Delivery Systems
TheDES improve drug delivery through the skin but need more safety checks.
research Double Network Physical Crosslinked Hydrogel for Healing Skin Wounds: New Formulation Based on Polysaccharides and Zn2+
The new hydrogel with zinc and polysaccharides improves wound healing and has antibacterial properties.
research Elicitor mediated enhancement of wedelolactone in cell suspension culture of Eclipta alba (L.) Hassk
Adding yeast extract and methyl jasmonate to Eclipta alba cell cultures increased the production of the compound wedelolactone.
research A TA/Cu2+ Nanoparticle Enhanced Carboxymethyl Chitosan-Based Hydrogel Dressing with Antioxidant Properties and Promoting Wound Healing
The hydrogel is safe, reduces oxidation, and helps heal wounds effectively.
research 41701 Efficacy of the Oral JAK1/JAK2 Inhibitor CTP-543 (Deuruxolitinib) in Adult Patients with Moderate to Severe Alopecia Areata: Results from the Multinational Double-Blind, Placebo-Controlled THRIVE-AA1 Phase 3 Trial
CTP-543 effectively promotes hair regrowth in adults with moderate to severe alopecia areata.
research Bilayer dressing based on aerogel/electrospun mats with self-catalytic hydrogen sulfide generation and enhanced antioxidant ability
The dressing generates hydrogen sulfide to help heal wounds faster by reducing inflammation and promoting cell growth.
research A Comprehensive Review on Deep Eutectic Solvents and Its Use to Extract Bioactive Compounds of Pharmaceutical Interest
Deep eutectic solvents can replace toxic solvents in extracting useful compounds for medicines.
research Citrullus colocynthis: A Treasure of Phytochemical, Pharmacological, Pesticidal and Nematicidal Compounds
Citrullus colocynthis is a valuable natural option for medicine and pest control.
research Promotion of anagen, increased hair density and reduction of hair fall in a clinical setting following identification of FGF5-inhibiting compounds via a novel 2-stage process
New compounds were found to help increase hair growth and decrease hair loss.
research Gelatin nanoparticles & nanocrystals for dermal delivery
Improved methods create smaller, more effective gelatin nanoparticles for skin delivery, and new caffeine nanocrystals enhance absorption and effectiveness.
research Antibacterial quaternary ammonium chitosan/carboxymethyl starch/alginate sponges with enhanced hemostatic property for the prevention of dry socket
The sponges effectively prevent dry socket by stopping bleeding and killing bacteria after tooth extraction.
research Investigation of the Mitigation of DMSO-Induced Cytotoxicity by Hyaluronic Acid following Cryopreservation of Human Nucleus Pulposus Cells
Hyaluronic acid reduces cell damage from DMSO in preserved human cells.
research STRESS AND AGING*
Anabolic steroids may help prevent aging effects by reducing toxicity, not by their usual functions.
research Preliminary investigations of rat skin after topical application of optical clearing agent
The skin fully recovered after using the optical clearing agent, showing no long-term harm.
research Synthesis and structure–activity investigation of iodinated arylhydantoins and arylthiohydantoins for development as androgen receptor radioligands
Scientists created iodinated arylhydantoins and arylthiohydantoins that could potentially be used for imaging prostate cancer. Some versions with specific side-chains showed high potential for this use.