research Can we teach old drugs new tricks?—Repurposing of neuropharmacological drugs for inflammatory skin diseases
Old neuropharmacological drugs might be effective for treating inflammatory skin diseases.
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420-450 / 1000+ results research Efficacy of metformin therapy in adolescent girls with androgen excess: relation to sex hormone–binding globulin and androgen receptor polymorphisms
Metformin works better for adolescent girls with PCOS who have certain genetic variations.
research Alopecia Areata in the Elderly: A 10-Year Retrospective Study
Alopecia areata in elderly people is usually mild and responds well to treatment.
research Game Changers: Blockbuster Small-Molecule Drugs Approved by the FDA in 2024
In 2024, the FDA approved 27 innovative small-molecule drugs, with many offering significant treatment improvements.
research Triglycerides, independent of Ferriman Gallwey Score, is a main determinant of free testosterone index in PCOS
High triglyceride levels are a key factor affecting testosterone levels in women with PCOS.
research Cardiometabolic Risk Factors in Atorvastatin-Treated Women with Euthyroid Autoimmune Thyroiditis
Atorvastatin is less effective for women with Hashimoto's thyroiditis.
research Clinical Presentations and Comorbidities of Pediatric Alopecia Areata
Pediatric alopecia areata needs more research to understand its characteristics and related conditions.
research Medical Dermatology
Early diagnosis, innovative treatments, and considering systemic conditions are crucial in dermatological care.
research Logic-based modeling and drug repurposing for the prediction of novel therapeutic targets and combination regimens against E2F1-driven melanoma progression
Tadalafil and Finasteride may help treat aggressive melanoma.
research Hair and Nail Manifestations of Systemic Disease
Early baldness in men may indicate risks for obesity, metabolic syndrome, insulin resistance, and heart disease, similar to women with PCOS. Alopecia areata is often linked with autoimmune diseases and mental health issues. Certain hair disorders are due to genetic issues, and chemotherapy can cause hair loss through specific biological pathways. Iron deficiency's link to hair loss is still disputed.
research Alopecia areata
Alopecia areata is an autoimmune disease with genetic links, treatable with certain medications, and can affect mental health.
research Hair metal dysregulation in Parkinson’s disease: Implications for diagnosis and gut-brain axis involvement
Hair metal analysis may help diagnose Parkinson's disease and suggests gut involvement.
research The Off-Label Use of Selective Serotonin Reuptake Inhibitors for Sexual Behavior Management: Risks and Considerations
SSRIs may help manage sexual behavior in dementia patients, but they can cause long-lasting sexual dysfunction.
research Onycholysis in an elderly woman: Proposal for treatment with Coix seed extract administration
Coix seed extract helped resolve onycholysis in an elderly woman.
research Assessing medication use patterns among patients with polycystic ovary syndrome at a tertiary care teaching hospital in South Korea: A retrospective study
Most patients with PCOS were prescribed medroxyprogesterone acetate or oral contraceptives, with some experiencing side effects or needing prescription changes.
research Patient Satisfaction and Quality of Life Among Adult Women with Androgenetic Alopecia Using 5% Topical Minoxidil.
Most women with hair loss using 5% topical Minoxidil are satisfied with the treatment, but hair loss still affects their daily habits and social life.
research Characterization of Hair Follicle Antigens Targeted by the Anti-Hair Follicle Immune Response
Alopecia areata is an autoimmune disorder causing hair loss, linked to specific hair follicle antigens and genetic factors.
research Recent Advances in the Pathogenesis of Autoimmune Hair Loss Disease Alopecia Areata
Alopecia areata is caused by immune system attacks on hair follicles, often triggered by viral infections.
research Effects of Melatonin Supplementation on Hormonal, Inflammatory, Genetic, and Oxidative Stress Parameters in Women With Polycystic Ovary Syndrome
Melatonin may improve some hormonal and inflammatory issues in women with PCOS.
research Organoid technology for tissue engineering
Organoid technology helps create mini-organs for studying diseases and testing drugs.
research Genetic Basis of Alopecia Areata
More research is needed to understand the genetic causes of Alopecia areata to develop better treatments.
research Chronic overlapping pain conditions and nociplastic pain
Nociplastic pain is a complex, heritable trait with genetic links to chronic and neuropathic pain.
research Long‐term safety and efficacy of ritlecitinib in adults and adolescents with alopecia areata and at least 25% scalp hair loss: Results from the ALLEGRO ‐LT phase 3, open‐label study
Ritlecitinib is effective and safe for treating alopecia areata, promoting significant hair regrowth.
research Expert Opinion: Migraine, Psychiatric Comorbidities, and Treatment
People with migraines often have mental health conditions, and treatment should be personalized to address both issues safely.
research Lithium: one drug, five complications
Lithium poisoning can cause severe health complications and requires careful monitoring.
research Effects of Low-Dose Spironolactone Combined with Metformin or Either Drug Alone on Insulin Resistance in Patients with Polycystic Ovary Syndrome: A Pilot Study
Combining spironolactone with metformin reduces insulin resistance in PCOS better than either drug alone.
research The Role of Probiotics and Synbiotics on Hirsutism
Probiotics and synbiotics might help manage hirsutism by improving insulin resistance.
research Acetyl-CoA synthesis in the skin is a key determinant of systemic lipid homeostasis
Skin acetyl-CoA synthesis is crucial for overall lipid balance.
research Successful treatment of severe atopic dermatitis and alopecia universalis with upadacitinib in a 29-year-old male patient
Upadacitinib effectively improved severe atopic dermatitis and alopecia universalis in a 29-year-old man.
research Safety and Efficacy of Ritlecitinib for the Treatment of Patients with Alopecia Areata: A Systematic Review and Meta-Analysis of Controlled Trials
Ritlecitinib effectively treats alopecia areata with manageable side effects.