121 citations
,
April 2008 in “The Journal of Clinical Endocrinology & Metabolism” Insulin sensitizers may slightly reduce hirsutism but are less effective than other treatments.
99 citations
,
July 2012 in “PLoS Genetics” A mutation in the KRT75 gene causes frizzle feathers in chickens.
85 citations
,
March 2002 in “Body & Society” The document concludes that cosmetic surgery is still mainly a practice for women and the gender gap in this field is expected to continue.
82 citations
,
August 2017 in “Cell Reports” An imbalanced gut and lack of biotin can cause hair loss in mice.
77 citations
,
April 2009 in “British Journal of Dermatology” Aromatase gene variation may increase female hair loss risk.
74 citations
,
January 2006 in “Endocrine journal” Low-dose gonadotropin treatment is effective for infertility in women with PCOS, leading to high ovulation rates and comparable pregnancy rates with fewer complications.
72 citations
,
April 2008 in “Organogenesis” Wnt signaling is crucial for skin and hair development and its disruption can cause skin tumors.
66 citations
,
September 2008 in “Dermatologic therapy” The conclusion is that the best initial treatment for hirsutism is usually oral contraceptives, with the addition of antiandrogens or insulin sensitizers if needed, and topical eflornithine or laser treatments as supplementary options.
60 citations
,
April 2012 in “Physiology” The document concludes that understanding hair and feather regeneration can help develop new regenerative medicine strategies.
60 citations
,
February 2010 in “Gynecological Endocrinology” Metformin combined with lifestyle changes improves insulin resistance and reduces testosterone levels in women with PCOS more than lifestyle changes alone.
57 citations
,
November 2006 in “International Journal of Cancer” A49T gene variant linked to higher prostate cancer risk, lower hormone levels, and slightly reduced balding risk.
47 citations
,
May 2012 in “Wiley Interdisciplinary Reviews-Developmental Biology” The conclusion is that understanding how feathers and hairs pattern can help in developing hair regeneration treatments.
47 citations
,
July 1967 in “Science” Not eating enough protein can cause hair roots to shrink and lose color, and hair to become thinner.
38 citations
,
October 2011 in “Analytical biochemistry” Hair proteins have weak spots in their α-helical segments.
37 citations
,
April 2010 in “FEBS Letters” The study concludes that the EDA2R gene is activated by p53 during chemotherapy but is not necessary for chemotherapy-induced hair loss.
34 citations
,
January 2011 in “Fundamental & Clinical Pharmacology” New treatments for PCOS show promise, but no current medication treats all aspects of the condition.
29 citations
,
January 2011 in “Journal of Obstetrics and Gynaecology” Insulin resistance in women with PCOS can lead to serious health issues, but lifestyle changes and certain medications can help manage symptoms.
28 citations
,
January 2016 in “Vitamins and hormones” Thymosin β4 helps improve skin healing and reduce scarring.
28 citations
,
March 2010 in “British Journal of Dermatology” Genetic marker rs12558842 strongly linked to male hair loss.
25 citations
,
September 2006 in “Birth Defects Research” Different processes create patterns in skin and things like hair and feathers.
24 citations
,
October 2024 in “Process Biochemistry” Optimal conditions for extracting beneficial compounds from Carthamus caeruleus L. rhizomes were identified, improving efficiency.
19 citations
,
July 2017 in “PLoS ONE” Cell characteristics change with passage numbers, affecting experiment results.
18 citations
,
March 2014 in “Current Pharmaceutical Biotechnology” Metformin helps regulate menstrual cycles, induce ovulation, and improve pregnancy outcomes in women with PCOS.
18 citations
,
January 2000 in “Food Science and Technology Research” Apple polyphenols, especially from unripe apples, can help prevent cells from turning into fat cells.
17 citations
,
October 2012 in “Dermatologic clinics” Treating excessive hair in women requires a holistic approach, including medical, aesthetic, and emotional support.
17 citations
,
December 2008 in “Dermatology” Taking metformin with intense-pulsed-light therapy improves hair removal for people with PCOS.
16 citations
,
January 2007 in “Journal of Obstetrics and Gynaecology” The document suggests various treatments for PCOS, including medication for menstrual issues, insulin resistance, and excess hair, as well as fertility treatments, while highlighting the need for personalized care and lifestyle changes.
13 citations
,
September 2024 in “Frontiers in Pharmacology” Morroniside has many health benefits, including protection against diabetes complications, bone and brain diseases, heart and skin issues, and it supports hair growth and reduces inflammation.
13 citations
,
May 2021 in “Plants” The leaf extract of Leea indica may reduce inflammation, dissolve blood clots, and promote hair growth.
13 citations
,
December 2018 in “Development, Growth & Differentiation” Sex hormones, especially estradiol, can change chicken feather shapes and colors.