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GlossaryTissue Growth

cells multiply and increase in size within a tissue

Tissue growth, also known as tissue development or tissue expansion, refers to the process by which cells within a tissue multiply and increase in size, leading to the enlargement and maturation of that tissue. This process is crucial for normal development, healing, and regeneration in the body. It involves a complex interplay of cellular activities, including cell division, differentiation, and extracellular matrix production.

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research Chemotropic Neomorphogenesis of Hemodynamically Active Hypervascular Patterns in Hare Skin by a Monocytic Polypeptide Mediator for Blood Vessel Growth (Monocyto-Angiotropin) Promotes Tissue Hyperfunction (Hair Growth)

1 citations , January 1985 in “Protides of the biological fluids”

Injecting monocyto-angiotropin into hare skin increases hair growth by forming new blood vessels.

research Reprogramming of Aged Dermal Papilla Cells in Vitro: In Silico Insight into the Biomarkers of Hair Growth and Tissue Repair

December 2025 in “Preprints.org”

Aging dermal papilla cells can be reprogrammed for potential hair growth and skin repair.

research Partial interchangeability of Fz3 and Fz6 in tissue polarity signaling for epithelial orientation and axon growth and guidance

28 citations , October 2014 in “Development”

Fz3 and Fz6 can partially replace each other in tissue polarity and axon guidance.

research 4-Aminopyridine Induces Nerve Growth Factor to Improve Skin Wound Healing and Tissue Regeneration

July 2022 in “Biomedicines”

4-Aminopyridine improves skin wound healing and tissue regeneration by increasing cell growth and promoting nerve repair.

research Hair growth and restoration by transcriptional control of tissue regeneration in cancer recovery process by Huaier.

July 2022 in “Research Square (Research Square)”

Huaier helps hair grow back and repairs tissue after cancer treatment.

research Hair Growth Promoting Effect of Dermal Papilla Like Tissues from Canine Adipose-Derived Mesenchymal Stem Cells in Athymic Nude Mice

January 2016

Tissue from dog stem cells helped grow hair in mice.

research Development of growth factor-incorporating liposomes for integration into scaffolds as a method to improve tissue regeneration

12 citations , September 2021 in “The International Journal of Developmental Biology”

Liposomal carriers can improve tissue regeneration by stabilizing and retaining growth factors.

research Hair growth promoting effects of adipose tissue-derived stem cells

81 citations , December 2009 in “Journal of Dermatological Science”

Fat tissue stem cells may help increase hair growth.

research Dermal Adipose Tissue Secretes HGF to Promote Human Hair Growth and Pigmentation

29 citations , January 2021 in “Journal of Investigative Dermatology”

Fat under the skin releases HGF which helps hair grow and gain color.

The Effects of Negative Pressure by External Tissue Expansion Device on Epithelial Cell Proliferation, Neo-Vascularization, and Hair Growth in a Porcine Model

research The Effects of Negative Pressure by External Tissue Expansion Device on Epithelial Cell Proliferation, Neo-Vascularization and Hair Growth in a Porcine Model

16 citations , April 2016 in “PLoS ONE”

Negative pressure treatment improved skin thickness, blood vessel growth, and hair growth.

research Expression of transforming growth factor-beta (TGF-beta 1) and insulin-like growth factor II (IGF-II) messenger RNA in the developing subcutaneous tissue (SQ) of the fetal pig.

11 citations , January 1992 in “PubMed”

TGF-beta 1 and IGF-II mRNA have specific patterns in pig subcutaneous tissue, affecting fat and muscle development.

research Role of Growth Factors-Rich Plasma, Gel and Membrane in Dermal Wound Healing and Injured Tissue Restoration and Regeneration

1 citations , November 2021 in “European journal of medical and health sciences”

Growth factors-rich plasma treatments can significantly speed up wound healing and tissue regeneration.

research Tissue microarray를 이용한 사이모신 베타4(Thymosin β4)와 vascular endothelial cell growth factor (VEGF)의 정상 인간 조직 발현 양상 연구

December 2009 in “생명과학회지”

Thymosin β4 and VEGF are important for organ function and may help with blood vessel formation.

research Editorial: Growth and Tissue Regeneration with focus on Proteoglycans

March 2023 in “Frontiers in Cell and Developmental Biology”

Proteoglycans are vital for tissue growth and healing, with potential as treatment targets.

Hair Growth Promoting Effect of Dermal Papilla-Like Tissues from Canine Adipose-Derived Mesenchymal Stem Cells Through Vascular Endothelial Growth Factor

research Hair growth promoting effect of dermal papilla like tissues from canine adipose-derived mesenchymal stem cells through vascular endothelial growth factor

8 citations , January 2016 in “Journal of Veterinary Medical Science”

Lab-made tissues from dog fat stem cells can help grow hair by releasing a growth factor.

research Hair Growth Promoting Potential of Phospholipids Purified from Porcine Lung Tissues

3 citations , March 2015 in “Biomolecules & Therapeutics”

Phospholipids from pig lungs can significantly promote hair growth.

research [Research progress in regulation of hair growth by dermal adipose tissue].

1 citations , May 2024 in “PubMed”

Dermal fat helps control hair growth, but more research is needed.

Transforming Growth Factor-Beta in Stem Cells and Tissue Homeostasis

research Transforming growth factor-β in stem cells and tissue homeostasis

245 citations , January 2018 in “Bone Research”

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

research Expression of nerve growth factor in skin tissues and its effect on the proliferation of outer root sheath cells in cashmere goats

1 citations , July 2016 in “Livestock science”

Nerve growth factor helps cashmere goat hair cells grow and is more active during the hair growth phase.

research Fibroblast growth factors: key players in regeneration and tissue repair

154 citations , November 2017 in “Development”

Fibroblast Growth Factors (FGFs) are important for tissue repair and regeneration, influencing cell behavior and other factors involved in healing, and are crucial in processes like wound healing, bone repair, and hair growth.

Single-Cell Transcriptomics Reveals Hair Growth Retardation Mediated by Aberrant Connective Tissue Sheath Contraction in Male Androgenetic Alopecia

research Single-cell transcriptomics reveals hair growth retardation mediated by aberrant connective tissue sheath contraction in male androgenetic alopecia

February 2026 in “Nature Communications”

Inhibiting connective tissue sheath contraction may improve hair growth in male pattern baldness.

research Cells, growth factors and biomaterials used in tissue engineering for hair follicles regeneration

November 2022 in “Regenerative Therapy”

Advancements in tissue engineering show promise for hair follicle regeneration to treat hair loss.

research Faculty Opinions recommendation of Dermal adipose tissue secretes HGF to promote human hair growth and pigmentation.

March 2021 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

Fat tissue around hair follicles releases a growth factor that helps hair grow and develop color.

research Leptin of dermal adipose tissue is differentially expressed during the hair cycle and contributes to adipocyte‐mediated growth inhibition of anagen‐phase vibrissa hair

30 citations , October 2014 in “Experimental Dermatology”

Leptin from skin fat can slow hair growth during certain phases.

research Effect of Growth Phase on Deposition of Selenium (Se) in Tissues of Rats Fed Elevated Dietary Levels of Se as Either L-Selenomethionine or Sodium Selenate

4 citations , January 1989

Hair and nails can indicate selenium levels in the body.

research Growth Factor and Growth Factor Receptor Localization in the Hair Follicle Bulge and Associated Tissue in Human Fetus

94 citations , March 1996 in “Journal of Investigative Dermatology”

research Radiofrequency treatment induces fibroblast growth factor 2 expression and subsequently promotes neocollagenesis and neoangiogenesis in the skin tissue

32 citations , May 2017 in “Lasers in medical science”

Radiofrequency treatment helps rejuvenate skin by boosting collagen and blood vessel growth.

research Chest hair micrografts display extended growth in scalp tissue: a case report

30 citations , August 2004 in “British Journal of Plastic Surgery”

Chest hair can be successfully used for scalp hair transplants, growing longer like scalp hair.

research Finasteride Reduces Microvessel Density and Expression of Vascular Endothelial Growth Factor in Renal Tissue of Diabetic Rats

7 citations , March 2015 in “The American Journal of the Medical Sciences”

Finasteride helps reduce blood vessel growth in diabetic rat kidneys.

research Synthesis of nerve growth factor mRNA in cultures of developing mouse whisker pad, a peripheral target tissue of sensory trigeminal neurons.

5 citations , March 1993 in “The Journal of Cell Biology”

A soluble factor in developing mouse whisker pads boosts nerve growth factor mRNA production.