September 2017 in “Journal of Investigative Dermatology” Certain miRNAs might be involved in a hair loss condition called frontal fibrosing alopecia and could possibly help in its diagnosis.
228 citations
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September 2012 in “Trends in Neurosciences” Nerves are crucial for the regeneration of various body parts in many animals.
220 citations
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March 2020 in “Advanced functional materials” Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.
194 citations
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March 2003 in “American Journal of Pathology” Stress stops hair growth in mice by causing early hair growth phase end and harmful inflammation through a specific nerve-related pathway.
188 citations
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March 2018 in “Frontiers in Immunology” Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.
93 citations
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November 2018 in “Carbohydrate Polymers” New nanocomposites with copper show promise for healing burn wounds and regenerating skin.
68 citations
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November 2012 in “Journal of Investigative Dermatology” Prostaglandin D2 blocks new hair growth after skin injury through the Gpr44 receptor.
44 citations
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January 2019 in “Journal of Translational Medicine” Macrophages are essential for successful skin growth in reconstructive surgery.
28 citations
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February 2014 in “PLoS ONE” Epidermal stem cells on a special membrane helped mice regrow full skin with hair and functions.
26 citations
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July 2012 in “Epilepsy & Behavior” Finasteride worsens seizures in epilepsy rats and speeds up epileptogenesis in mice.
10 citations
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June 2019 in “Journal of Tissue Engineering and Regenerative Medicine” Scientists successfully grew new hair follicles in regenerated mouse skin using mouse and human cells.
10 citations
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October 1992 in “Hormone and Metabolic Research” Finasteride safely lowers DHT levels without affecting hormone levels, helping with conditions like enlarged prostate, acne, and hair loss.
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October 2019 in “Jo'jig gonghag gwa jaesaeng uihag/Tissue engineering and regenerative medicine” Rice bran extract boosts melanin production in hair follicles.
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May 2020 in “Journal of visualized experiments” Controlled light treatment in mouse skin speeds up healing and hair growth.
1 citations
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January 2024 in “Theranostics” Exosomes show promise for future tissue regeneration.
132 citations
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January 2017 in “International Journal of Molecular Sciences” Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.
30 citations
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February 2022 in “Stem Cell Reviews and Reports” Stem cell treatments may improve burn wound healing.
506 citations
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January 2012 in “Molecular and Cellular Endocrinology” Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.
480 citations
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August 2014 in “Nature Biotechnology” Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.
223 citations
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December 2010 in “The Journal of Sexual Medicine” Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.
144 citations
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September 2012 in “Genes & development” Aging causes skin stem cells to work less effectively.
124 citations
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March 2012 in “JAMA” Testosterone's muscle-building effects do not require its conversion to DHT.
124 citations
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January 1993 in “The Prostate” Finasteride effectively inhibits 5α reductase, while plant extracts like Permixon and Bazoton don't show significant results.
114 citations
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December 1951 in “Archives of Dermatology” Aminopterin strongly suppresses epithelial tissues and can treat certain skin conditions but has significant side effects.
75 citations
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November 1996 in “Fertility and Sterility” Finasteride effectively reduces hair growth in women with idiopathic hirsutism, but requires careful contraception during treatment.
70 citations
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August 1995 in “Fertility and Sterility” Finasteride reduces hairiness and androgen levels in women with unexplained excessive hair growth.
70 citations
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June 1993 in “Biochemistry” Finasteride slowly binds to 5-alpha-reductase, affecting enzyme stability and inhibitor potency.
66 citations
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April 2017 in “International Journal of Andrology” Men taking 5α-reductase inhibitors for enlarged prostate have a higher chance of experiencing reduced sexual desire and erectile dysfunction.
65 citations
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June 2003 in “EMBO journal” Noggin overexpression delays eyelid opening by affecting cell death and skin cell development.
59 citations
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September 1994 in “The Journal of Clinical Endocrinology and Metabolism” Finasteride reduces scalp DHT levels, potentially treating male pattern baldness.