359 citations
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January 2015 in “Cold Spring Harbor Perspectives in Medicine” Hair growth phase and certain genes can speed up wound healing, while an inflammatory mediator can slow down new hair growth after a wound. Understanding these factors can improve tissue regeneration during wound healing.
7 citations
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July 2012 in “Regenerative Medicine” New treatments for diabetes, central nervous system repair, and cartilage injury were found, and a way to create functional hair follicles from stem cells was developed.
14 citations
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May 2021 in “Marine Drugs” PDRN, derived from salmon sperm, shows promise in healing wounds, reducing inflammation, and regenerating tissues, but more research is needed to understand its mechanisms and improve its use.
291 citations
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April 2010 in “Gastroenterology” Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.
160 citations
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June 2008 in “American Journal Of Pathology” EGFR signaling is crucial for skin and hair health, and targeting it could help treat skin diseases and cancer.
52 citations
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January 2023 in “Annual Review of Immunology” Immune-epithelial interactions are crucial for tissue repair, but unchecked can cause diseases.
39 citations
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August 2017 in “Annual Review of Genetics” Understanding tissue regeneration in animals can improve regenerative medicine.
July 2017 in “Cancer Research” Krt15+ cells in mice can resist radiation, regenerate tissue, and start tumors, suggesting new cancer treatment targets.
January 2014 in “Durham e-Theses (Durham University)” Notch1 helps skin heal by attracting cells that aid repair.
85 citations
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October 2015 in “Proceedings of the National Academy of Sciences of the United States of America” NF-κB is crucial for zebrafish heart repair, affecting heart cell growth and repair processes.
6 citations
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December 2024 in “F1000Research” Fibroblast and immune cell interactions affect tissue repair and fibrosis.
32 citations
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December 2017 in “Stem Cells Translational Medicine” We need to understand more about regeneration to improve human tissue healing.
11 citations
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January 2022 in “Theranostics” Wnt4 is essential for heart repair and could be a target for heart disease treatment.
3 citations
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May 2024 in “Frontiers in Physiology” Sex hormone supplements help improve breathing and nerve recovery after spinal injury in rats.
28 citations
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March 2017 in “Endocrinology” Removing vitamin D and calcium receptors in mice skin cells slows down skin wound healing.
7 citations
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March 2023 in “The Journal of Biochemistry” LONRF1 is important for oxidative damage response and tissue remodeling during wound healing.
January 2026 in “Open Life Sciences” Exosomes from stem cells help repair irradiated salivary glands by boosting cell growth.
86 citations
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April 2016 in “Nature Communications” Notch1 helps skin heal by attracting specific immune cells.
3 citations
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February 2023 in “International Journal of Molecular Sciences” Autologous Platelet and Extracellular Vesicle-Rich Plasma (PVRP) has potential in enhancing tissue regeneration and improving hair conditions, but its effectiveness varies due to individual differences.
1201 citations
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January 2010 in “Science” Active and quiescent stem cells work together in mammals to maintain and repair tissues.
A new microneedle patch helps repair spinal cord injuries by reducing scarring and promoting nerve growth.
18 citations
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March 2024 in “Frontiers in Pharmacology” Natural plant products like Proanthocyanidins and curcumin may help treat ischemic stroke by reducing inflammation.
55 citations
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April 2010 in “Cancer and Metastasis Reviews” TGFβ's manipulation of inflammation and immune cells affects cancer spread, suggesting new treatment strategies and biomarkers.
2 citations
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January 2015 in “BioMed Research International” Growth factor treatments are increasingly used in medicine but require more research to fully understand their mechanisms.
May 2020 in “Research Square (Research Square)” Bone marrow stem cells help heal intestines and reduce death in liver failure.
37 citations
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July 2016 in “Current Opinion in Cell Biology” Live imaging has advanced our understanding of stem cell behavior and raised new research questions.
68 citations
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December 2014 in “Cell Biochemistry and Function” Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.
41 citations
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December 2018 in “Experimental Dermatology” Understanding how melanocyte stem cells work could lead to new treatments for hair graying and skin pigmentation disorders.
31 citations
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March 2015 in “The Journal of Steroid Biochemistry and Molecular Biology” Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.
3 citations
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August 2024 Deep skin fibroblasts help recruit immune cells for better wound healing.