research Tracking adult stem cells
A combined approach is needed to fully understand adult stem cells, with genetic lineage-tracing being crucial.
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research Gene network analysis reveals candidate genes related with the hair follicle development in sheep
Key genes crucial for sheep hair follicle development were identified, aiding fine wool breeding and human hair loss research.
research Advances in precise cell manipulation
Precise cell manipulation technologies are advancing but still face challenges in improving accuracy for medical use.
research ST14 interacts with TMEFF1 and is a predictor of poor prognosis in ovarian cancer
High levels of ST14 and TMEFF1 proteins in ovarian cancer are linked to worse patient outcomes and may be a new treatment target.
research Long-term live imaging, cell identification and cell tracking in regenerating crustacean legs
A new method allows detailed tracking of cell regeneration in crustacean legs.
research Perivascular Hair Follicle Stem Cells Associate with a Venule Annulus
Hair follicle stem cells rely on nearby blood vessels for their maintenance and function.
research Progenitor Cell Dysfunctions Underlie Some Diabetic Complications
Diabetes causes lasting cell dysfunctions, leading to serious complications even after blood sugar is controlled.
research Volume imaging to interrogate cancer cell-tumor microenvironment interactions in space and time
Advanced imaging methods have improved understanding of cancer cell interactions and treatment strategies.
research Research Techniques Made Simple: Optical Clearing and Three-Dimensional Volumetric Imaging of Skin Biopsies
3D imaging of skin biopsies offers better accuracy but is time-consuming and can't clear melanin.
research Selective androgen receptor modulators: a critical appraisal
SARMs show promise but need more evidence to prove they're better than traditional androgens.
research Lung Cancer Awareness Symposium Highlights Necessary Focus Areas for Research
More research is needed on better diagnostics, survivorship, and the impact of genetic mutations in lung cancer.
research Who Am I? Eyebrow Follicles Minimize Donor-Derived DNA for Germline Testing After Hematopoietic Stem Cell Transplantation
Eyebrow follicles are best for accurate genetic testing after stem cell transplants.
research Current Biomedical Applications of 3D-Printed Hydrogels
3D-printed hydrogels show promise in medicine but face challenges in resolution, cell viability, cost, and regulations.
research The Intermediate Filament Architecture as Determined by X-Ray Diffraction Modeling of Hard α-Keratin
Hard α-keratin in hair has a unique, nonordered structure, different from other fibers.
research Building Fucoidan/Agarose-Based Hydrogels as a Platform for the Development of Therapeutic Approaches against Diabetes
Agarose/fucoidan hydrogels may help treat diabetes by supporting pancreatic cell growth.
research Transplanted hair follicle mesenchymal stem cells alleviated small intestinal ischemia–reperfusion injury via intrinsic and paracrine mechanisms in a rat model
Transplanted hair follicle stem cells can heal damaged rat intestines.
research Wnt/β-Catenin Signaling Stabilizes Hemidesmosomes in Keratinocytes
Wnt/β-catenin signaling is important for keeping skin cell attachment structures stable.
research Adaptive 3D Self‐Assembly of Colorectal Cancer Cells With Unchanged Tumor Phenotype and Drug Sensitivity
Colorectal cancer cells can adapt without losing their traits or drug sensitivity.
research Reawakening GDNF's regenerative past in mice and humans
Activating the GDNF-GFRα1-RET signaling pathway could potentially promote skin and limb regeneration in humans and could be used to treat hair loss and promote wound healing.
research The Dual Nature of Cellular Senescence: From Aging Signature to Regenerative Catalyst
Cellular senescence can both hinder and promote hair growth, suggesting new ways to treat hair loss.
research Multiomics-empowered Deep Phenotyping of Ulcerative Colitis Identifies Biomarker Signatures Reporting Functional Remission States
Microvascular damage and platelet issues persist in ulcerative colitis remission, helping assess disease states.
research A Novel Airway-Organoid Model Based on a Nano-Self-Assembling Peptide: Construction and Application in Adenovirus Infection Studies
A new lab-grown lung model helps study adenoviruses and test antiviral drugs.
research The cutting‐edge progress in bioprinting for biomedicine: principles, applications, and future perspectives
Bioprinting shows promise in medicine but needs collaboration to overcome challenges.
research Wnt/β-catenin signalling: function, biological mechanisms, and therapeutic opportunities
The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.
research Expression of keratin K14 in the epidermis and hair follicle: insights into complex programs of differentiation.
Keratin K14 expression varies between hair follicles and epidermis, affecting cell differentiation.
research LGR5 is a Marker of Poor Prognosis in Glioblastoma and is Required for Survival of Brain Cancer Stem‐Like Cells
High LGR5 levels in glioblastoma indicate poor prognosis and are essential for cancer stem cell survival.
research Matrix remodelling and MMP expression/activation are associated with hidradenitis suppurativa skin inflammation
Matrix changes and increased MMPs contribute to skin inflammation in hidradenitis suppurativa.
research Defining a Region of the Human Keratin 6a Gene That Confers Inducible Expression in Stratified Epithelia of Transgenic Mice
The human keratin 6a gene's specific sequences trigger expression in skin layers after injury.
research Is There a Histone Code for Cellular Quiescence?
There might be a specific histone code for cellular quiescence, but more research is needed.
research FOXP3 + regulatory T cells and age‐related diseases
Targeting regulatory T cells may help treat age-related diseases.