162 citations
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July 2011 in “Biomacromolecules” Chitosan nanofiber scaffolds improve skin healing and are promising for wound treatment.
150 citations
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June 2014 in “Biomaterials” Peptide hydrogels heal burn wounds faster and better than standard dressings.
146 citations
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July 2018 in “Regenerative Medicine” Understanding different types of skin cells, especially fibroblasts, can lead to better treatments for wound healing and less scarring.
135 citations
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December 2015 in “Expert Opinion on Biological Therapy” Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.
127 citations
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January 2015 in “Journal of Biological Rhythms” The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.
113 citations
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July 2020 in “International Journal of Molecular Sciences” Allogenic ASCs and ECM transplants are safe and effective for tissue regeneration.
113 citations
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December 2000 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” KGF and activin are crucial for skin healing and repair.
112 citations
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January 2014 in “Molecular and cellular therapies” Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.
85 citations
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July 2002 in “Pigment Cell Research” The article concludes that while we understand a lot about how melanocytes age and how this can prevent cancer, there are still unanswered questions about certain pathways and genes involved.
70 citations
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April 2020 in “Journal of Molecular Cell Biology” Organoid technology helps create mini-organs for studying diseases and testing drugs.
70 citations
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January 2014 in “International review of cell and molecular biology” Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.
65 citations
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June 2003 in “EMBO journal” Noggin overexpression delays eyelid opening by affecting cell death and skin cell development.
57 citations
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March 2018 in “International Journal of Molecular Sciences” The extracellular matrix is crucial for controlling skin stem cell behavior and health.
48 citations
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March 2019 in “Frontiers in Physiology” Wounds on the face usually heal with scars, but understanding how some wounds heal without scars could lead to better treatments.
47 citations
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March 2017 in “Materials Science and Engineering: C” Human amniotic membrane helps heal skin wounds faster and with less scarring.
47 citations
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July 2013 in “Pharmacological Reviews” Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.
44 citations
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September 2019 in “The EMBO Journal” Lymphatic vessels are essential for hair follicle growth and skin regeneration.
43 citations
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January 2011 in “Plastic and Reconstructive Surgery” Stem cells have great potential for improving wound healing, but more research is needed to find the best types and ways to use them.
39 citations
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April 2019 in “Journal of Biomaterials Science, Polymer Edition” RADA16 is a promising material for tissue repair and regenerative medicine but needs improvement in strength and cost.
38 citations
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February 2016 in “Surgery Journal” Facial plastic surgery has evolved to focus on less invasive techniques and innovative technologies for cosmetic and reconstructive procedures.
34 citations
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May 2021 in “Journal of Nanobiotechnology” The 3D electrospun fibrous sponge is promising for tissue repair and healing diabetic wounds.
30 citations
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May 2019 in “Medicinal Research Reviews” Combining stem cells and targeted treatments can improve muscle and skin healing after cleft repair.
28 citations
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September 2015 in “Wiener Klinische Wochenschrift” New skin substitutes for treating severe burns and chronic wounds are being developed, but a permanent solution for deep wounds is not yet available commercially.
22 citations
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June 2024 in “Cell” Understanding tissue self-organization can improve treatments for diseases and advance regenerative medicine.
22 citations
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November 2012 in “Journal of cosmetic dermatology” Stem cells can rejuvenate skin, restore hair, and aid in wound healing.
20 citations
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June 2019 in “Experimental Dermatology” The research suggests that autophagy-related genes might play a role in causing alopecia areata.
19 citations
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April 2015 in “Developmental Dynamics” The conclusion is that skin and hair patterns are formed by a mix of cell activities, molecular signals, and environmental factors.
16 citations
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December 2018 in “ACS Biomaterials Science & Engineering” The new patch made of cell matrix and a polymer improves wound healing and supports blood vessel growth.
16 citations
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December 2006 in “Expert Review of Dermatology” Hair follicles are essential for skin health, aiding in hair growth, wound healing, and immune function.
15 citations
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January 2020 in “ACS Applied Materials & Interfaces” Nanofiber structure helps regenerate hair follicles.