13 citations
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June 2017 in “Biochimie open” All five human steroid 5α-reductase enzymes are found in the endoplasmic reticulum.
August 2025 in “DS Reviews of Research in Life Sciences” Women with PCOS have higher levels of DHEA, IL-6, and TNF-α.
March 2023 in “The Journal of Urology” Higher SRD5A2 expression predicts better response to finasteride in treating urinary symptoms.
2 citations
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September 2022 in “Annals of Oncology” Mirvetuximab soravtansine improves quality of life and reduces symptoms more than standard chemotherapy in ovarian cancer patients.
May 2021 in “FEBS open bio”
16 citations
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July 2017 in “Rheumatology and Therapy” Tofacitinib, a medication for arthritis, showed potential for treating severe hair loss in a small Brazilian case series, but more research is needed.
COVID-19 infection is highly related to increased hair loss, especially in women.
15 citations
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December 2015 in “PLoS ONE” Fibroblasts can be mistaken for neural cells, so functional validation is needed.
June 2022 in “Frontiers in Immunology” Tofacitinib regrew hair in a man with total hair loss but raised cytokine levels, needing more research on possible side effects.
1 citations
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January 2017 in “Japanese Journal of Oral & Maxillofacial Surgery” The woman was cured of neurosyphilis after treatment with penicillin.
5 citations
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January 2021 in “Inflammatory Bowel Diseases” Tofacitinib improved ulcerative colitis, skin ulcers, and hair loss in a patient who didn't respond well to other treatments.
April 2015 in “Plastic and Reconstructive Surgery” TLR3 activation helps improve skin and hair follicle healing in mice.
7 citations
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June 2021 in “JAAD Case Reports” A woman had hair loss, nail changes, and skin peeling after a COVID-19 infection, which got better on their own.
May 2025 in “Drug Delivery and Translational Research” 17 citations
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September 2020 in “Inflammation and Regeneration” WNT activation in scalp fibroblasts boosts hair growth by increasing FGF9.
34 citations
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March 2007 in “Biochemical and Biophysical Research Communications” Thioredoxin reductase 1 does not affect glucocorticoid receptor activity in hair follicle cells.
Translation can lead to misunderstandings in clinical research.
2 citations
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September 2020 in “International Journal of Molecular Sciences” Removing certain hair follicle stem cells worsens skin reactions to allergens.
July 2018 in “Elsevier eBooks” Telogen Effluvium is a common, usually reversible hair loss condition, often improved by removing the trigger and possibly treated with various products, though their effectiveness is uncertain.
November 2020 in “Zenodo (CERN European Organization for Nuclear Research)”
September 2024 in “JAAD International” Telogen effluvium increased globally after COVID-19, especially in Asian and Latin regions.
7 citations
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December 2021 in “Journal of Infection” One in four people still had symptoms like weight loss, hair loss, and fatigue 12-14 weeks after recovering from COVID-19.
March 2025 in “European Journal of Medical Genetics” Tofacitinib helped improve symptoms and hair growth in a patient with Aicardi-Goutières syndrome.
88 citations
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August 2019 in “Nature communications” Researchers found a specific immune receptor in patients that causes severe skin reactions to a drug.
October 2022 in “Amplla Editora eBooks” The document's conclusion cannot be provided because the content is not available for analysis.
March 2005 in “European Urology Supplements”
March 2022 in “International Journal of Trichology” Tofacitinib may be effective for treating hair loss caused by alopecia areata that doesn't respond to other treatments.
10 citations
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November 2021 in “PLoS ONE” The T allele of the PTPN22 gene may increase the risk of alopecia areata.
December 2020 in “Ambiance in Life” COVID-19 increased the number of deaths in 2020 compared to 2018 and 2019.
August 2019 in “Stem cells” New treatments for hair loss, fertility, and wound healing are being explored.